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Chronic Pelvic Pain Syndrome


Presentation

  • EVIDENCE SYNTHESIS: Twenty-eight RCTs identified were eligible for this review and presented.[ncbi.nlm.nih.gov]
  • Patients' clinical presentation and physical exam findings are reviewed. All men were clinically phenotyped with the UPOINT system. Pelvic floor spasm and not infection was prominent in these men.[ncbi.nlm.nih.gov]
  • Options for first-line treatment include antibiotics, α-adrenergic antagonists (if voiding LUTS are present) and simple analgesics.[ncbi.nlm.nih.gov]
  • Abstract Chronic pelvic pain syndrome (CPPS) presents with a variety of symptoms affecting multiple systems. There is no universal treatment that can be given to all patients with CPPS.[ncbi.nlm.nih.gov]
  • The patient presented for acupuncture treatment, complaining of constant pain in the perineal region, varying in severity from 5 to 9 on a 0 to 10 pain scale.[ncbi.nlm.nih.gov]

Treatment

  • CONCLUSION: However the treatment of CP-CPPS is challenging and difficult for the urologists. This clinical study showed that the acupuncture treatment is a safe and effective treatment of category IIIB CP-CPPS. Copyright 2015 Elsevier Inc.[ncbi.nlm.nih.gov]
  • After three treatments with acupuncture, the pain was reduced to 3.5; after a further three treatments the pain was reduced to 2.5; and after 10 months, the pain was reduced to either 2 or 3 and has remained stable for two years since then.[ncbi.nlm.nih.gov]
  • The protocol required an initial 6-day clinic for training followed by a 6-month self-treatment period.[ncbi.nlm.nih.gov]
  • Treatment was applied twice a week every third day for 4 weeks.[ncbi.nlm.nih.gov]
  • NIH-CPSI was completed by each patient before and 6, 8, 16, 24 weeks after the treatment. Mean values of total CPSI score and subscores after the treatment and on follow-up following the treatment were compared.[ncbi.nlm.nih.gov]

Etiology

  • PURPOSE: Although chronic prostatitis/chronic pelvic pain syndrome is a prevalent urological disorder among men of all ages, its etiology remains unknown.[ncbi.nlm.nih.gov]
  • PURPOSE: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a prevalent urologic disorder among men, but its etiology is still poorly understood.[ncbi.nlm.nih.gov]
  • BACKGROUND: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a common problem with unclear etiology.[ncbi.nlm.nih.gov]
  • INTRODUCTION: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a common etiology of premature ejaculation (PE). However, the current data are insufficient to explain this relationship and to support routine screening of men with PE.[ncbi.nlm.nih.gov]
  • INTRODUCTION: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a common debilitating condition of unclear etiology. Sexual dysfunction is an important component of the clinical phenotype of CP/CPPS.[ncbi.nlm.nih.gov]

Epidemiology

  • KEYWORDS: cystitis; epidemiologic research design; interstitial; pain; prostate; symptom assessment[ncbi.nlm.nih.gov]
  • Epidemiological and neuroimaging data were collected from participants with UCPPS (n 52), IBS (n 39), and healthy sex- and age-matched controls (n 61).[ncbi.nlm.nih.gov]
  • […] cystitis/bladder pain syndrome and chronic prostatitis/chronic pelvic pain syndrome as 'flares', and to investigate their associated healthcare utilization and bother at two sites of the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Epidemiology[ncbi.nlm.nih.gov]
  • University, Feinberg School of Medicine, Chicago, IL, USA fNeuroscience Graduate Program, University of Southern California, Los Angeles, CA, USA gFunctional MRI Laboratory, University of Michigan, Ann Arbor, MI, USA hDepartment of Biostatistics and Epidemiology[ncbi.nlm.nih.gov]
  • States of America. 8 Department of Neurology, Stanford University, Palo Alto, California, United States of America. 9 Department of Anesthesiology, University of Alabama, Birmingham, Alabama, United States of America. 10 Department of Biostatistics and Epidemiology[ncbi.nlm.nih.gov]
Sex distribution
Age distribution

Pathophysiology

  • With its multifactorial pathophysiology and its various clinical presentations, the management of CP/CPPS demands a phenotypic-directed approach addressing the individual clinical profile of each patient.[ncbi.nlm.nih.gov]
  • Abstract Psychological factors may play a role in the pathophysiology of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS).[ncbi.nlm.nih.gov]
  • OBJECTIVE: To examine a series of candidate markers for urological chronic pelvic pain syndrome (UCPPS), selected based on their proposed involvement in underlying biological processes so as to provide new insights into pathophysiology and suggest targets[ncbi.nlm.nih.gov]
  • Similarly, patients randomized to acupuncture reported a reduction in other white blood cell parameters examined, supporting the possibility that immunity might be important in the pathophysiology of CP/CPPS.[ncbi.nlm.nih.gov]
  • Studying biological factors that predict trends in symptom change in chronic pain may uncover novel pathophysiological mechanisms and potential therapeutic targets.[ncbi.nlm.nih.gov]

Prevention

  • ., diarrhea), symptom intensity (mild to severe), duration (minutes to years), and frequency (daily to CONCLUSIONS: Given their negative impact, future research should focus on approaches to prevent flares, and to reduce their frequency, severity, and[ncbi.nlm.nih.gov]
  • Our findings also show the characteristics of flares most bothersome to patients (i.e. increased pelvic pain and duration), and thus of greatest importance to consider in future research on flare prevention and treatment. 2014 The Authors.[ncbi.nlm.nih.gov]

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