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Choroid Plexus Papilloma

Choroid Plexus Carcinoma


  • In this case report, we describe dysphonia as an uncommon presentation of a rare posterior fossa tumor. To our knowledge, a case of choroid plexus papilloma presenting with dysphonia has not been described before.[ncbi.nlm.nih.gov]
Multiple Congenital Anomalies
  • The authors describe the case of a child who presented with hydrocephalus and phenotypic features characteristic of a multiple congenital anomalies/mental retardation syndrome.[ncbi.nlm.nih.gov]
  • A Caucasian female previously diagnosed with anorexia nervosa was referred by psychiatric services to the general medical team.[ncbi.nlm.nih.gov]
  • The patient was a 5-year-old girl, who presented with a 1-week history of fever and numbness of the right lower limb.[ncbi.nlm.nih.gov]
  • Choroid plexus papilloma revealed by nontraumatic cerebrospinal fluid (CSF) rhinorrhea has only been described 5 times, to our knowledge, in the literature.[ncbi.nlm.nih.gov]
Back Pain
  • The authors report the case of a 49-year-old man who presented with back pain 19 years after resection of a posterior fossa choroid plexus papilloma.[ncbi.nlm.nih.gov]
Joint Stiffness
  • Characteristics include red or dark patches on the skin; burning, itching, swelling, hardening, and tightening of the skin; yellow spots on the whites of the eyes; joint stiffness with trouble moving or straightening the arms, hands, legs, or feet; pain[emedicine.com]
Low Back Pain
  • Seven years later, she was re-admitted with low back pain. MRI showed multilobulated tumor at the lumbosacral subarachnoidal space with histopathological diagnosis of CPP.[ncbi.nlm.nih.gov]
Progressive Loss of Vision
  • Six months later, he came to us with progressive loss of vision due to raised intracranial pressure. The lesion may not be detected on CT scans and MRI scan is the imaging modality of choice.[ncbi.nlm.nih.gov]
Facial Pain
  • The patient's facial pain gradually resolved. Involvement of the trigeminal nucleus in the brainstem by the cerebellopontine angle tumour is suggested as the possible cause for trigeminal neuralgia in this case.[ncbi.nlm.nih.gov]
Psychomotor Retardation
  • Most patients exhibit CNS manifestations, including psychomotor retardation, seizures, hypotonia, and ataxia. A 6-year-old girl with hypomelanosis of Ito was referred to the authors' hospital with bilateral tumors in the lateral ventricles.[ncbi.nlm.nih.gov]
Visual Hallucination
  • During admission her vomiting worsened and she developed visual hallucinations and confabulation. Neurological examination demonstrated cerebellar signs and bilateral papilloedema on fundoscopy.[ncbi.nlm.nih.gov]
  • This 60-year-old woman was admitted to the hospital because of a 1-year history of sacral pain, rectal and urinary bladder retention, and paradoxical episodic incontinence.[ncbi.nlm.nih.gov]
  • Older people may have headaches, double vision, poor balance, urinary incontinence, personality changes, or mental impairment. In babies, it may be seen as a rapid increase in head size.[howlingpixel.com]
  • A 31-year-old female presented with amenorrhea and intermittent galactorrhoea, with no visual complaints in the last 2 years.[ncbi.nlm.nih.gov]
  • A 51-year-old female presented with a rare case of choroid plexus papilloma originating in the sella turcica manifesting as headaches that was not readily distinguishable preoperatively from pituitary adenoma.[ncbi.nlm.nih.gov]
Morning Headache
  • Case Description: A 21-year-old man with past medical history of asthma presented to us with the chief complaint of morning headache for one month.[file.scirp.org]
Cerebellar Ataxia
  • We present a case of a 54-year-old male manifesting slurred speech,nystagmus and cerebellar ataxia.[webview.isho.jp]
Generalized Seizure
  • A case of a 13-month-old male infant with progressive increase in head circumference, neurodevelopmental delay, and episodic generalized seizures is reported.[ncbi.nlm.nih.gov]
Progressive Macrocephaly
  • A 5-month-old male infant presented with progressive macrocephaly, vomiting, and convulsions. A lesion in the posterior third ventricle was detected on brain MRI.[ncbi.nlm.nih.gov]


  • After doing the workup for primary, he underwent sub-occipital craniotomy, and gross total excision. The tumor was greyish, soft, suckable, and very vascular; gross total excision was done.[ruralneuropractice.com]
  • Clinical presentationThe patient is a 37 year old woman referred from anoutside hospital for workup of an intracranial mass. 3.[de.slideshare.net]
  • This workup often necessitates a battery of immunohistochemical studies. Transthyretin and/or S100 expression is supportive evidence for a choroid plexus neoplasm, although, unfortunately these stains are not 100% reliable.[r-radiology.com]
Blood Culture Positive
  • Her laboratory results were significant for an absolute neutrophil count of 0/µL and blood cultures positive for Capnocytophagia species. She was supported with broad spectrum antibiotics and myeloid growth factors.[ncbi.nlm.nih.gov]


  • Total surgical resection is the treatment of choice for choroid plexus tumors. However, the hypervascular nature of such lesions imposes challenges to the surgical treatment.[ncbi.nlm.nih.gov]
  • Treatment planning included placement of a ventriculoperitoneal shunt to treat hydrocephalus and to allow the child to grow prior to resection.[inovaideas.org]


  • This case highlights the available treatment and good prognosis that is possible with Choroid plexus papilloma.[ncbi.nlm.nih.gov]
  • Immunophenotype cytokeratins: positive (especially CK7) vimentin : positive transthyretin usually positive also found in normal choroid plexus better prognosis if positive 10 S100 variable better prognosis if positive 10 KIR7.1 usually positive and specific[radiopaedia.org]
  • Complete resection of this malignant tumor is the primary goal of treatment since it allows best chance of survival and improves the overall prognosis [1] [4] [5].[file.scirp.org]


  • One theory of the etiology involves the presence of simian vacuolating virus No. 40 (SV40)–related viral DNA. Pathology: They may arise wherever a choroid plexus exists. Tumoral distribution varies between pediatric and adult patients.[thamburaj.com]
  • Etiology CPPs arise from the single layer of cuboidal epithelial cells lining the papillae of the choroid plexus.[emedicine.medscape.com]
  • […] factori fumatul ţigarete ţigări de foi pipă mestecatul prizatul Consumul de alcool Factori chimici azbest crom nichel arsenic formaldehidă Alţi factori radiaţii ionizante sindromul Plummer-Vinson virusul Epstein-Barr virusul HPV As with lung cancer, many etiologic[slideplayer.com]
  • There is no significant sex predilection. [1] Etiology Although the vast majority of choroid plexus tumors are sporadic, hereditary factors appear to play a role in the development of some choroid plexus papillomas and carcinomas.[r-radiology.com]


  • Epidemiology Frequency CPPs are rare, comprising less than 1% of brain tumors in patients of all ages.[emedicine.medscape.com]
  • Epidemiology Choroid plexus papilloma accounts for less than 1% of all brain tumors, and about 2-4% of those that occur in children. 10-20% of all choroid plexus papillomas aise in the first year of life. The average incidence is 0.3 per 1,000,000.[prod.wiki.cns.org]
  • Hankinson , Pediatric choroid plexus tumors: epidemiology, treatments, and outcome analysis on 202 children from the SEER database, Journal of Neuro-Oncology , 2015 , 121 , 1, 201 CrossRef 3 Annalisa Passariello , Maria Tufano , Pietro Spennato , Lucia[onlinelibrary.wiley.com]
  • Jump to navigation Jump to search Epidemiology [ edit ] 0.5% intracranial neoplasms 10-20% intracranial neoplasms in 70% of choroid plexus tumors occur in pts Histology [ edit ] Choroid plexus papillomas are WHO grade I.[en.wikibooks.org]
  • The relatively small number of CPC cases in the literature, coupled with the lack of relevant epidemiological data and controversies about their clinical and pathological diagnosis makes it difficult to establish a standardized therapeutic approach in[journals.plos.org]
Sex distribution
Age distribution


  • The challenges in this situation are to recognize CSF leak, to rapidly understand the pathophysiology of the leak, and to choose the best treatment strategy in emergency.[ncbi.nlm.nih.gov]
  • Contents 1 Pathophysiology 2 Frequency and age affected 3 Signs and symptoms 4 Surgical treatment 5 See also 6 Additional images 7 References 8 External links Pathophysiology[edit] The tumor is neuroectodermal in origin and similar in structure to a normal[theinfolist.com]
  • Pathophysiology The tumor is neuroectodermal in origin and similar in structure to a normal choroid plexus . They may be created by epithelial cells of the choroid plexus .[howlingpixel.com]
  • Pathophysiology Neuroectodermal origin: The structure is similar to normal choroid plexus, and it is formed of epithelial cells.[ispn.guide]
  • TWIST-1 is involved in the p53 tumor suppressor pathway as an inhibitor. [19] Pathophysiology Symptoms from choroid plexus tumors generally result from secretion of CSF by tumor cells, leading to an increased amount of fluid and, eventually, to hydrocephalus[emedicine.medscape.com]


  • We recommend precise evaluation of intracranial cystic lesions to prevent wrong diagnosis and operation. Total resection of all enhancing nodules in cystic choroid plexus papilloma is proposed to warrant total cure of tumor.[ncbi.nlm.nih.gov]
  • They bring together our team of multidisciplinary experts to deliver a coordinated approach to neuroscience, from research and prevention to treatment and post-treatment care.[northwell.edu]
  • In this particular case, two lines of chemotherapy had failed, and poor marrow reserve secondary to craniospinal radiotherapy in an adult patient (36 Gy of craniospinal irradiation and 54 Gy to the cranium) prevented further delivery of cytotoxics.[pagepress.org]
  • Chemotherapy contributes to long-term survival, but it can not prevent recurrence [ 8 ]. Bleggi-Torres et al. reported 15 cases of CPC and the oldest patient of his series is 22 years old [ 9 ].[panafrican-med-journal.com]
  • Radiation therapy : This process destroys cancer cells and prevents others from growing.[aurorahealthcare.org]

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