The present study suggests thus that cadmium can increase the urinary excretion of anionic macromolecules such as albumin by reducing the glomerular polyanion charge. [ncbi.nlm.nih.gov]

The purpose of the work was to permit leading investigators in the field to present a critical review with sufficient documentation to support their interpretations and conclusions. [books.google.com]

The present results will be disseminated to the general public through the Ministry of Environment in Japan. [bmjopen.bmj.com]

Cadmium is also present at alarmingly high levels in cigarette smoke. [livescience.com]

• Fatigue

  Acute inhalation of Cadmium dusts, fumes or soluble salts may produce cough, pneumonitis and fatigue. Manifestations of Cadmium toxicity may be lessened or delayed by an individualâ s protective and detoxification capacities. [chelationmedicalcenter.com]

  Overexposure may cause fatigue, headaches, nausea, vomiting, abdominal cramps, diarrhea, and fever. [rarediseases.org]

  Could cadmium be responsible for some of the neurological signs and symptoms of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. Med Hypotheses. 2012 Sep;79(3):403-7. doi: 10.1016/j.mehy.2012.06.007. Epub 2012 Jul 12. [globalhealingcenter.com]

  […] with lead-containing paint Action : heme synthesis disruption via inhibition of aminolevulinate dehydratase (catalyzes the conversion of aminolevulinic acid to porphobilinogen ) Clinical features Nervous system Polyneuropathy, encephalopathy, headache, fatigue [amboss.com]

  MFF, or "brass founder’s ague," "zinc shakes," or "Monday morning fever" as it is variously known, is characterized by fever, headache, fatigue, dyspnea, cough, and a metallic taste occurring within 3-10 hours after exposure. [emedicine.medscape.com]

• Burning Feet

  […] of the margins of the gums Teratogenicity Diagnosis Inorganic mercury in urine Organic mercury in blood Treatment References: [26] [27] [28] [29] [30] Thallium Sources of exposure Glass industry Rat poison Clinical features Hair loss Polyneuropathy (“burning [amboss.com]

• Nausea

  Nausea and Vomiting Ingestion of a large dose of cadmium can cause severe gastrointestinal effects. [livestrong.com]

  Overexposure may cause fatigue, headaches, nausea, vomiting, abdominal cramps, diarrhea, and fever. [rarediseases.org]

  Nausea, vomiting, diarrhea, and prostration usually occur within 15 minutes after ingestion and subside within 24 hours. Inhalation of cadmium fumes in industry produces an acute, extremely severe inflammation of the lungs that may be fatal. [britannica.com]

  Nausea, vomiting and diarrhoea. Impaired sensation. Difficulty breathing, cough, chest pain. Complications include pneumonitis and pulmonary oedema. [patient.info]

  Oral poisoning appear the following clinical signs of intoxication: profuse nausea and vomiting; strong, cutting and sharp pain in the abdomen; multiple diarrhea; weakness; rapid pulse; lowering blood pressure; may develop severe dehydration, shock. [medicalj-center.info]

• Abdominal Pain

  Gastrointestinal symptoms include a flu-like illness (gastroenteritis) that is characterized by vomiting; abdominal pain; fever; and diarrhea, which, in some cases, may be bloody. [rarediseases.org]

  General considerations Overview of principal metal toxicities Signs and Symptoms Diagnosis Further information Treatment Arsenic Acute Nausea and vomiting Abdominal pain QT prolongation Chronic Hyperkeratosis Mees' lines : white bands across the nails [amboss.com]

  Ingested cadmium poisoning causes symptoms of: shock vertigo choking salivation dyspepsia convulsions abdominal pain muscle cramps nausea, vomiting loss of consciousness Breathing high levels of cadmium can severely irritate and damage your lungs. [healthblurbs.com]

  Gastrointestinal upset (abdominal pain, gingivitis and stomatitis, nausea, vomiting). Renal problems include acute renal failure, nephrotic syndrome and acute tubular necrosis. [patient.info]

  Clinical signs of chronic cadmium poisoning: increased secretion of saliva (sialorrhea); nausea and vomiting; frequent abdominal pain, heartburn; headache, dizziness; cramps; General weakness, drowsiness, tendency to depression; the appearance of sections [medicalj-center.info]

• Hypertension

  Age distribution, smoking rates and history of hypertension among patients with Itai-itai disease, screened cases and controls are shown in table 1. [bmjopen.bmj.com]

  However, chronic low-level exposure may cause renal insufficiency and hypertension independent of tubulointerstitial disease. [msdmanuals.com]

  […] and, possibly, years later, cancer. cadmium poisoning A condition associated with industrial exposure; cadmium poisoning occurred in Japan due to contamination of drinking water by mining runoffs, resulting in itai-itai (“ouch-ouch”) disease, possibly hypertension [medical-dictionary.thefreedictionary.com]

  In severe toxic damage of the kidneys developing hypertension. The examination of these patients revealed renal failure. It can be acute or chronic. Treatment of this condition includes hemodialysis, drug therapy and diet. [medicalj-center.info]

  There were differences in the occurrence of diabetes and hypertension between cases and referents, and a tendency towards a difference in smoking habits. [ehjournal.biomedcentral.com]

• Ulcer

  The most common direct causes of death in these patients were bronchopneumonia/pneumonia (10 deaths, 37% of the patients) and GI tract diseases (nine deaths, 33% of the patients) including haemorrhage and ulcers (see online supplementary tabl e 2 ). [bmjopen.bmj.com]

  […] in children Cadmium Irritation of the airways Kidney damage Lung disease Acute toxicity: cadmium in blood Chronic toxicity: cadmium and β2‑microglobulin in urine Chronic exposure causes Itai‑itai disease No known antidote Chromium Contact dermatitis Ulcerations [amboss.com]

• Bone Pain

  Itai-Itai disease, resulting from cadmium poisoning, includes a number of health effects including the weakening and deformation of bones, gait abnormalities, bone pain, anemia, coughing, kidney failure and death. [worstpolluted.org]

  pain and is associated with renal tubular dysfunction. 1–3 Itai-itai disease mainly affects women residing in rice farming areas irrigated by the contaminated Jinzu River in Toyama, Japan. 1–3 As of 28 December 1999, 410 patients were officially diagnosed [bmjopen.bmj.com]

• Back Pain

  pain, cancer, and peripheral neuropathy. [chelationmedicalcenter.com]

  Toxic metal accumulation in the kidneys including aluminum, mercury and cadmium, also contributes to kidney infections, kidney stones, electrolyte imbalances, back pain, and edema. [tvernonlac.com]

• Arthralgia

  Later on you may experience some of these toxic cadmium inhalation symptoms: dyspnea sweating shivering coughing arthralgia wheezing dry throat headache chest pain pneumonitis muscle weakness Inhalation of cadmium fumes can cause severe lung inflammation [healthblurbs.com]

• Suggestibility

  The present study suggests thus that cadmium can increase the urinary excretion of anionic macromolecules such as albumin by reducing the glomerular polyanion charge. [ncbi.nlm.nih.gov]

  There is little evidence to suggest a physiologic role for the metal. [books.google.com]

  These data suggested that the causes of death in the many patients with Itai-itai disease before our study may be Cd poisoning or neuralgia. [bmjopen.bmj.com]

  Useful For Suggests clinical disorders or settings where the test may be helpful Detecting exposure to cadmium, a toxic heavy metal Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory [mayomedicallaboratories.com]

  Other studies have suggested that, over the timeframe of 1980 - 1985, levels of cadmium intake have been relatively constant ( OECD 1994 ). [cadmium.org]

• Renal Insufficiency

  However, chronic low-level exposure may cause renal insufficiency and hypertension independent of tubulointerstitial disease. [msdmanuals.com]

  View Article Google Scholar Lin JL, Tan DT, Hsu KH, Yu CC: Environmental lead exposure and progressive renal insufficiency. Arch Intern Med. 2001, 161: 264-271. 10.1001/archinte.161.2.264. [ehjournal.biomedcentral.com]

• Neuralgia

  These data suggested that the causes of death in the many patients with Itai-itai disease before our study may be Cd poisoning or neuralgia. [bmjopen.bmj.com]

• Glycosuria

  The effects of cadmium proximal renal function are characterized by increased cadmium in the urine, proteinuria (primarily Beta-2-microglobulin), aminoaciduria, glycosuria, and decreased renal tubular reabsorption of phosphate. [pathopedia-india.com]

The treatment is performed in hospital at the Department of toxicology or intensive care. There is no specific antidote. Even with timely treatment the patient can later develop severe kidney disease, requiring long-term or permanent cure. [medicalj-center.info]

Information about a therapy, service, product or treatment does not in any way endorse or support such therapy, service, product or treatment and is not intended to replace advice from your doctor or other registered health professional. [betterhealth.vic.gov.au]

Treatment with chelation therapy can stabilize renal function, but recovery may be incomplete. Cadmium exposure due to contaminated water, food, or tobacco and, mainly, due to workplace exposures can cause nephropathy. [msdmanuals.com]

No effective treatment for cadmium toxicity exists. For the general public, the primary source of exposure to cadmium is dietary. Smoking tobacco adds an additional burden of cadmium. [atsdr.cdc.gov]

General considerations Overview of principal metal toxicities Signs and Symptoms Diagnosis Further information Treatment Arsenic Acute Nausea and vomiting Abdominal pain QT prolongation Chronic Hyperkeratosis Mees' lines : white bands across the nails [amboss.com]

These immunological alterations of CKD may be observed in patients with Itai-itai disease, causing infections such as pneumonia and GI inflammation and contributing to a poor prognosis. [bmjopen.bmj.com]

Epidemiology Heavy metal poisoning is rare in the UK, even in industries where there is an increased risk. [ 1 ] The most common cause of heavy metal poisoning is lead. [patient.info]

Most of the available epidemiological information on cadmium has been obtained from occupationally exposed workers or on Japanese populations in highly contaminated areas. [cadmium.org]

[…] out, H yperuricemia/ H ypertension References: [7] [8] [9] [10] [11] [12] [13] [14] [15] [16] [17] [18] [19] [20] [21] Cadmium Iron Definition : chemical element often used as supplement in pediatrics and prenatal care and in the management of anemia Epidemiology [amboss.com]

Studies and regulatory actions involving cadmium exploded after this incident, and research performed in the United States in the 1960s confirmed the carcinogenic effects of the metal through rodent and epidemiological studies. [dartmouth.edu]

Useful For Suggests clinical disorders or settings where the test may be helpful Detecting exposure to cadmium, a toxic heavy metal Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory [mayomedicallaboratories.com]

[…] and urine Welder's lung None References: [1] [2] [3] [4] [5] Arsenic Sources of exposure Metal smelting ;, pesticides, herbicides, contaminated water (esp. in developing countries), ore mining, semiconductor production, paint and glass manufacturing Pathophysiology [amboss.com]

The Centers for Disease Control and Prevention is authorized by IACET to offer .15 IACET CEU's for this program. [atsdr.cdc.gov]

"In mice, chronic cadmium exposure has been shown to cause liver failure, but we need to understand more about the factors that may cause liver disease in humans, and whether we can do anything to prevent it." [sciencedaily.com]

Basophilic stippling of erythrocytes on peripheral blood smear Microcytic, hypochromic anemia Imaging (not routinely indicated): lead flecks on abdominal x-ray, lead lines on long-bone x-rays Inspection of the patient's environment for lead sources to prevent [amboss.com]

Extensive preventative hygiene programs and medical follow-up programs have been developed to control the risk related to cadmium exposure at the workplace (ACGIH 1996, OSHA 1992, Lauwerys 1986, Cadmium Council 1986). [cadmium.org]

View Article Google Scholar Hwang SJ, Tsai JC, Chen HC: Epidemiology, impact and preventive care of chronic kidney disease in Taiwan. Nephrology (Carlton). 2010, 15 (Suppl 2): 3-9. [ehjournal.biomedcentral.com]