[…] with or without lymphadenopathy Stage III : characterized by absolute lymphocytosis and anemia (hemoglobin Stage IV : characterized by absolute lymphocytosis and thrombocytopenia ( 3 ) with or without lymphadenopathy, hepatomegaly, splenomegaly, or anemia [en.wikipedia.org]

[…] myeloid leukemia USMLE Step 2 style questions 2 questions Chronic lymphoid leukemia USMLE Step 1 style questions 2 questions Chronic lymphoid leukemia USMLE Step 2 style questions 2 questions Preview A 71-year-old man comes to the clinic because of fatigue [osmosis.org]

Imatinib: Chronic fatigue (mostly correlated with musculoskeletal pain and muscular cramps) is a major factor reducing quality of life. 47 Hypophosphatemia and decrease in bone mineral density has been noted in a small group of patients, suggesting that [jnccn.org]

lymphadenopathy Stage III : characterized by absolute lymphocytosis and anemia (hemoglobin Stage IV : characterized by absolute lymphocytosis and thrombocytopenia ( 3 ) with or without lymphadenopathy, hepatomegaly, splenomegaly, or anemia Binet classification [en.wikipedia.org]

12 months, clinical judgement should be used, considering problems with adherence (which can be common given drug toxicity at start of therapy), rate of decline in BCR-ABL1 (the faster, the better), and how far from the 10% cutoff the BCR-ABL1 value falls [jnccn.org]

Chronic lymphocytic leukemia Other names B-cell chronic lymphocytic leukemia (B-CLL) [1] Peripheral blood smear showing CLL cells Specialty Hematology and oncology Symptoms Early : None [2] Later : Non-painful lymph nodes swelling, feeling tired, fever, weight [en.wikipedia.org]

"Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015". [en.wikipedia.org]

Ponatinib labeling contains a black box warning regarding vascular occlusion, heart failure, and hepatotoxicity. [jnccn.org]

Resumption of TKI therapy immediately after recurrence results in the achievement of undetectable disease in almost all patients. 149 – 160 TKI withdrawal syndrome (aggravation or new development of musculoskeletal pain and/or pruritus after discontinuation [jnccn.org]