Two cases of pituitary necrosis was presented, one occurring post partum in an otherwise normal gland, the other in a large chromophobe adenoma. [ncbi.nlm.nih.gov]

HISTORY Similarly, most patients with a gastro-enterological and neurological problem will present with a specific Present history symptom - diarrhoea, or tremor - which will direct attention to that organ system. [books.google.com]

• Pneumonia

  This report deals with a 1.5-year-old male infant terminating in viral pneumonia and "diabetes insipidus". [ncbi.nlm.nih.gov]

  Abstract This report deals with a 1.5-year-old male infant terminating in viral pneumonia and "diabetes insipidus". [pubmed.ncbi.nlm.nih.gov]

Size A MICROadenoma is less than 1 cm and is often an incidental finding on an MRI of the brain done for other reasons, like workup of a headache. [neurosurgerybasics.com]

[…] adenomas show numerous enlarged mitochondria with loss of cristae and presence of electron dense tubular structures (Brain Pathol 2012;22:443) Molecular / cytogenetics description No specific molecular characteristics in routine clinical diagnostic workup [pathologyoutlines.com]

While a majority of patients with endogenous Cushing syndrome have thyrotrophic adenomas (called Cushing Disease - see below), other tumors should also be considered as part of the endocrinologic workup, including adrenal tumors and especially ACTH-secreting [eyewiki.aao.org]

Endocrine Testing Apparently nonfunctioning adenomas may be associated with abnormal results on serum endocrine studies; these studies should be done as part of the comprehensive workup of an apparently nonsecretory lesion. [pituitaryadenomas.com]

• Enlarged Sella

  Abstract A 50-year-old man with bitemporal hemianopsia and an enlarged sella turcica was found to have hyperthyroidism with elevated serum thyrotropin levels (17 mμg per milliliter) measured by radioimmunoassay. [nejm.org]

  ( PMID 945663 ), not uniformly accepted Grade 0: Intrapituitary microadenoma with normal sellar appearance Grade I: Normal-sized sella (15 × 12 mm) with asymmetry of the floor Grade II: Enlarged sella with an intact floor Grade III: Localized erosion [en.wikibooks.org]

  On MRI non secretory pituitary adenomas are usually associated with an enlarged sella turcica. [pituitaryadenomas.com]

Adrenalectomy performed in the treatment of Cushing's disease may be followed by skin pigmentation and an enlarging pituitary tumour (Nelson's syndrome), changes which are commonly attributed to the removal of the negative feed-back mechanism. [ncbi.nlm.nih.gov]

The medical treatment of Cushing’s disease: effectiveness of chronic treatment with the dopamine agonist cabergoline in patients unsuccessfully treated by surgery. Journal of Clinical Endocrinology and Metabolism 94: 223-230, 2009. [csrf.net]

Pituitary tumors n=475 (59%), systemic disease treatment by inducing hypopituitarism n=365 (41%). [en.wikibooks.org]

Abstract Renal oncocytoma, conventional RCC (granular cell type) and chromophobe RCC have different prognosis. Sometimes differentiation between them is difficult in HandE slides. [ncbi.nlm.nih.gov]

Prognosis Recurrent symptoms requiring further intervention is relatively common, with 18% of patients with non-functioning tumors and 25% of patients with prolactinomas eventually needing further treatment 6 . [radiopaedia.org]

Prognosis The anatomic extent of the disease represented by stage of disease is the single most important indicator of prognosis in RCC. [atlasgeneticsoncology.org]

Identification of these subtypes could lead to separation of hepatocellular carcinomas into discrete groups with unique underlying genetic changes, prognosis, or therapeutic responses. [nature.com]

CONCLUSIONS Chromophobe RCC normally has an excellent prognosis after radical surgery, even when it is locally advanced. It is necessary to be aware of the possibility of underlying syndromes. [urotoday.com]

In none of these cases, however, was the diagnosis of an ACTH-secreting chromophobe adenoma established at the outset, and the present evidence favoring a pituitary etiology is based on retrospective reasoning and demonstration of abnormally high levels [nejm.org]

Etiology A specific factor in the etiology of RCC is not known at the moment, although a number of dietary, environmental factors, hormonal, celllular and genetic factors associated with increased risk. [atlasgeneticsoncology.org]

[…] of somatotrophs, lactotrophs and thyrotrophs SF-1 (steroidogenic factor 1): gonadotroph cell differentiation T-PIT (T-box family member TBX19): proopiomelanocortin (POMC) lineage with differentiation of corticotrophs (Acta Neuropathol 2017;134:521) Etiology [pathologyoutlines.com]

The etiology and pathophysiology of CH are unknown. [jmedicalcasereports.biomedcentral.com]

If the presenting symptom is sudden monocular visual loss, a pituitary adenoma may be acutely missed, as other more common etiologies are evaluated. [eyewiki.aao.org]

Epidemiology [ 1 ] Pituitary tumours account for 10% to 25% of all intracranial neoplasms. Adenomas account for the largest portion of pituitary neoplasms (estimated at approximately 17%). Only a minority of adenomas are symptomatic. [patient.info]

[…] cell borders, finely reticular pale cytoplasm, perinuclear halos and wrinkled raisinoid nuclei First described in 1985 ( Virchows Arch B Cell Pathol Incl Mol Pathol 1985;48:207 ) Cell of origin: distal convoluted tubules and cortical collecting ducts Epidemiology [pathologyoutlines.com]

Epidemiology ChRCC comprise ~5% of all renal cell carcinomas. Most tumors are sporadic, with a slight male predilection. Pathology ChRCC tumors can vary in size and have a tan to brown cut surface. [atlasgeneticsoncology.org]

Jump to navigation Jump to search Pituitary Adenoma Epidemiology [ edit ] Comprise ~10% of intracranial tumors On autopsy found in 5-25% Male:female 1:1 Majority present between 30-50 years old Genetic predisposition in MEN-1 Benign histologically Nonsecretory [en.wikibooks.org]

The etiology and pathophysiology of CH are unknown. [jmedicalcasereports.biomedcentral.com]

[…] pituitary gland C75.1 Sites Majority occur in sella turcica within the adenohypophysis / anterior pituitary lobe Rare examples occur in extrasellar region on pituitary stalk Rare prolactinomas as part of ovarian teratoma (Endocr Pathol 2014;25:321) Pathophysiology [pathologyoutlines.com]

Our growing understanding of pituitary pathophysiology has led to a steady diminution in the number of pituitary adenomas considered to be nonsecretory. [pituitaryadenomas.com]

The histogenesis still remains controversial, and ongoing research is required to understand its pathophysiology and draw any firm conclusions to assist and guide clinical practice. [edmcasereports.com]

The exact pathophysiology of this phenomenon is unknown; however, as most of these lesions involve the chiasm and/or diencephalon, many have proposed that disruption of visual and vestibular input contribute to this pathology. [eyewiki.aao.org]

Prevention There are no known ways to prevent pituitary cancer, but there are ways to lower your chances of getting any kind of cancer, and to kill it early if you do get cancer. Such methods include: 1. [slideshare.net]

There is no way to prevent kidney cancer from forming. It is more a matter of avoiding risk factors, such as unhealthy diet and smoking. [my.clevelandclinic.org]

At present, most patients are treated as having a clinically nonfunctioning adenoma, and the therapeutic goals are restoration of visual deficits, preservation of pituitary function, and prevention of recurrence. [15] Null cell adenomas and oncocytomas [emedicine.medscape.com]

Immunoreactions were developed using a non-biotin, highly sensitive system (Envision peroxidase detection system, DAKO, Carpinteria, CA, USA) preventing possible false-positive staining due to endogenous biotin present in the tissues. [nature.com]

Bromocriptine administration is noninvasive and may reduce tumor size or may retard or prevent potential tumor growth; therapeutic benefits depend on its continued use. [glowm.com]