An unusual presentation of chlorpropamide toxicity, presenting as a mixed hepatocanalicular reaction, is reported, along with a review of the literature. [ncbi.nlm.nih.gov]

• Acute Intermittent Porphyria

  Chlorpropamide is dangerous in patients suffering from acute forms of porphyria, especially variegate porphyria, and to a lesser extent acute intermittent porphyria and hereditary coproporphyria. [home.intekom.com]

  Clorpropamida is also used to treat nausea and vomiting, anxiety before surgery, chronic hiccups, acute intermittent porphyria, and symptoms of tetanus. Clorpropamida may also be used for purposes not listed in this medication guide. [ndrugs.com]

  Clorpropamida is also used to treat nausea and vomiting, anxiety before surgery, chronic hiccups, acute intermittent porphyria, and symptoms of tetanus. Clorpropamida may also be used for purposes not listed in Clorpropamida guide. [gmedication.com]

• Congestive Heart Failure

  Alcohol even in moderation Alcohol intoxication Cardiovascular disease predisposing to tissue hypoxia Carry a reliable source of sugar along with you Congestive heart failure Do not drink alcohol Do not drive or operate heavy machinery Exercise caution [tabletwise.com]

• Nausea

  Symptoms include headache, hunger, sweating, irritability, dizziness, nausea, and feeling shaky. [everydayhealth.com]

  Gastrointestinal: Gastrointestinal disturbances are the most common reactions; nausea has been reported in less than 5% of patients, and diarrhea, vomiting, anorexia, and hunger in less than 2%. [rxlist.com]

  Side Effects Nausea, loss of appetite, diarrhea, vomiting, and weight gain may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. [webmd.com]

  Alcohol also interacts with the medication and can cause discomfort and unwanted side effects such as stomach pain, nausea, facial flushing and dizziness. [medicalook.com]

• Skin Rash

  Common side effects of Diabinese include: nausea, loss of appetite, diarrhea, vomiting, weight gain, mild hunger, skin rash, redness, or itching. The most common side effect of Diabinese is low blood sugar ( hypoglycemia ). [rxlist.com]

  Get emergency medical help if you have signs of an allergic reaction ( hives, difficult breathing, swelling in your face or throat) or a severe skin reaction ( fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and [emedicinehealth.com]

  Check with your doctor as soon as possible if any of the following side effects occur: severe skin rash or blistering, peeling skin skin rash or itchy skin symptoms of low blood sugar dizziness drowsiness headache lack of energy nervousness numbness or [medbroadcast.com]

• Fear

  Some physicians initially treat patients having non-insulin-dependent diabetes with oral sulfonylureas because they fear greater compliance problems with insulin therapy. [ncbi.nlm.nih.gov]

• Hyponatremia

  Abstract The incidence and risk factors of chlorpropamide-induced hyponatremia were assessed in diabetic outpatients. [ncbi.nlm.nih.gov]

  Monitor I&O ratio and pattern: Infrequently, chlorpropamide produces an antidiuretic effect, with resulting severe hyponatremia, edema, and water intoxication. [robholland.com]

• Erythroblast

  The aim of this work was to evaluate the toxic effects of the antiviral agent, 3'-azido-3'-deoxythymidine (AZT), the antidiabetic drug, chlorpropamide (CLP), and the heme-analogous compound, protophorphirin IX zinc (II) (ZnPP), on the proliferation of erythroblastic [ncbi.nlm.nih.gov]

• Colitis

  One similar case of chlorpropamide toxicity manifested by jaundice and colitis has been previously reported. It is possible that the sulfonamide moiety of the chlorpropamide was implicated in the development of the colitis. [ncbi.nlm.nih.gov]

The effects of the three meals were investigated by administering each of the meals alone, without the medicinal drug (Treatment I); in Treatment II each meal was administered 30 min following the administration of 250 mg chlorpropamide; in Treatment [ncbi.nlm.nih.gov]

Uses antidiabetic Uses For treatment of NIDDM in conjunction with diet and exercise. [chemicalbook.com]

Abstract An epidemiological study was carried out to compare the prevalence of facial flushing in non-diabetics, patients with insulin dependent diabetes, and patients with non-insulin dependent diabetes in response to 40 ml sherry taken 12 hours after [ncbi.nlm.nih.gov]

In: Mann JI, Pyorala K, Teuscher A (eds) Diabetes and epidemiological perspectives. Churchill Livingstone, Edinburgh and London, pp 147–153 Google Scholar 40. [link.springer.com]

If full precautions had been taken in presecribing chlorpropamide and if old age had been regarded as a contra-indication, the hypoglycaemia might have been prevented in 19 out of the 22 patients. [ncbi.nlm.nih.gov]

[…] to prevent bedsores, according to a new study. [mynetmeds.comprar-medicina.com]

Diabetes Management Tips and Preventing Complications Learn 10 simple ways to better manage your diabetes. See tips for controlling blood sugar, diet and exercise and other helpful... [medicinenet.com]