Presentation
Although the list compiled by these authors contained over 1000 ORFs, which were present in Protochlamydia but were absent in other Chlamydiales, their study did not examine which of these proteins were also present in other bacterial phyla. [doi.org]
Such studies are now required to investigate whether the present findings reflect the position in the lower respiratory tract. A possible confounding factor in the present study is the use of inhaled steroids by asthmatic participants. [erj.ersjournals.com]
According to the CDC, the varied clinical presentation and lack of standardization for diagnostic methods available present unique challenges for accurately identifying C. pneumoniae cases and appropriately treating patients. [arupconsult.com]
CASE: A 32-year-old woman in her fourth pregnancy (16th week of gestation) presented with progressive septicemia after extensive contact with abortive material from her goat flock. Treatment with levofloxacin could not prevent abortion. [ncbi.nlm.nih.gov]
Entire Body System
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Falling
Pneumoniae Germ Type: Bacteria Season: Spring, summer, fall, winter Chlamydophila pneumoniae can cause coughing and a sore throat. [intermountainhealthcare.org]
Overall, 12 (6%) children documented serological evidence of C. pneumoniae infection, spreading across age groups in children, which falls in line with western reports [4], [7], [8], [9] Indian studies are scattered, conducted on small populations, and [ijpmonline.org]
[…] sequencing, however, indicates that 11% of the genes in Candidatus Protochlamydia amoebophila UWE25 and 4% in the Chlamydiaceae are most similar to chloroplast, plant, and cyanobacterial genes. [25] Cavalier-Smith has postulated that the Chlamydiae fall [en.wikipedia.org]
Of all the group-specific proteins identified in this work, 61 chlamydiae loci were determined to be regulated in this manner, and fall into one of the following 4 categories as divided by Nicholson et al. [ 63 ]): early (6-24 hours post infection (hpi [doi.org]
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Pathologist
Mycoplasma pneumoniae or Chlamydophila pneumoniae infections, respiratory Gene Name P1 adhesin (MP), ompA (CP) Test Code MCPPC Division Molecular Microbiology - Bacterial Method Polymerase Chain Reaction External Proficiency Testing College of American Pathologists [sickkids.ca]
"A Review on Chlamydial Diseases in Animals: Still a Challenge for Pathologists?". Veterinary Pathology. 55 (3): 374–390. doi : 10.1177/0300985817751218. PMID 29310550. [en.wikipedia.org]
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Congestive Heart Failure
Congestive heart failure and other noninfectious causes of pulmonary edema Best Tests Subscription Required Management Pearls Subscription Required Therapy Subscription Required References Subscription Required Last Updated: 08/29/2016 [visualdx.com]
Respiratoric
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Respiratory Disorders
Asthma is an important chronic respiratory disorder responsible for a heavy burden of illness 1. [erj.ersjournals.com]
Cardiovascular
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Heart Failure
Congestive heart failure and other noninfectious causes of pulmonary edema Best Tests Subscription Required Management Pearls Subscription Required Therapy Subscription Required References Subscription Required Last Updated: 08/29/2016 [visualdx.com]
Workup
Microbiology
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Legionella Pneumophila
Atypical pneumonia is caused by one of three types of bacteria: Chlamydophila pneumoniae Legionella pneumophila Mycoplasma pneumoniae Chlamydophila Pneumonia This type of pneumonia occurs throughout the year. [homerton.nhs.uk]
Chlamydophila pneumoniae is a causal agent of community-acquired pneumonia and is categorized as an atypical cause of pneumonia, together with Legionella pneumophila and Mycoplasma pneumoniae. Chlamydophila pneumoniae mainly infects adults. [en.vircell.com]
pneumophila concurrently; routine diagnostic tests to identify etiologic agent of outpatient pneumonia in adults are optional (Mandell, Infectious Disease Society of America/American Thoracic Society, 2007) Confirmed by paired serology for C. pneumoniae [arupconsult.com]
Laboratory testing ruled out Streptococcus pyogenes, influenza virus, and Legionella pneumophila as possible infectious etiologies in these cases. [wwwnc.cdc.gov]
The role of atypical pathogens: Mycoplasma pneumoniae, Chlamydia pneumoniae, and Legionella pneumophila in respiratory infection. Infect Dis Clin North Am 1998;12:569-92. 3. Kumar S, Hammerschlag MR. [ijpmonline.org]
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Borrelia Burgdorferi
Could Borrelia burgdorferi be a causal agent of sarcoidosis? Med Hypotheses 1989 ; 30 : 241 –243. Ishige I, Usui Y, Takemura T, Eishi Y. [erj.ersjournals.com]
burgdorferi (0.29, 735aa) CT646 (AAC68823) hypoth, 459aa 0 0 3e-60 1e-68 5e-66 Aspergillus nidulans (5.9, 629aa) CT647 (AAC68824) hypoth, 192aa 2e-98 5e-65 2e-18 1e-15 3e-13 Ciona intestinalis (1.8, 407aa) CT651 (AAC68828) hypoth, 608aa 0 0 1e-97 7e- [doi.org]
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Staphylococcus Aureus
Jackow CM, Cather JC, Hearne V, Asano AT, Musser JM, et al. (1997) Association of erythrodermic cutaneous T-cell lymphoma, superantigen – positive Staphylococcus aureus and oligoclonal T-cell receptor V beta gene expansion. Blood 89: 32-40. [imedpub.com]
aureus (0.041, 154aa) CT147 (AAC67738) hypoth, 1449aa 0 0 3e-71 4e-88 4e-91 Homo sapiens (8e-10, 2442aa) CT178 (AAC67769) hypoth, 404aa 0 0 3e-114 3e-120 4e-122 Thiobacillus denitrificans (2e-15, 830aa) CT195 (AAC67787) hypoth, 363aa 0 2e-147 8e-55 4e [doi.org]
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Vibrio Vulnificus
vulnificus (0.26, 506aa) CT567 (AAC68169) hypoth, 174aa 1e-87 9e-61 5e-24 2e-17 2e-17 Takifugu rubripes (4.1, 1374aa) CT568 (AAC68170) hypoth, 151aa 2e-71 4e-48 2e-22 2e-18 5e-18 Giardia lamblia (1.6, 6739aa) CT577 (AAC68179) hypoth, 119aa 1e-60 3e-48 [doi.org]
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Vibrio Parahaemolyticus
parahaemolyticus (1.8, 92aa) CT079 (AAC67670) hypoth, 147aa 4e-81 1e-71 2e-06 1e-29 1e-29 3e-06, 172aa Leuconostoc mesenteroides (0.11, 263aa) CT131 (AAC67722) PTMP, 1138aa 0 0 0 0 0 3e-33, 1348aa Plasmodium yoelii (0.31, 592aa) CT181 (AAC67772) hypoth [doi.org]
Treatment
Macrolide antibiotics are still the treatment of choice. [ncbi.nlm.nih.gov]
Treatment for Chlamydophila pneumoniae depends on the symptoms and complications. If symptoms are mild, treatment may just mean managing the symptoms until the infection goes away on its own. [intermountainhealthcare.org]
Treatment Antimicrobial Regimen 1. [wikidoc.org]
Treatment : the treatment for atypical pneumonia is based on antibiotic therapies. In acute cases, the therapy includes oral antibiotics. However, severe cases may be treated with intravenous antibiotics and oxygen supplement. [en.vircell.com]
Prognosis
Prognosis of pneumonia caused by Chlamydia pneumoniae is excellent. Hospitalization is uncommon, complications are rare, and most people have no residual deficits. [wikidoc.org]
Characteristics and prognosis of myocardial infarction in patients with normal coronary arteries. Chest. 2000; 117 :333–8. [ PubMed ] [ Google Scholar ] 76. Jantos CA, Krombach C, Wuppermann FN, Gardemann A, Bepler S, Asslan H, et al. [ncbi.nlm.nih.gov]
Etiology
Abstract High affinity to the epithelial lining of the airways makes Chlamydophila pneumoniae a common etiological agent of respiratory tract infections (RTI). [ncbi.nlm.nih.gov]
Since it is difficult to detect C. pneumoniae in clinical practice, specific etiological diagnosis is established only in a minority of cases. [ijpmonline.org]
[…] differential Polymerase chain reaction (PCR) – much more sensitive than culture and serology Serology – atypical pneumonia presentation Order C. pneumoniae, Mycoplasma pneumoniae, and Legionella pneumophila concurrently; routine diagnostic tests to identify etiologic [arupconsult.com]
Potential Infectious Etiologies of Atherosclerosis: A Multifactorial Perspective. Emerging Infectious Diseases, Vol 7, Sept-Oct 2001 Ramirez J, Ahkee A, Ganzel BL, Ogden LL, Gaydos CA, Quinn TC, et al. [wikidoc.org]
Laboratory testing ruled out Streptococcus pyogenes, influenza virus, and Legionella pneumophila as possible infectious etiologies in these cases. [wwwnc.cdc.gov]
Epidemiology
As illustrated in our review, we indeed acknowledge the existing evidence supporting this association in certain but not all geographical areas as well as the epidemiologic and scientific approaches the authors have undertaken. 1, 2 However, there is [bloodjournal.org]
Typical epidemiology: birds excrete infectious organisms in discharge from eyes, beaks, excrement. -- To view the remaining sections of this topic, please sign in or purchase a subscription -- Last updated: November 29, 2015 TY - ELEC T1 - Chlamydophila [hopkinsguides.com]
"Chlamydia pneumoniae and lung cancer: epidemiologic evidence". Cancer Epidemiology, Biomarkers & Prevention. 14 (4): 773–8. doi : 10.1158/1055-9965.EPI-04-0599. PMID 15824142. [en.wikipedia.org]
Parainfluenza 1, 2, 3, 4 Hantavirus Respiratory syncytial virus (RSV) Bordetella pertussis (whooping cough) Adenovirus Hepatitis – viral Myocarditis Myocardial infarction Connective tissue disease Polymyositis Erythema nodosum/erythema multiforme Background Epidemiology [arupconsult.com]
[…] authorities may need to conduct cooperative epidemiologic investigations to control the transmission of C psittaci among humans and birds. [doi.org]
Pathophysiology
Smith KJ, McDonald WI (1999) The pathophysiology of multiple sclerosis: The mechanisms underlying the production of symptoms and the natural history of the disease.Philos Trans R SocLond B BiolSci 354: 1649-1673. [omicsgroup.org]
The pathophysiology of this immunodeficiency is probably multifactorial. [imedpub.com]
Correspondence to: Dr S J Furrows Microbiology Department, University College London Hospitals, Cecil Fleming House, London WC1E 6DB, UK; SFurrowsaol.com Abstract Background: Chlamydophila pneumoniae has been postulated as an aetiological agent in the pathophysiology [jnnp.bmj.com]
Prevention
Treatment with levofloxacin could not prevent abortion. Multiorgan failure requiring catecholamines and artificial ventilation developed in the patient. [ncbi.nlm.nih.gov]
GOVERNMENT OF United States, HEALTH AND HUMAN SERVICES CENTERS FOR DISEASE CONTROL AND PREVENTION THE, Secretary of, Department of Centers of Disease Control and Prevention (Department of Health and Human Services) Original Assignee Centers of Disease [patents.google.com]
Name of Depositor RC Barnes, Centers for Disease Control and Prevention Source Throat swab of pneumonia patient References Barnes RC, et al. Characteristics of atypical chlamydial agents isolated from pneumonia patient in Atlanta, Georgia. [lgcstandards-atcc.org]
Infection control guidance was developed by US Air Force Academy preventive medicine staff and disseminated to all cadets. [wwwnc.cdc.gov]
NIH-funded research has greatly increased knowledge of asthma and led to better treatment and prevention options. Director, Dr. Anthony S. Fauci NIAID Offices, Divisions & Centers [niaid.nih.gov]