It typically presents with pain, swelling, and tenderness to palpation. The lesion has a predilection for the metaphysis of long bones of the lower extremity, most commonly in the proximal tibial metaphysis. [ncbi.nlm.nih.gov]

• Cervical Lymphadenopathy

  Figure 1: Extra oral photograph revealed a pre-auricular swelling on the left side of the face Click here to view The head and neck examination was non-contributory, with absence of cervical lymphadenopathy. [jomfp.in]

• Soft Tissue Swelling

  Prominent soft tissue swelling and limited range of motion were noted, corresponding to magnetic resonance imaging findings of lytic changes in the right ring finger metacarpal and proximal phalanx, surrounded by an irregularly enhancing mass with soft [ncbi.nlm.nih.gov]

  Physical examination revealed no visible mass but prominent soft tissue swelling in the anteroposterior dimension. [healio.com]

  Soft tissue swelling around the base of 3rd toe and widening of the webspaces is noted. A needle biopsy was reported as benign cartilaginous tumor. Through a combined dorsomedial and plantar approach the soft tissue component was excised. [faoj.org]

  Less common sites include ribs, vertebrae and the bones of skull and hands. [8], [9] Benign cartilaginous tumors almost always appear benign on radiology with sharp circumscribed borders, intact overlying periosteum and no adjacent soft tissue swelling [jcytol.org]

• Fishing

  In an effort to further define the aberrant 6q13 breakpoint and identify the molecular consequences, a fluorescence in situ hybridization (FISH)-based positional cloning strategy on chondromyxoid fibroma abnormal metaphase and interphase cells using a [ncbi.nlm.nih.gov]

  L.M., D.d.J. and K.S. performed FISH analyses. K.H.N. prepared the manuscript with contributions from all other authors. Competing interests The authors declare no competing financial interests. Corresponding author Correspondence to Karolin H Nord. [doi.org]

• Turkish

  View Article PubMed Google Scholar Başbozkurt M, Ateşalp S, Şarlak AY, Tunay S, Yıldırım Y: Chondromyxoid fibroma [in Turkish]. Deniz Tıp Bülteni. 1993, 26: 95-99. [wjso.biomedcentral.com]

  Chondromyxoid fibroma: an evaluation of 11 patients [in Turkish]. Acta Orthop Traumatol Turc. 2007; 41(1):31-35. Yamamoto T, Mizuno K. Chondromyxoid fibroma of the finger. Kobe J Med Sci. 2000; 46(1-2):29-32. Milliez PY, Thomine JM. [healio.com]

• Plethora

  However, this is very non-specific and can be found in a plethora of other bone lesions. They are benign lesions and malignant degeneration is rare. They are usually treated with curettage which however have a high recurrence rate of 25%. [en.wikipedia.org]

• Hunting

  Declerck GM, Rawlings ID, Hunt AC. Chondromyxoid fibroma in the metacarpal bone of the thumb. Acta Orthop Belg. 1992; 58(2):216-220. Patryn A. Chondromyxoid fibroma of the metacarpal bone [in Polish]. [healio.com]

• Overeating

  We report a case of a 7-year-old white female who presented with acute, progressive bilateral lower extremity weakness over 48 h. [ncbi.nlm.nih.gov]

  There was an over-all rate of recurrence of 27 per cent. With curettage alone there was an 80 per cent recurrence rate, but when curettage was combined with corticocancellous bone-grafting the recurrence rate decreased to 7 per cent. [moh-it.pure.elsevier.com]

  The patient also gave a history of painful swelling over the left preauricular region of 15 days' duration. Swelling was initially about the size of a lemon which had gradually increased over a period of 15 days to the present size of an apple. [pediatricneurosciences.com]

• Ear Discharge

  It was associated with pain in the left ear of 1 month duration, the pain was continuous, dull-aching in nature, and not associated with fever, ear discharge, or diminished hearing in the left ear. [pediatricneurosciences.com]

• Long Arm

  We found a novel unbalanced translocation between the long arms of chromosomes 1 and 9, resulting in loss of 1p. In addition, rearrangements involving the 6q23 and 9q22 regions were also observed. [ncbi.nlm.nih.gov]

  Using single-nucleotide polymorphism arrays, the authors first found—in tumors from two different patients—deletions in the long arm of chromosome 6, with a distal breakpoint immediately upstream of the gene that encodes metabotropic glutamate receptor [stm.sciencemag.org]

  In particular, rearrangement of the long arm of chromosome 6 at bands q13 and q25 was most frequent [ 29 – 38 ]. [diagnosticpathology.org]

• Bony Swelling

  A 45-year-old female was admitted with painless bony swelling in the forehead. Computerized tomography demonstrated a well-defined expansive lesion with a sclerotic margin measuring approximately 3 cm in diameter in the right frontal bone. [ncbi.nlm.nih.gov]

  Typically people present with progressive pain, often long standing and/or bony swelling and restricted range of movement in affected limb 3,12. [en.wikipedia.org]

  swelling and restricted range of movement in affected limb 3,12. [radiopaedia.org]

  The common clinical presentation in cases of skull-bone involvement are headache with bony swelling as in our case, others include neuralgia, facial pain, exophthalmos, convulsions, and diplopia. [6] The imaging features of these lesions are characteristic [pediatricneurosciences.com]

  Patients can suffer from bony swelling, dysarthria, neuralgia, diplopia, facial pain, exophthalmos, headache, polyuria, and polydipsia. [5,6,10] In our case, the patient presented with diplopia, occasional headaches, and dizziness, which is consistent [journals.lww.com]

• Small Foot

  Chondromyxoid fibroma is a rare benign bony tumor classically occurring in the metaphyseal region of the long bones surrounding the knee, but also found with relative frequency in other long bones, the pelvis, ribs, and small foot bones. [ncbi.nlm.nih.gov]

  Classically occurring in the metaphyseal region of the long bones surrounding the knee, but also found with relative frequency in other long bones, the pelvis, ribs, and small foot bones.[2] It accounts for less than 1% of all the primary bone tumors [surgicalcasesjournal.com]

  Since then, approximately 700 cases have been reported in the literature, primarily in long bones and the small bones of the foot. [healio.com]

• Lower Leg Pain

  A 10-year-old female presented with left lower leg pain that had progressively increased over the duration of 1 year. On physical examination, tenderness was elicited on palpation of the distal tibia. Routine laboratory testing was normal. [heighpubs.org]

• Suggestibility

  The histogenesis of chondromyxoid fibroma has not yet been postulated, even though the conventional histology and recent immunohistochemical studies on phenotype of the mesenchymal cells and extracellular matrix components suggested its origin in immature [ncbi.nlm.nih.gov]

  Imaging was suggestive of an expansile lesion involving the squamous part of the left temporal bone with calcifications suggestive of a benign chondroid lesion. [pediatricneurosciences.com]

• Neglect

  The patient was seen by local physician and was neglected with prescription of analgesics. [surgicalcasesjournal.com]

Preoperative tumor workup was performed for our patients. We reviewed and recorded demographic data and the sign and symptoms of patients at presentation to our center. [ncbi.nlm.nih.gov]

An extensive infection workup was negative. (click for larger image) Figure 1: CT scan of the chest with three sagittal sections revealing no evidence of interstitial lung disease or air trapping. [the-rheumatologist.org]

Accurate initial diagnosis of such tumors are important for appropriate treatment. En block surgical resection of the tumor is the cornerstone of treatment. [ncbi.nlm.nih.gov]

The treatment options for recurrent chondromyxoid fibroma of the toe range from total amputation to salvaging a functional toe. [ingentaconnect.com]

On the basis of this experience, we believe that thorough curettage combined with corticocancellous bone-grafting remains the treatment of choice for patients with chondromyxoid fibroma. [moh-it.pure.elsevier.com]

This shall facilitate better treatment approaches and prognosis. This case is the first reported case of involvement of the zygomatic arch in a pediatric patient. [jomfp.in]

Prognosis The prognosis is excellent. Cytogenetics Morphological Karyotypes of 12 cases are reported in the literature. Complex cytogenic abnormalities are reported. [atlasgeneticsoncology.org]

[…] this highly lauded three-volume reference provides an interdisciplinary approach to the diagnosis, treatment, and management of head and neck diseases, including the incidence, etiology, clinical presentation, pathology, differential diagnosis, and prognosis [books.google.com]

[…] macrophages and monocytes No bone osteoid No matrix calcification Treatment Extra-capsular marginal excision yields almost no recurrence In rare occasions of soft tissue invasion, wide excision is necessary If skeletally immature, wait until maturity Prognosis [orthopaedicsone.com]

Treatment and prognosis They are benign lesions and malignant degeneration is rare. There is a high rate of reported recurrence (up to 80%) with curettage alone, with lower rate (~20%) with bone grafting. [radiopaedia.org]

Updated, reorganized, and revised throughout, this highly lauded three-volume reference provides an interdisciplinary approach to the diagnosis, treatment, and management of head and neck diseases, including the incidence, etiology, clinical presentation [books.google.com]

To date, no definite etiologies have been documented. It is known that approximately 75% of the total cases of CMF affect the bones of the lower extremities. In particular, it occurs most frequently in the tibia and femur around the knee joint [3]. [surgicalcasesjournal.com]

A study by Romeo et al examined the DNA microarray of chondromyxoid fibroma and demonstrated that CMFs could be differentiated from other cartilaginous tumors. [8] Etiology As is the case with most bone tumors, no specific cause is known for CMF. [emedicine.medscape.com]

Patient Population: Prevalence and Epidemiology Knee // Shoulder & Elbow // Hip // Spine // Foot & Ankle // Hand & Wrist Fragility Fractures: Diagnosis and Treatment Shoulder & Elbow The Characteristics of Surgeons Performing Total Shoulder Arthroplasty [mdedge.com]

As with all rare lesions, reported epidemiology varies: age: most commonly diagnosed before 30 years of age (~75%), mostly during second and third decades 1,12-15 full reported range from 3 to 70 years of age gender: conflicting data 2, 12,18 some series [radiopaedia.org]

Introduction A rare and benign chondrogenic lesion characterized by variable amounts of chondroid, fibromatoid and myxoid elements Epidemiology demographics more common in males most common in second and third decades of life may affect patients up to [orthobullets.com]

Epidemiology Chondromyxoid fibroma is a very rare neoplasm accounting for less than 1% of all bone tumours, and less of 2% of all benign bone tumours. [atlasgeneticsoncology.org]

Epidemiology CMFs account for fewer than 1% of primary bone tumors in the United States. CMFs are becoming less frequently diagnosed, and thus, the current frequency is much lower than 1%. [emedicine.medscape.com]

Epidemiology demographics more common in males most common in second and third decades of life may affect patients up to 75 years old location long bones (ie. tibia, distal femur) often affects metaphyseal (proximal tibia) regions pelvis feet or hands Pathophysiology [orthobullets.com]

Pathophysiology Grossly, CMFs are firm, grayish-white masses that are sharply demarcated; they are lobulated or pseudolobulated. Their appearance can mimic that of fibrous tissue or hyaline cartilage. [emedicine.medscape.com]

A quick and accurate diagnosis of chondromyxoid fibroma can prevent unnecessary treatment that could be harmful to the patient. [ncbi.nlm.nih.gov]

This will prevent amputation of the toe and will give cosmetic success to the patient No References No Citations No Supplementary Data No Article Media No Metrics Document Type: Research Article Affiliations: 1: Department of Orthopedics, Kasturba Medical [ingentaconnect.com]