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Chronic Angina

Presentation

STEMI: presents with typical symptoms as mentioned above with ST elevations noted on ECG; generally caused by acute plaque rupture and complete obstruction of culprit vessel and may present prior to laboratory detection of troponin. [unboundmedicine.com]

Typical presentation Central or left sided chest discomfort May radiated to jaw, arm epigastrium – like ACS pain Can vary from mild to severe Usually described as a “tight” or “crushing” sensation Dyspnoea may or may not be present Usually result from [almostadoctor.co.uk]

Acute and Stable Ischemic Heart Disease: Clinical Presentation Number: 1171-442 2018 American College of Cardiology Foundation [onlinejacc.org]

Stable Angina Pectoris Symptoms of angina with a consistent amount of physical exertion that is relieved with rest that has been present for a long duration. Unstable Angina Pectoris Three different presentations of unstable angina exist. [healio.com]

Mortality rate is about 7.5% when systolic hypertension is present, 8.4% when the ECG is abnormal, and 12% when both are present. Type 2 diabetes about doubles the mortality rate for each scenario. [merckmanuals.com]

Treatment

In these patients, treatments other than a beta blocker may be preferred. [bjcardio.co.uk]

One patient in the WL group died of an acute MI and received no acupuncture treatment. [mdedge.com]

The proportion of patients in each treatment group who had clinically significant changes in the other four Seattle Angina Questionnaire scales (The physical limitation, angina stability, treatment satisfaction, and quality of life) [ Time Frame: Day [clinicaltrials.gov]

Treatment strategies that begin with either immediate revascularization or optimal medical therapy with antianginal agents significantly improve angina frequency and quality of life. [ncbi.nlm.nih.gov]

In the INVEST Study, 17 over 22,500 patients with hypertension and CAD were randomised to a verapamil-based treatment regimen or an atenolol-based treatment regimen. [ecrjournal.com]

Prognosis

The patient’s main concern was not her angina but the effect the angina would have on her prognosis particularly as she had teenage children to bring up. [academic.oup.com]

The prognosis of stable angina varies widely depending on severity of symptoms, extent of atherosclerosis and presence of other risk factors and co-morbidities. The presence of impaired left ventricular function is associated with a poor prognosis. [wikidoc.org]

How is prognosis predicted in a patient with CAD and stable angina? Left ventricular ejection fraction is a very important variable in patients with CAD. 2 The lower it is, the higher the mortality. [patientcareonline.com]

It helps define prognosis 5 and options for revascularisation. [nps.org.au]

The increase in the prevalence of DM and its associated adverse effect on CAD progression and prognosis has created a global health burden. [dovepress.com]

Etiology

Etiology and Pathophysiology Anginal symptoms occur during times of myocardial ischemia caused by a mismatch between coronary perfusion and myocardial oxygen demand. [unboundmedicine.com]

This is a controversial topic, as no clear etiology has been seen. [healio.com]

Etiology and pathogenesis: see Ischemic Heart Disease. Clinical Features and Natural History Top 1. Symptoms : The clinical diagnosis of angina is based on history. [empendium.com]

Examples include increased catecholamine levels, as with vigorous exertion or mental-stress tachycardia of any etiology; hypertension; and left ventricular hypertrophy. [mdmag.com]

Epidemiology

This Primer by Campbell and colleagues discusses the epidemiology, mechanisms, diagnosis, prevention and treatment of ischaemic stroke. Bruce C. V. Campbell, Deidre A. De Silva, Malcolm R. Macleod, Shelagh B. Coutts, Lee H. Schwamm, Stephen M. [nature.com]

Epidemiology CAD is the leading cause of death for adults both in the United States and worldwide. CAD is responsible for about 1 in every 3 deaths in the United States alone. [unboundmedicine.com]

During the epidemiologic Dallas Heart Study, Banks and colleagues assessed 1,480 women to evaluate clinical characteristics of women with angina. [cardiovascularbusiness.com]

Epidemiology of Angina. In: Martin CR, Preedy VR, eds. The Scientific Basis of Health Care: Angina. Enfield, NH: Science Publishers; 2012:1-20. 2. Wilson PWF, Douglas PS, Alpert JS, Simons M, Breall JA. Prognosis after myocardial infarction. [medicographia.com]

Epidemiology Stable angina remains the most common manifestation of ischemic heart disease, and it is estimated that over 6 million people in the United States alone suffer from angina. [cancertherapyadvisor.com]

Pathophysiology

Pathophysiology [ edit ] Angina results when there is an imbalance between the heart's oxygen demand and supply. [en.wikipedia.org]

States of increased oxygen demand or decreased supply, as described in Pathophysiology, may cause angina. [healio.com]

Etiology and Pathophysiology Anginal symptoms occur during times of myocardial ischemia caused by a mismatch between coronary perfusion and myocardial oxygen demand. [unboundmedicine.com]

Recent advances in the management of chronic stable angina I: approach to the patient, diagnosis, pathophysiology, risk stratification, and gender disparities. Vasc Health Risk Manag. 2010 ;6: 635 – 56. Google Scholar | Crossref | Medline 15. [journals.sagepub.com]

Despite the visual appeal of this model, 1 it doesn’t accurately convey what we know about the pathophysiology of coronary artery disease. [consultqd.clevelandclinic.org]

Prevention

The NSF recommends that acute chest pain is treated initially with sublingual nitrate therapy. 2 Background (prophylactic) therapy with beta-blockers, other nitrates or calcium channel blockers is indicated in all patients to prevent recurrence of an [pharmaceutical-journal.com]

The goals of therapy are therefore to stabilize plaque and prevent progression and prevent or reduce damage from plaque rupture and thrombotic complications. [dovepress.com]

Heart Association Council for High Blood Pressure Research and the Councils on Clinical Cardiology and Epidemiology and Prevention. [wikidoc.org]

You may need to take more medicines to help prevent you from having angina. [ufhealth.org]

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