The present study suggests that genotoxic damage results from exposure to chronic low doses of ionizing radiation in nuclear medicine departments. [ncbi.nlm.nih.gov]

• Multiple Congenital Anomalies

  Mokhtar ABSTRACT: Karyotyping was done in 137 children suspected of having chromosomal abnormalities such as genetically uncertain syndromes, multiple congenital anomalies, short stature, dysmorphic features, unclassified mental retardation and Down syndrome [emro.who.int]

  The Perlman syndrome: familial renal dysplasia with Wilms tumor, fetal gigantism and multiple congenital anomalies. Am J Med Genet1984;19:195–207. Greenberg F, Stein F, Gresik MV, Finegold MJ, Carpenter RJ, Riccardi VM, Beaudet AL. [jmg.bmj.com]

• Keratosis

  […] chromosome and chromatid types) and mitotic index were analyzed from the lymphocytes of 25 cases of Bowen's patient which was compared to matched control from the individuals with arsenic induced non-cancerous skin lesions such as raindrop pigmentation, keratosis [ncbi.nlm.nih.gov]

Significant decreases in MI and PI were concentration dependent at both treatment times. The decrease in NDI was also concentration-dependent at 48-h treatment period. [ncbi.nlm.nih.gov]

Prognosis : Only 5–10% of patients survive past 12 months of age. References: [3] [6] [8] Down syndrome (trisomy 21) [amboss.com]

Prognosis The prognosis is variable and depends on the severity of the disease. The infant mortality rate is relatively low ( 4%); in adults mortality is higher than that of the rest of the adult population. [orpha.net]

The authors point out that some of the chromosomal abnormalities have revealed targets for cancer treatment, and others have clinical application in the diagnosis of certain types of neoplasms and in the formulation of a prognosis. [nejm.org]

The assay may be used to dichotomize CLL (the 13q-, 12, or normal genotype group versus the 11q- or 17p- group) and may be used as an aid in determining disease prognosis in combination with additional biomarkers, morphology, and other clinical information [molecular.abbott]

- Bertell, Rosalie: No immediate danger : Prognosis for a radioactive earth. 1985. - 435 s. - ISBN 0-7043-3934-X Chadwick, James: Radioactivity and radioactive substances; an introduction to the study of radioactive substances and their radiations [fredsakademiet.dk]

Currently, no teratogenic agent, environmental factor, or defective genes have been recognized as etiologic factors for this type of urogenital malformation. [ncbi.nlm.nih.gov]

DiGeorge syndrome, velocardiofacial syndrome, cardiofacial syndrome) but are now known to be etiologically identical and are referred to as 22q11.2 DS. [orpha.net]

In a craniofacial clinic it may be important to identify subtle dysmorphism and DD to establish a chromosomal etiology. Conflicts of Interest The authors declare that they have no conflicts of interest. [hindawi.com]

Thus, cytogenetic analysis of spontaneous miscarriages is essential to establish the etiology of fetal losses and to assess patients with risks of recurrence in future pregnancies. [karger.com]

Karyotype assessment is important to consider in all epilepsies where the etiology is uncertain as dysmorphic features may be subtle or not apparent. Karyotype examination should be extended to 50-100 mitoses to exclude mosaicism. [epilepsydiagnosis.org]

In the past, epidemiological studies indicated a possible correlation between the exposure to ELF fields and cancer. [ncbi.nlm.nih.gov]

Neoplasms 482 3032 Lymphoid Neoplasms 484 304 Solid Tumors 487 305 Molecular Cytogenetics 488 306 Future for Cytogenetics in Cancer Investigations 492 Chromosomal Aberration in Peripheral Blood Lymphocytes of Healthy Subjects and Risk of Cancer 494 312 The Epidemiologic [books.google.com]

The use of biological markers as predictive early-outcome measures in epidemiological research. In: P. Toniolo, P. Boffetta, D. E. G. Shuker, N. Rothman, B. Hulka, and N. Pearce (eds.), Application of Biomarkers in Cancer Epidemiology, pp. 281–289. [cancerres.aacrjournals.org]

Descriptive epidemiology of congenital heart disease in Northern England. Paediatr Perinat Epidemiol, 23 (2009), pp. 58-65 [25] O. Baspinar, S. Karaaslan, B. Oran, T. Baysal, A.M. Elmaci, A. Yorulmaz. [analesdepediatria.org]

Chromosome 21 and Down syndrome: From genomics to pathophysiology. Nature Reviews Genetics 5, 725–738 (2004) doi:10.1038/nrg1448 (link to article) FitzPatrick, D. R. [nature.com]

For the purpose of biological dosimetry after partial body exposure, an extension of the lymphocyte culture time is suggested at least for doses or 3.0 Gy of 200 kV X-rays and or 0.5 Gy of or 2.1 MeV neutrons in order to prevent a systematic underestimation [ncbi.nlm.nih.gov]

Now 5, he was born with a genetic chromosomal abnormality that prevents his standing. Its high definition imaging may also detect other less common chromosomal abnormalities. [diki.pl]

The study highlights the important role of antioxidants as a preventive tool decreasing the level of DNA oxidation, which is a potential cause of human cancer. Received: 24 August 2006 Accepted: 14 December 2006 Back [omfi.hu]

For some chromosomal conditions, a cardiologist will prescribe medicines to prevent dilation (enlargement) of your child’s aorta and other blood vessels. [rileychildrens.org]

In early miscarriage, chromosomal errors can prevent a fetus or embryo from developing normally. [verywellfamily.com]