Chondrosarcoma is a malignant neoplasm that predominantly is made of cartilage. It occurs most frequently in long bones, the pelvic girdle and the scapula. Chondrosarcoma is the second most frequent primary malignant tumor of bone.
The preliminary signs of chondrosarcoma involve dull and deep pain in the affected area which is usually experienced in the night hours. The mean time from the diagnosis of chondrosarcoma from the onset of pain is usually 19.4 month in low grade tumors and much faster in high grade once .
In addition, there may be swelling accompanied by tenderness in the affected area. One of the major factors that distinguish bone cancer from other type of bone disorders is that there is persistent pain in the affected area which is generally felt during night. Another factor that needs mention is that individuals with chondrosarcoma often present with fractures after a minor fall or accident. This one feature is important for distinguishing bone cancer from other disorders of the bone.
The following are the diagnostic procedures employed for detecting chondrosarcoma:
The type of treatment employed depends on the nature, size and location of the tumor. The grade at which the cancer is detected also greatly affects the type of treatment method to be employed. The following methods are applied for treating chondrosarcoma:
Prognosis of chondrosarcoma greatly depends on how early the cancer was detected and treatment initiated. When individuals are diagnosed during the grade I of the disease, prognosis is favorable and the survival rate 5 years after proper treatment is 90%. However, in those when the tumors have become aggressive, the prognosis is poor with only 10% patients surviving the treatment period.
There are high chances that the tumors develop back and therefore it is advised that regular checkup be carried out to detect early signs of new tumor development.
Complications can develop when the cancer has not been diagnosed in the initial stages. As a result, it can metastasize to other parts of the body. In addition, nerve dysfunction can also develop in patients with chondrosarcoma.
The exact cause that triggers the development of chondrosarcoma is unknown. It is however believed that chondrosarcoma may be present as a secondary condition in individuals with other medical illness such as:
Chondrosarcoma may also affect some children who have received either chemotherapy or radiation therapy for treatment of other types of cancer. Some genetic studies also suggests that chondrosarcoma is associated with genetic anomalies like the loss of heterozygosity in many gene loci .
Chondrosarcoma is a rare form of cancer affecting about 600 patients in United States each year. This form of cancer accounts for about 20 to 27% of malignant bone tumors . It affects more males than females, with a male to female ratio of 1.5:1.
Chondrosarcomas are classified into 2 types depending on their source of origin: Primary and secondary. Primary chondrosarcoma occurs spontaneously unlike secondary type that develops as a result of other associated disease conditions. Chondrosarcoma has also been divided into various grades depending on the extent of spread of the disease.
Grade I chondrosarcoma develops at slow rate and is less aggressive in nature. The malignant cells appear similar to those of normal cells of cartilage tissues. Grade II and III are characterized by rapid growing tumor cells which are more aggressive in nature . The cells can appear abnormal and can spread to the neighboring sites such as lymph nodes and other organs. Grade IV chondrosarcoma is defined as anaplastic tumors having abnormal growth pattern.
So far, no guidelines have been formulated to prevent chondrosarcoma. However, if individuals can recognize unusual signs and symptoms and seek medical help then the cancer can be treated at the initial stages. This can help prevent the spread of the cancer to other parts of the body and improve the life expectancy rate.
Chondrosarcoma is a type of cancer that develops in the bones and joints. It is a rare form of cancer and usually affects adults aged 40 years and above. Chondrosarcoma can affect any part of the body that contains cartilages; but primarily begins with development of tumor cells in the arms, legs and or pelvis . Chondrosarcoma may be classified as primary and secondary depending on its source .
Chondrosarcoma is a rare form of bone cancer that develops in the bone and joints. Males more commonly fall prey to such type of cancer. Adults aged 40 years and above are more prone to develop chondrosarcoma. The common areas of tumor development include areas of arm, legs and pelvis.
There are two type of chondrosarcoma: primary and secondary. The exact cause that triggers the development of the primary type is not yet known. However, secondary chondrosarcoma is thought to develop as a result of certain types of disease conditions.
The tumors cells are large in size and measures more than 5 cm. Individuals usually experience a dull and deep pain in the affected area during night. In addition, the patients also complain of inflammation and tenderness in the areas that do not go away with medication.
The condition is diagnosed using bone X-ray that helps in identifying the tumor locations. Imaging studies such as CT scan and MRI help in detection of the spread of the cancer to other parts of the body. Biopsy of the tumor cells is done to analyze the nature of the cells. Bone scan may also be required as it provides additional information about the tumor cells.
Surgery is often the first line of treatment followed by proton therapy to destroy the cancer cells without affecting the healthy tissues of the body.