Review of published reports confirmed this presentation to be atypical of this developmental lesion. The authors describe their patient and discuss this unexpected association and the relevant reports briefly. [ncbi.nlm.nih.gov]

• Epilepsy

  The aim of this study was the examination of memory abilities in other childhood common epilepsy syndromes (frontal lobe epilepsy (FLE), childhood absence epilepsy (CAE), and benign epilepsy with centrotemporal spikes (BECTS)) and the influence of epilepsy-related [ncbi.nlm.nih.gov]

• Nausea

  The most common adverse effects of treatment with valproate were fatigue, nausea, vomiting, increased appetite with weight gain, behavioural/psychiatric changes (decreased concentration, personality change, hyperactivity, attention problems, hostility [cochranelibrary.com]

• Vomiting

  The most common adverse effects of treatment with valproate were fatigue, nausea, vomiting, increased appetite with weight gain, behavioural/psychiatric changes (decreased concentration, personality change, hyperactivity, attention problems, hostility [cochranelibrary.com]

• Fear

  Howland, The T‐type calcium channel blocker Z944 reduces conditioned fear in Genetic Absence Epilepsy Rats from Strasbourg and the non‐epileptic control strain, European Journal of Neuroscience,, (2019). Gemma L. [doi.org]

  The latter is due to fears of a higher rate of fetal abnormalities in pregnancies exposed to valproate (Moore 2000). Preliminary studies suggested that lamotrigine may become the first‐line drug in AS (Buoni 1999). [cochranelibrary.com]

• Seizure

  The return of seizures after zonisamide discontinuation suggests that the seizure freedom may have been the result of the different mechanisms of action of the antiepileptic drugs. [ncbi.nlm.nih.gov]

• Generalized Tonic-Clonic Seizure

  Abstract About 40% of children with childhood absence epilepsy develop generalized tonic-clonic seizures. [ncbi.nlm.nih.gov]

• Generalized Seizure

  These observations also bolster the new ILAE definition of generalized seizures, suggesting that some so-called generalized seizures are not truly generalized but that they instead rapidly engage bilaterally distributed networks with clear asymmetries [ncbi.nlm.nih.gov]

  Clinical Information Epilepsy characterized by absence seizures Generalized seizure that manifests in a form of a brief episode of impairment of consciousness with or without accompanying motor phenomena such as clonic-tonic components, automatisms, or [icd9data.com]

• Convulsions

  There is a recognized genetic relationship between FS and CAE, yet the two syndromes have different ages of onset, and the physiology of absences and convulsions is distinct. [ncbi.nlm.nih.gov]

  Complex segregation analysis of febrile convulsions. Am J Hum Genet 1987 ; 41 : 249 –57. Sander T, Kretz R, Schulz H, Sailer U, Bauer G, Scaramelli A, et al. [doi.org]

  Suffczynski P, Kalitzin S, Lopes Da Silva FH. (2004) Dynamics of non-convulsive epileptic phenomena modeled by a bistable neuronal network. Neuroscience 126, 467-484. [scholarpedia.org]

• Apathy

  […] numbers 2 4 Increased appetite 15 Poor appetite 1 8 Diarrhoea 1 7 Dizziness 1 2 Hyperactivity 23 Attention problems 24 Hostility 22 Concentration decreased 18 Personality change 17 Sleep problem 17 Depression 11 Slow process speed 11 Memory problem 10 Apathy [cochranelibrary.com]

• 3-4 Hz Spikes

  4 years FS, A Bi C‐T spikes CAE Positive IV‐26 5 N 12 months 3 years FS N FS Positive IV‐27 3 N 18 months no FS, A 3 Hz GSW CAE Positive IV‐28 3 N 21 months 3 years FS, A 3 Hz GSW CAE Positive IV‐29 1 N 8 months no FS, afebrile tonic sz N FS + Positive [doi.org]

• Focal Spikes

  PURPOSE: To better understand the nature of the focal spike-wave discharges (FSWDs) and focally led generalized spike-wave discharges (GSWDs) in typical childhood absence epilepsy (CAE) and by implication their nosologic and taxonomic significance. [ncbi.nlm.nih.gov]

Patients with a shortest seizure of longer duration were more likely to demonstrate treatment success by both freedom-from-failure (p = 0.02) and SF (p = 0.005) criteria, even after controlling for age, treatment group, and number of seizures, with good [ncbi.nlm.nih.gov]

The long term prognosis of these patients seems to be good with an excellent response to anticonvulsant therapy. Copyright © 2017 European Paediatric Neurology Society. Published by Elsevier Ltd. All rights reserved. [ncbi.nlm.nih.gov]

According the ILAE classification of epileptic seizures and epilepsy the etiology could be symptomatic or cryptogenic. [ncbi.nlm.nih.gov]

Epidemiologic data concerning early-onset CAE is scarce. We tried to specifically analyze the early-onset CAE and compare it with typical CAE. [ncbi.nlm.nih.gov]

Epidemiology of different types of epilepsy in school age children of Modena, Italy. Epilepsia 1980 ; 21 : 57 –62. Commission on Classification and Terminology of the International League Against Epilepsy. [doi.org]

However, recent interesting observations in animal models suggest that BCECTS and CAE could be pathophysiologically related and that genetic links could play a large role. [ncbi.nlm.nih.gov]

We found that the mutation in GABRG2 (encoding the gamma2-subunit) abolished in vitro sensitivity to diazepam, raising the possibility that endozepines do in fact exist and have a physiological role in preventing seizures. [ncbi.nlm.nih.gov]