Usually, these patients will present with portal hypertension signs and symptoms, including splenomegaly, gastroesophageal varices, hematemesis, and ascites. Hepatic function is commonly preserved until late stages 2. [radiopaedia.org]

Periportal fibrotic bands and widened fissures Capsular calcification (parallel or perpendicular to liver surface) • Portal hypertension in advanced disease Splenomegaly and varices • US: Bull’s-eye lesion: Represents anechoic portal vein surrounded by [radiologykey.com]

Imaging studies may reveal enlargement of the left liver lobe without changes in the liver parenchyma or splenomegaly. [onlinelibrary.wiley.com]

The chronic consequences of Schistosoma mansonii infection include portal hypertension with splenomegaly, esophageal varices, and ascites. [coursera.org]

On examination there was massive splenomegaly with minimal ascites. Magnetic resonance imaging revealed minimally shrunken liver with nodular regenerative hyperplasia. All autoimmune and viral markers were negative. [tropicalgastro.com]

The relative risk to develop hepatosplenomegaly in persons infected with S. mansoni have been reported in correlation with HLA-A1 and B5[ 15 ]. [wjgnet.com]

Hepatosplenomegaly and lymphadenopathy are usual. Chronic Schistosomiasis may present in a wide variety of forms: Urinary schistosomiasis usually caused by S. haematobium – painful urination (dysuria), and blood in urine (hematuria). [web.stanford.edu]

Portal hypertension can develop and cause hepatosplenomegaly, ascites, and esophageal varices. [meddean.luc.edu]

[…] nervous system. schistosomiasis manso ni infection with Schistosoma mansoni, living chiefly in the mesenteric veins but migrating to deposit eggs in venules, primarily of the large intestine; eggs lodging in the liver may lead to peripheral fibrosis, hepatosplenomegaly [medical-dictionary.thefreedictionary.com]

A syndrome consisting of some combination of cough, fever, malaise, hyper-eosinophilia, lymphadenopathy, and hepatosplenomegaly appear anywhere between 2 to 12 weeks following exposure to infectious cercariae.This syndrome is known as Katayama fever [infectionlandscapes.org]

Portal-systemic shunting rather than liver dysfunction is the main cause of PSE in chronic hepatic schistosomiasis japonicum (HSJ) patients. [ncbi.nlm.nih.gov]

In early phases of infection, a predominantly hypercellular nonfibrotic granuloma response produces liver dysfunction that is not clinically detectable. [onlinelibrary.wiley.com]

In HSJ patients with PSE, the extrapyramidal symptoms and MRI findings were similar to those seen in welders [ 19 ]. [journals.plos.org]

Deficits in attention (n 9, 21.9%), disturbance of sleep (n 7, 17%), logopathy (n 3, 7.3%), rigidity (n 9, 21.9%), tremor (n 6, 14.6%), and bradykinesia (n 8, 19.5%) were observed in overt PSE. [journals.plos.org]

varices Pulmonary Venous Hypertension Schistosome eggs can be lodged in the lungs Dyspnea, cough, fatigue, swelling of lower extremities, pulmonary edema Can lead to cardiac failure No cure, only 50% patients clinically responsive to treatment Untreated [quizlet.com]

varices – essentially, varicose veins in the esophagus and stomach, one of the most serious complications because they can rupture and bleed. [liversupport.com]

The management of patients with esophageal and gastric varices remains challenging, particularly when prophylactic procedures are considered 82. [elsevier.es]

Glx is a product of ammonia metabolism; increase of Glx is a major cause of brain edema in hepatic encephalopathy [ 21 ]. [journals.plos.org]

Transforming growth factor-alpha and epidermal growth factor receptor in chronic liver disease and hepatocellular carcinoma. Liver 1999;19: 318-325. 39- Oliveira SDS, Silva RC, Silva CLM. [pacificejournals.com]

carcinoma, particularly secondary to the S.Mansoni subtype Promoted articles (advertising) [radiopaedia.org]

Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level. Jama 2006;295:65–73. CrossRef PubMed Google Scholar 23. Erhardt A, Göbel T, Ludwig A, et al. [link.springer.com]

carcinoma liver failure – scar tissue can impair the functioning of normal liver tissuebleeding from blood vessels in the oesophagus or upper stomach (oesophageal varices) increased blood pressure in veins that take blood to the liver (portal hypertension [betterhealth.vic.gov.au]

carcinoma) and (hepatoma) – risk varies with the cause of liver disease Enlarged spleen (Splenomegaly) Esophageal and gastric varices – essentially, varicose veins in the esophagus and stomach, one of the most serious complications because they can rupture [liversupport.com]