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Chlamydia Trachomatis Infection


Presentation

  • The aim of present study was to characterize the antibody response between two groups of individuals, having either a single C. trachomatis infection and or repeated infections.[ncbi.nlm.nih.gov]
Fever
  • Her cervical culture was negative for Chlamydia; however, cultures were not taken until two months after delivery and she had received antibiotics for postpartum fever and abdominal pain.[ncbi.nlm.nih.gov]
  • (in pelvic inflammatory disesease) asymptomatic in 80% of patients in males dysuria yellow mucopurulent discharge from the urethra unilateral pain and swelling of the scrotum fever asymptomatic in 50% of patients in newborns symptoms of conjunctivitis[medbullets.com]
  • Her cervical culture was negative for Chlamydia ; however, cultures were not taken until two months after delivery and she had received antibiotics for postpartum fever and abdominal pain.[pediatrics.aappublications.org]
  • […] he or she may be affected by other sexually transmitted infections that may be left untreated by the delivered medicine; (4) inform the partner that if symptoms of a more serious infection are present (such as abdominal, pelvic, or testicular pain, fever[health.ny.gov]
Anemia
  • Laboratory investigation revealed anemia and thrombocytopenia (hemoglobin 6 mmol/l; platelets 7 x 10(10)/l), remarkable polyclonal hypergammopathy (gamma immunoglobulin 7.7 g/dl) and subclinical disseminated intravascular coagulopathy (DIC).[ncbi.nlm.nih.gov]
Fever of Unknown Origin
  • We propose that Chlamydia trachomatis infection caused his illness and that urine PCR or LCR tests for Chlamydia is a convenient and useful investigation in sexually active males with generalised lymphadenopathy and fever of unknown origin.[ncbi.nlm.nih.gov]
Respiratory Distress
  • He showed mild respiratory distress and was treated with oral erythromycin for three weeks. He was discharged home at the age of 46 days.[ncbi.nlm.nih.gov]
  • At 31 days of age he had conjunctivitis and respiratory distress. Nasopharyngeal aspirate grew C trachomatis and serum IgM antibody titer was 1:32 for serotype J. The patient's mother had serum IgG antibody against C trachomatis serotype J.[pediatrics.aappublications.org]
Sputum
  • Respiratory sputum specimens were tested using RT-PCR targeting C. trachomatis cryptic plasmid.[ncbi.nlm.nih.gov]
Pleural Effusion
  • Ultrasound echographic study and magnetic resonance imaging showed pleural effusion and pelvic ascites.[ncbi.nlm.nih.gov]
Rectal Pain
  • Symptoms vary by site of infection and may include urethral irritation or discharge, dysuria, rectal pain or discharge, and tenesmus. Chlamydia epididymitis presents with unilateral supratesticular pain and swelling.[infectiousdiseaseadvisor.com]
  • pain, discharge, and/or bleeding.[medlineplus.gov]
  • ., rectal pain, discharge, and/or bleeding). 26-28 Sexually acquired chlamydial conjunctivitis can occur in both men and women through contact with infected genital secretions. 29 While chlamydia can also be found in the throats of women and men having[cdc.gov]
  • pain, mucoid or hemorrhagic discharge, fever, and/or tenesmus. [ 34 ] Diagnosis can be supported via anoscopy findings (mucopurulent discharge, pain, and spontaneous or induced bleeding).[std.uw.edu]
Chest Pain
  • We report the case of a 32-year-old male with Chlamydia trachomatis infection and admitted with chest pain, signs of myocardial damage and coronary arteries free from significant atherosclerotic disease.[ncbi.nlm.nih.gov]
Salpingitis
  • Chlamydia trachomatis has been implicated in salpingitis, cervicitis, urethritis, and peritonitis, This case shows that endometritis may also result from C. trachomatis infection and in such instances may be a contributing factor in infertility.[ncbi.nlm.nih.gov]
  • Salpingitis caused by Chlamydia runs a milder clinical course than salpingitis caused by gonococci or other etiology but salpingitis due to Chlamydia is regarded as one of the most important causes of tubal infertility and extrauterine pregnancy.[forskning.ku.dk]
  • Chlamydia trachomatis has been implicated in salpingitis, cervicitis, urethritis, and peritonitis. This case shows that endometritis may also result from C. trachomatis infection and in such instances may be a contributing factor in infertility.[annals.org]
  • In women, complications include pelvic inflammatory disease, salpingitis, and infertility. Approximately 25% to 30% of women who develop acute salpingitis become infertile.(2) Complications among men are rare, but include epididymitis and sterility.[mayomedicallaboratories.com]
Scrotal Mass
  • Later, it transpired that he was under investigation for a scrotal mass. Investigations were carried out to ascertain the cause of his symptoms including lymph node biopsy.[ncbi.nlm.nih.gov]

Workup

Pulmonary Infiltrate
  • The baby, who was afebrile, improved on antibiotic therapy but pulmonary infiltrates persisted for several months.[ncbi.nlm.nih.gov]
  • Seite 643 - Short-course empiric antibiotic therapy for patients with pulmonary infiltrates in the intensive care unit. A proposed solution for indiscriminate antibiotic prescription. Am J Respir Crit Care Med. ‎[books.google.de]
Polyps
  • Urethral polyp is one of differential diagnoses for the male patients complain of gross-hematuria and/or hematospermia. However, there have been limited numbers of case reports including infectious etiology.[ncbi.nlm.nih.gov]
Pleural Effusion
  • Ultrasound echographic study and magnetic resonance imaging showed pleural effusion and pelvic ascites.[ncbi.nlm.nih.gov]

Treatment

Prognosis

  • Prognosis Prognosis is excellent with treatment. Patient Education Educate patients about the risks of sexually transmitted diseases and safe sexual practices.[reference.medscape.com]
  • What is the prognosis for a female with chlamydia? As discussed previously, chlamydia infection can progress to pelvic inflammatory disease if untreated, which can have serious consequences.[medicinenet.com]
  • The prognosis is excellent if treatment is initiated early and the entire course of antibiotics is completed. Although treatment failures with primary therapies are quite rare, relapse may occur with alternative therapies.[emedicine.medscape.com]
  • Prognosis Untreated chlamydia will either persist or spontaneously resolve. One study reported a spontaneous resolution rate of 22% [ 18 ].[patient.info]

Etiology

  • Since Chlamydia can be treated with antibiotics, the possible etiologic association with myocarditis has important therapeutic ramifications.[ncbi.nlm.nih.gov]
  • Salpingitis caused by Chlamydia runs a milder clinical course than salpingitis caused by gonococci or other etiology but salpingitis due to Chlamydia is regarded as one of the most important causes of tubal infertility and extrauterine pregnancy.[forskning.ku.dk]

Epidemiology

  • This study aims at evaluating the prevalence of Ct infection in young sexually active asymptomatic women aged 18-25, and characterizing the molecular epidemiology of the different circulating genovars in this population.[ncbi.nlm.nih.gov]
  • Providers should report to the patient's local public health department electronically via EPR, through the Wisconsin Electronic Disease Surveillance System (WEDSS), by mail or fax using the Sexually Transmitted Disease laboratory and morbidity epidemiologic[dhs.wisconsin.gov]
  • Featuring contributions by internationally recognized experts in epidemiology, infectious disease research and chlamydial biology, this book provides up-to-date reviews from a clinical and public health perspective on chlamydia epidemiology and control[books.google.com]
  • Authors : WHO Rationale for the guidelines Since the publication of the WHO Guidelines for the management of sexually transmitted infections in 2003, changes in the epidemiology of STIs and advancements in prevention, diagnosis and treatment necessitate[who.int]
Sex distribution
Age distribution

Pathophysiology

  • Useful For Suggests clinical disorders or settings where the test may be helpful Detection of Chlamydia trachomatis Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test Chlamydia[mayomedicallaboratories.com]
  • Pathophysiology The epidemiology of this disease revolves around sexual contact.[reference.medscape.com]
  • Most of them are involved in the pathophysiology of tubal infertility, birth defects, and miscarriage [ 76 ]. In addition to the inflammatory response, CT infection evokes vigorous local and systemic humoral and cell-mediated immune responses.[intechopen.com]
  • The pathophysiologic mechanisms of chlamydial infection are poorly understood at best.[emedicine.medscape.com]
  • Chlamydia can also be passed from an infected mother to her baby during vaginal childbirth. [21] Pathophysiology Chlamydiae have the ability to establish long-term associations with host cells.[en.wikipedia.org]

Prevention

  • New understanding of sexual risk behaviour is essential for future preventive initiatives.[ncbi.nlm.nih.gov]
  • Centers for Disease Control and Prevention. 2010 Treatment Guidelines, Special Populations. Available online at . Accessed September 2012. (January 13, 2009) Association for Public Health Laboratories.[labtestsonline.it]

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