Symptoma

Childhood Absence Epilepsy

CAE

Review of published reports confirmed this presentation to be atypical of this developmental lesion. The authors describe their patient and discuss this unexpected association and the relevant reports briefly. [ncbi.nlm.nih.gov]

  • Distractibility

    Item analysis within the subscales revealed that children with CAE demonstrate higher rates of hyperactive (overactivity and fidgetiness) and inattentive (forgetfulness and distractibility) problems, and require more supervision. [ncbi.nlm.nih.gov]

  • Neglect

    Abstract Automatic detections of paroxysms in patients with childhood absence epilepsy have been neglected for several years. [ncbi.nlm.nih.gov]

  • Focal Spikes

    PURPOSE: To better understand the nature of the focal spike-wave discharges (FSWDs) and focally led generalized spike-wave discharges (GSWDs) in typical childhood absence epilepsy (CAE) and by implication their nosologic and taxonomic significance. [ncbi.nlm.nih.gov]

  • 3-4 Hz Spikes

    Childhood absence epilepsy with tonic–clonic seizures and electroencephalogram 3–4‐Hz spike and multispike–slow wave complexes: linkage to chromosome 8q24. Am J Hum Genet 1998 ; 63 : 1117 –29. [doi.org]

  • Focal Epileptiform Discharges

    Among 214 patients with benign focal epileptiform discharges, 5 patients were identified with recorded EEG seizures (2.3%). [ncbi.nlm.nih.gov]

  • Epileptiform Activity

    The EEG at 41 years showed a slow background with bitemporal independent epileptiform activity. The GABRG2 (R43Q) mutation was present. [doi.org]

Seizure frequency was not associated with baseline measures of attention, executive function, or treatment outcome. [ncbi.nlm.nih.gov]

The long term prognosis of these patients seems to be good with an excellent response to anticonvulsant therapy. Copyright 2017 European Paediatric Neurology Society. Published by Elsevier Ltd. All rights reserved. [ncbi.nlm.nih.gov]

According the ILAE classification of epileptic seizures and epilepsy the etiology could be symptomatic or cryptogenic. [ncbi.nlm.nih.gov]

Epidemiologic data concerning early-onset CAE is scarce. We tried to specifically analyze the early-onset CAE and compare it with typical CAE. [ncbi.nlm.nih.gov]

Epidemiology of different types of epilepsy in school age children of Modena, Italy. Epilepsia 1980 ; 21 : 57 –62. Commission on Classification and Terminology of the International League Against Epilepsy. [doi.org]

However, recent interesting observations in animal models suggest that BCECTS and CAE could be pathophysiologically related and that genetic links could play a large role. [ncbi.nlm.nih.gov]

We found that the mutation in GABRG2 (encoding the gamma2-subunit) abolished in vitro sensitivity to diazepam, raising the possibility that endozepines do in fact exist and have a physiological role in preventing seizures. [ncbi.nlm.nih.gov]