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Chlamydophila


Presentation

  • Although the list compiled by these authors contained over 1000 ORFs, which were present in Protochlamydia but were absent in other Chlamydiales, their study did not examine which of these proteins were also present in other bacterial phyla.[doi.org]
  • CASE: A 32-year-old woman in her fourth pregnancy (16th week of gestation) presented with progressive septicemia after extensive contact with abortive material from her goat flock. Treatment with levofloxacin could not prevent abortion.[ncbi.nlm.nih.gov]
  • It has been shown previously that Chlamydophila DNA is present six times more often in the blood of patients with schizophrenia than in the blood of control individuals.[ncbi.nlm.nih.gov]
  • Such studies are now required to investigate whether the present findings reflect the position in the lower respiratory tract. A possible confounding factor in the present study is the use of inhaled steroids by asthmatic participants.[erj.ersjournals.com]
Congestive Heart Failure
  • Congestive heart failure and other noninfectious causes of pulmonary edema Best Tests Subscription Required Management Pearls Subscription Required Therapy Subscription Required References Subscription Required Last Updated: 08/29/2016[visualdx.com]
Sneezing
  • How It's Spread The Chlamydophila pneumoniae bacteria spreads person-to-person through coughs, sneezes, laughs – anything that produces a spray that can be breathed in by someone else..[intermountainhealthcare.org]
Venous Insufficiency
  • Abstract Objective Chronic cerebrospinal venous insufficiency (CCSVI) is a condition associated with multiple sclerosis (MS).[journals.sagepub.com]
  • Keywords Chlamydophila pneumoniae ; Multiple sclerosis ; Chronic cerebrospinal venous insufficiency ; CCSVI; Stenosing venous malformations; Vascular infections ; Venulitis Introduction Recent studies have demonstrated chronic cerebrospinal venous insufficiency[omicsgroup.org]
Heart Failure
  • Congestive heart failure and other noninfectious causes of pulmonary edema Best Tests Subscription Required Management Pearls Subscription Required Therapy Subscription Required References Subscription Required Last Updated: 08/29/2016[visualdx.com]

Workup

Legionella Pneumophila
  • Atypical pneumonia is caused by one of three types of bacteria: Chlamydophila pneumoniae Legionella pneumophila Mycoplasma pneumoniae Chlamydophila Pneumonia This type of pneumonia occurs throughout the year.[homerton.nhs.uk]
  • Chlamydophila pneumoniae is a causal agent of community-acquired pneumonia and is categorized as an atypical cause of pneumonia, together with Legionella pneumophila and Mycoplasma pneumoniae . Chlamydophila pneumoniae mainly infects adults.[en.vircell.com]
  • pneumophila concurrently; routine diagnostic tests to identify etiologic agent of outpatient pneumonia in adults are optional (Mandell, Infectious Disease Society of America/American Thoracic Society, 2007) Confirmed by paired serology for C. pneumoniae[arupconsult.com]
  • Laboratory testing ruled out Streptococcus pyogenes , influenza virus, and Legionella pneumophila as possible infectious etiologies in these cases.[wwwnc.cdc.gov]
  • The role of atypical pathogens: Mycoplasma pneumoniae , Chlamydia pneumoniae , and Legionella pneumophila in respiratory infection. Infect Dis Clin North Am 1998;12:569-92. 3. Kumar S, Hammerschlag MR.[ijpmonline.org]
Borrelia Burgdorferi
  • Could Borrelia burgdorferi be a causal agent of sarcoidosis? Med Hypotheses 1989 ; 30 : 241 –243. Ishige I, Usui Y, Takemura T, Eishi Y.[erj.ersjournals.com]
  • burgdorferi (0.29, 735aa) CT646 (AAC68823) hypoth, 459aa 0 0 3e-60 1e-68 5e-66 Aspergillus nidulans (5.9, 629aa) CT647 (AAC68824) hypoth, 192aa 2e-98 5e-65 2e-18 1e-15 3e-13 Ciona intestinalis (1.8, 407aa) CT651 (AAC68828) hypoth, 608aa 0 0 1e-97 7e-[doi.org]
Vibrio Vulnificus
  • vulnificus (0.26, 506aa) CT567 (AAC68169) hypoth, 174aa 1e-87 9e-61 5e-24 2e-17 2e-17 Takifugu rubripes (4.1, 1374aa) CT568 (AAC68170) hypoth, 151aa 2e-71 4e-48 2e-22 2e-18 5e-18 Giardia lamblia (1.6, 6739aa) CT577 (AAC68179) hypoth, 119aa 1e-60 3e-48[doi.org]
Plasmodium Falciparum
  • falciparum (1.1, 1057aa) CT142 (AAC67733) hypoth, 285aa 3e-155 2e-109 1e-39 9e-50 6e-49 Heterobasidion annosum (5.0, 507aa) CT143 (AAC67734) hypoth, 280aa 3e-165 3e-123 2e-36 9e-55 4e-56 porcine (0.26, 725aa) CT144 (AAC67735) hypoth, 285aa 2e-143 3e-[doi.org]
Polyps
  • Evaluation of Mycoplasma and Chlamydia infection with PCR method and serology in patients with nasal polyps and normal subjects. RJMS. 2009; 15 (60): 133-9 15. Volanen I, Vainionpaa R, Ilonen J, Markula P, Kallio K, Kaitosaari T, et al.[jjmicrobiol.com]
Gliosis
  • Neurodegeneration is a consequence of demyelination, being the pathologic hallmark of MS the demyelinated region, which is referred to as plaque typically consisting of areas of demyelinaion and gliosis around blood vessels [ 20 , 27 , 28 ].[omicsgroup.org]

Treatment

  • Macrolide antibiotics are still the treatment of choice.[ncbi.nlm.nih.gov]
  • Treatment for Chlamydophila pneumoniae depends on the symptoms and complications. If symptoms are mild, treatment may just mean managing the symptoms until the infection goes away on its own.[intermountainhealthcare.org]
  • INTERVENTIONS: Cardiopulmonary resuscitation, extracorporal membrane oxygenation, implantation of an extracorporal cardiac assist device, and antibiotic treatment with erythromycin.[ncbi.nlm.nih.gov]
  • Treatment Antimicrobial Regimen 1.[wikidoc.org]
  • The woman fully recovered after treatment with doxycycline. In the goat herd with which her husband worked Chlamydophila abortus was actively circulating, as shown by positive serology.[ncbi.nlm.nih.gov]

Prognosis

  • Prognosis of pneumonia caused by Chlamydia pneumoniae is excellent. Hospitalization is uncommon, complications are rare, and most people have no residual deficits.[wikidoc.org]
  • Characteristics and prognosis of myocardial infarction in patients with normal coronary arteries. Chest. 2000; 117 :333–8. [ PubMed ] [ Google Scholar ] 76. Jantos CA, Krombach C, Wuppermann FN, Gardemann A, Bepler S, Asslan H, et al.[ncbi.nlm.nih.gov]

Etiology

  • Abstract High affinity to the epithelial lining of the airways makes Chlamydophila pneumoniae a common etiological agent of respiratory tract infections (RTI).[ncbi.nlm.nih.gov]
  • Since it is difficult to detect C. pneumoniae in clinical practice, specific etiological diagnosis is established only in a minority of cases.[ijpmonline.org]
  • […] differential Polymerase chain reaction (PCR) – much more sensitive than culture and serology Serology – atypical pneumonia presentation Order C. pneumoniae , Mycoplasma pneumoniae , and Legionella pneumophila concurrently; routine diagnostic tests to identify etiologic[arupconsult.com]
  • Potential Infectious Etiologies of Atherosclerosis: A Multifactorial Perspective . Emerging Infectious Diseases , Vol 7, Sept-Oct 2001 Ramirez J, Ahkee A, Ganzel BL, Ogden LL, Gaydos CA, Quinn TC, et al.[wikidoc.org]
  • Laboratory testing ruled out Streptococcus pyogenes , influenza virus, and Legionella pneumophila as possible infectious etiologies in these cases.[wwwnc.cdc.gov]

Epidemiology

  • As illustrated in our review, we indeed acknowledge the existing evidence supporting this association in certain but not all geographical areas as well as the epidemiologic and scientific approaches the authors have undertaken. 1 , 2 However, there is[bloodjournal.org]
  • Typical epidemiology: birds excrete infectious organisms in discharge from eyes, beaks, excrement. -- To view the remaining sections of this topic, please sign in or purchase a subscription -- Last updated: November 29, 2015 TY - ELEC T1 - Chlamydophila[hopkinsguides.com]
  • "Chlamydia pneumoniae and lung cancer: epidemiologic evidence". Cancer Epidemiology, Biomarkers & Prevention . 14 (4): 773–8. doi : 10.1158/1055-9965.EPI-04-0599 . PMID 15824142 .[en.wikipedia.org]
  • Parainfluenza 1, 2, 3, 4 Hantavirus Respiratory syncytial virus (RSV) Bordetella pertussis (whooping cough) Adenovirus Hepatitis – viral Myocarditis Myocardial infarction Connective tissue disease Polymyositis Erythema nodosum/erythema multiforme Background Epidemiology[arupconsult.com]
  • Epidemiology of Chlamydia pneumoniae in atherosclerosis . Am Heart J 1999 ; 138: S500 – 503 . Google Scholar Crossref Medline ISI 47. Lindholt, JS, Shi, GP. Chronic inflammation, immune response, and infection in abdominal aortic aneurysms .[journals.sagepub.com]
Sex distribution
Age distribution

Pathophysiology

  • Smith KJ, McDonald WI (1999) The pathophysiology of multiple sclerosis: The mechanisms underlying the production of symptoms and the natural history of the disease.Philos Trans R SocLond B BiolSci 354: 1649-1673.[omicsgroup.org]
  • The pathophysiology of this immunodeficiency is probably multifactorial.[imedpub.com]
  • Correspondence to: Dr S J Furrows Microbiology Department, University College London Hospitals, Cecil Fleming House, London WC1E 6DB, UK; SFurrowsaol.com Abstract Background: Chlamydophila pneumoniae has been postulated as an aetiological agent in the pathophysiology[jnnp.bmj.com]

Prevention

  • Treatment with levofloxacin could not prevent abortion. Multiorgan failure requiring catecholamines and artificial ventilation developed in the patient.[ncbi.nlm.nih.gov]
  • GOVERNMENT OF United States, HEALTH AND HUMAN SERVICES CENTERS FOR DISEASE CONTROL AND PREVENTION THE, Secretary of, Department of Centers of Disease Control and Prevention (Department of Health and Human Services) Original Assignee Centers of Disease[patents.google.com]
  • Name of Depositor RC Barnes, Centers for Disease Control and Prevention Source Throat swab of pneumonia patient References Barnes RC, et al. Characteristics of atypical chlamydial agents isolated from pneumonia patient in Atlanta, Georgia.[lgcstandards-atcc.org]
  • Infection control guidance was developed by US Air Force Academy preventive medicine staff and disseminated to all cadets.[wwwnc.cdc.gov]
  • PREVENTION AND CONTROL: Systematic vaccination with inactivated vaccines of the entire flock is required, including males. This allows vaccination even during pregnancy.[hipra.com]

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