Presentation
Case Presentation A previously healthy 14-year-old girl presents to the emergency department with 3 days of worsening left-sided abdominal pain. She reports multiple episodes of nonbloody, nonbilious emesis and constipation. [pedsinreview.aappublications.org]
A brief summary of lubiprostone and linaclotide is also presented. The quality of evidence is presented by adopting the Grading of Recommendations, Assessment, Development and Evaluation system. [ncbi.nlm.nih.gov]
This study presented interesting findings that support the association between constipation and methanogenic bacteria. [frontiersin.org]
[…] in the stool, there is a history of inflammatory bowel disease or colon cancer in a person's family, or it is of new onset in someone who is older. [11] Treatment of constipation depends on the underlying cause and the duration that it has been present [en.wikipedia.org]
Gastrointestinal
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Abdominal Pain
Other common side effects of LINZESS include gas, stomach-area (abdominal) pain, swelling, or a feeling of fullness or pressure in your abdomen (distension). [linzess.com]
Case Presentation A previously healthy 14-year-old girl presents to the emergency department with 3 days of worsening left-sided abdominal pain. She reports multiple episodes of nonbloody, nonbilious emesis and constipation. [pedsinreview.aappublications.org]
The fresh bark, however, causes nausea, vomiting and griping abdominal pain. [ncbi.nlm.nih.gov]
There is no statistically significant difference in efficacy between MgO and Lcr35, but less abdominal pain occurred when using Lcr35. [frontiersin.org]
Specialty Gastroenterology Symptoms Infrequent or hard to pass bowel movements, abdominal pain, bloating [3] [2] Complications Hemorrhoids, anal fissure, fecal impaction [4] Causes Slow movement of stool within the colon, irritable bowel syndrome, celiac [en.wikipedia.org]
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Early Satiety
Borody et al. ( 42 ) performed FMT on 4 patients with chronic constipation and demonstrated immediate improvements in symptoms, such as abdominal pain, early satiety, and nausea, as well as a significant improvement in defecation frequency to once or [frontiersin.org]
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Black Stools
Call your doctor or go to the nearest hospital emergency room right away if you develop unusual or severe stomach-area (abdominal) pain, especially if you also have bright red, bloody stools or black stools that look like tar. [linzess.com]
Workup
Microbiology
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Staphylococcus Aureus
aureus and fungi ( 5 ). [frontiersin.org]
Rhythm
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Torsades De Pointes
Prucalopride The cardiovascular toxicity of cisapride and tegaserod is related to their nonspecific effect on the delay rectifying potassium (HERG-K) channel that leads to prolong QT interval, precipitating torsade de pointes. [ncbi.nlm.nih.gov]
Treatment
More than 70% of respondents noted that having to take just one pill a day made Resotran an easy treatment to follow. [badgut.org]
[…] as the initial conservative treatment for chronic constipation. [ncbi.nlm.nih.gov]
How long does treatment need to continue? Length of treatment varies from child to child. In general, we must treat younger children for longer periods of time than older children. [med.virginia.edu]
Diarrhea often begins within the first 2 weeks of LINZESS treatment. Stop taking LINZESS and call your doctor right away if you get severe diarrhea during treatment with LINZESS. [linzess.com]
[…] from 2.0 0.3 at pretreatment to 3.3 0.2 at 12 weeks post-treatment ( p 0.0025). [frontiersin.org]
Prognosis
Furthermore, it has a very variable rate of success and is very case dependent. [29] Prognosis Complications that can arise from constipation include hemorrhoids, anal fissures, rectal prolapse, and fecal impaction. [15] [22] [46] [47] Straining to pass [en.wikipedia.org]
Etiology
Constipation: etiology, evaluation and management. New York: Springer. a b c Tabbers, M.M.; DiLorenzo, C.; Berger, M.Y.; Faure, C.; Langendam, M.W.; Nurko, S.; Staiano, A.; Vandenplas, Y.; Benninga, M.A. (2014). [en.wikipedia.org]
Epidemiology
Epidemiology Constipation is the most common chronic gastrointestinal disorder in adults. [en.wikipedia.org]
Epidemiology of constipation in North America: A systematic review. Am J Gastroenterol. 2004; 99 :750–9. [ PubMed ] [ Google Scholar ] 2. Wald A, Scarpignato C, Mueller-Lissner S, et al. [ncbi.nlm.nih.gov]
Pathophysiology
"Constipation of anorectal outlet obstruction: Pathophysiology, evaluation and management". Journal of Gastroenterology and Hepatology. 21 (4): 638–646. doi : 10.1111/j.1440-1746.2006.04333.x. [en.wikipedia.org]
Prevention
Constipation is usually easier to prevent than to treat. [en.wikipedia.org]
Constipation prevention: Empiric use of stool softeners questioned. Geriatrics. 1991; 46 :84–6. [ PubMed ] [ Google Scholar ] 29. McRorie JW, Daggy BP, Morel JG, Diersing PS, Miner PB, Robinson M. [ncbi.nlm.nih.gov]