Presentation
Most patients presenting with chlamydial conjunctivitis will have an associated genital infection (of which they may be unaware). It is important that these patients are referred to genito-urinary medicine clinics for a full STI investigation. [college-optometrists.org]
Presents a more streamlined format to the printed text to help you focus on the clinically actionable information you need everyday. [books.google.com]
Two case reports of patients with laboratory-confirmed inclusion conjunctivitis will be presented. [ncbi.nlm.nih.gov]
Often, symptoms have been present for many weeks or months and have not responded to topical antibiotics. [msdmanuals.com]
Immune System
- Preauricular Adenopathy
Palpation of the preauricular nodes showed adenopathy on the left side only. The patient denied any vaginal irritation or discharge. [clspectrum.com]
Preauricular adenopathy is common, along with conjunctival membranes or pseudomembranes. Patients may have URI symptoms prior to the onset of the conjunctivitis. Treatment is supportive, with cool compresses and artificial tears. [hawaii.edu]
Preauricular adenopathy is common. Constitutional sx include fever, malaise, nausea and vomiting. [hopkinsguides.com]
Eyes
- Conjunctival Injection
injection OU, follicular reaction involving the bulbar conjunctiva and semilunar folds, absence of conjunctival membrane. [webeye.ophth.uiowa.edu]
Clinical features General signs and symptoms of conjunctivitis Conjunctival hyperemia with dilatation of blood vessels (injection) → “pinkeye” Discharge and crust formation Chemosis Foreign-body sensation Photophobia Bacterial vs viral conjunctivitis [amboss.com]
Conjunctival injection, redness and serous or purulent discharge. Preauricular adenopathy is common. Constitutional sx include fever, malaise, nausea and vomiting. [hopkinsguides.com]
Patients demonstrate marked conjunctival injection, conjunctival chemosis (excessive edema), lid swelling and tender preauricular adenopathy. [aafp.org]
- Excessive Tearing
Other classic features are burning, foreign body sensation, excessive tearing, and photophobia. [amboss.com]
Enterovirus : Acute hemorrhagic conjunctivitis (AHC): an epidemic form of highly contagious conjunctivitis characterized by sudden onset of painful, swollen, red eyes, with conjunctival hemorrhaging and excessive tearing. [hopkinsguides.com]
- Unilateral Red Eye
Adult inclusion conjunctivitis presents as a unilateral or less commonly bilateral, red eye with mucopurulent discharge, marked hyperaemia, papillary hypertrophy and a predominant follicular conjunctivitis. [optometry.org.au]
- Conjunctival Disease
Cefpodoxime or cefixime not primarily recommended but may be alternative oral treatment instead of ceftriaxone for uncomplicated GC infection, but no clinical data supporting effectiveness for conjunctival disease. [hopkinsguides.com]
Treatment
Refer adults non-urgently if conjunctivitis lingers after treatment ends Diagnosis often delayed Once proper treatment of inclusion conjunctivitis begins, manifestations usually resolve within weeks without permanent damage to eyes Treatment of trachoma [kellogg.umich.edu]
All three patients completed the oral azithromycin treatment; two of the three patients required a single augmented treatment, whereas the third patient (82 years old) required two augmented treatments. [nature.com]
CONCLUSIONS: A single 1-g azithromycin therapy was as effective as standard 10-day treatment with doxycycline (100 mg twice daily) in the treatment of adult inclusion conjunctivitis. [ncbi.nlm.nih.gov]
Treatment with systemic antibiotics (e.g. single dose of azithromycin or a short course of doxycycline). [college-optometrists.org]
Prognosis
Prognosis: The prognosis is good when the sexual partner is included in therapy. Diabetes 2 Diabetes is a disease that affects the way your body uses food. [alpfmedical.info]
[…] complications from developing, due to the infection Please find comprehensive information on Adult Chlamydial Conjunctivitis regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis [dovemed.com]
Prognosis: Prognosis is usually good if treatment is initiated early and the entire course of antibiotics is completed. Re-infection is very common and is due to non-treatment of infected sexual partners or acquisition from a new partner. [aimu.us]
Prognosis Untreated inclusion conjunctivitis in the newborn persists for 3-12 months and usually heals; however, there may be scarring or neovascularization. [the-medical-dictionary.com]
[…] herpes simplex virus (HSV), varicella-zoster virus ( VZV ), picornavirus, molluscum contagiosum, HIV (highly contagious) Clinical features See “Clinical features” above Epidemic keratoconjunctivitis Herpes simplex conjunctivitis Diagnosis Treatment Prognosis [amboss.com]
Etiology
The etiological agent is CHLAMYDIA TRACHOMATIS whose natural habitat appears to be the genito-urinary tract. Inclusion conjunctivitis is a less severe disease than trachoma and usually clears up spontaneously. [fpnotebook.com]
The etiological agent is chlamydia trachomatis whose natural habitat appears to be the genito-urinary tract. Inclusion conjunctivitis is a less severe disease than trachoma and usually clears up spontaneously. [icd10data.com]
Fifty years later, chlamydial isolation procedures were developed, and studies again demonstrated Chlamydia trachomatis as an etiology of inclusion conjunctivitis of the newborn and the female birth canal as the reservoir. [histopathology-india.net]
References: [1] [2] [3] [4] [5] [6] [7] [8] [9] Bacterial conjunctivitis General Etiology : Staphylococc us aureus (most common in adults), Streptococcal pneumoniae, Haemophilus influenzae, Pseudomonas, Haemophilus, and Moraxella catarrhalis Clinical [amboss.com]
Etiology: Oculogenital infection ( Chlamydia trachomatis serotype D-K) is also caused by direct contact. In the newborn (see neonatal conjunctivitis), this occurs at birth through the cervical secretion. [alpfmedical.info]
Epidemiology
Descriptive Epidemiology 587 Mechanisms and Routes of Transmission 7 Pathogenesis and Immunity 590 Patterns of Host Response 591 Control and Prevention 592 References 593 Suggested Reading 595 Rocky Mountain Spotted Fever Theodore E Woodward and J Stephen [books.google.com]
Mothers of affected infants were found to have inclusions in their cervical epithelial cells, fathers of such infants had inclusions in their urethral cells, and the epidemiology of sexually transmitted chlamydial infections was revealed. [histopathology-india.net]
The epidemiologic patterns described for typical trachoma and typical inclusion conjunctivitis may be mixed. [notesread.com]
References: [18] [19] Non-infectious conjunctivitis Ocular cicatricial pemphigoid ( OCP ) Etiology : autoimmune Epidemiology : predominantly affects older women Pathology : subepithelial blistering with subsequent scarring Symptoms/Clinical features Paroxysmal [amboss.com]
An epidemiological and clinical review. Expert Rev Anti Infect Ther. 2014;12(6):697-704. Mishori R, McClaskey, EL, et al. Chlamydia trachomatis infections: Screening, diagnosis, and management. Am Fam Physician. 2012;86(12):1127-1132. [cancercarewny.com]
Pathophysiology
Pathophysiology: Blindness from trachoma is due to recurrent episodes of active infection. The initial infection is confined to the conjunctival epithelium and triggers an immune response. [eyewiki.aao.org]
Usually chronic progression ( ∼ 10–30 years from symptom onset to end stage) with periods of remission and exacerbation Individual progression on or off treatment is unpredictable (→ long term follow-up is vital) Epidemiology : common in young adults Pathophysiology [amboss.com]
Pathophysiology The epidemiology of this disease revolves around sexual contact. [reference.medscape.com]
Prevention
Descriptive Epidemiology 587 Mechanisms and Routes of Transmission 7 Pathogenesis and Immunity 590 Patterns of Host Response 591 Control and Prevention 592 References 593 Suggested Reading 595 Rocky Mountain Spotted Fever Theodore E Woodward and J Stephen [books.google.com]
Prevention The neonatal infection may be prevented by instilling erythromycin ointment in the conjunctival cul-de-sac at birth. It is not prevented by silver nitrate. Chlamydia is a contagious, sexually transmitted disease. [the-medical-dictionary.com]
Adult Chlamydial Conjunctivitis is a highly infectious condition, which is why you need to do everything possible to prevent it. [stdaware.com]
Adult Chlamydial Conjunctivitis regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE. [dovemed.com]