The third patient initially had L3 inferior partial collapse and 1 year later T8 involvement with multifocal disease. Follow-up was available over 3 years. [ncbi.nlm.nih.gov]

When this condition affects the spine it needs to be checked carefully to ensure the spine does not collapse. Opening Hours Monday - Friday: 9.00am - 4.30pm [queenslandrs.com.au]

Because of its recurrent febrile episodic course, Majeed syndrome should also be included in the differential diagnosis of the periodic fever syndromes. [ncbi.nlm.nih.gov]

Chronic granulomatous disease (CGD) is a primary immunodeficiency that leads to severe recurrent infection and inflammatory complications that are usually difficult to diagnose and treat. [ncbi.nlm.nih.gov]

CONCLUSIONS: Parotid mass or swelling is a common presentation of CRMO involving the mandible. The possibility of this diagnosis should be raised when typical clinical and imaging features are present. [ncbi.nlm.nih.gov]

Parotid swelling and chronic recurrent multifocal osteomyelitis of mandible in children – “Parotid mass or swelling is a common presentation of CRMO involving the mandible.” [saidsupport.org]

OBJECTIVE: Chronic recurrent multifocal osteomyelitis/ chronic non-bacterial osteomyelitis (CRMO/ CNO) is a rare auto-inflammatory disease and typically manifests in terms of musculoskeletal pain. [ncbi.nlm.nih.gov]

Risk factors for development of non-specific musculoskeletal pain in preteens and early adolescents: a prospective 1-year follow-up study. [doi.org]

A case of acute lymphotic leukemia which was difficult to make a diagnosis of CRMO for moving arthralgia and periarticular swelling. [saidsupport.org]

A 13-year-old male presented with a three-year history of recurrent discharging right thigh sinus and an 11-day history of a left shoulder swelling with discharging sinus. [ncbi.nlm.nih.gov]

Six months later, this child presented with right shoulder pain and the subsequent imaging demonstrated bilateral clavicular lesions. [ncbi.nlm.nih.gov]

A 17-year-old man presented with debilitating dorsal spine pain. Magnetic resonance imaging of the spine revealed bone lesions at multiple vertebral levels. After failure of antibiotic treatment, the diagnosis of CRMO was suggested. [ncbi.nlm.nih.gov]

Two genetic syndromes have CRMO as a prominent phenotype-Majeed syndrome and deficiency of the interleukin-1 receptor antagonist-and suggest that interleukin-1 may be a key cytokine in disease pathogenesis. [ncbi.nlm.nih.gov]

It is characterized by insidious onset of pain, local bone expansion and radiological findings suggestive of osteomyelitis at multiple sites. CRMO predominantly affects metaphyses of long bones but clavicle and mandible are suggestive of diagnosis. [moh-it.pure.elsevier.com]

Both cases were initially confused with other entities, leading to unnecessary initial treatments and a delayed diagnosis. [ncbi.nlm.nih.gov]

Maksymowych WP (2003) Bisphosphonates for arthritis–a confusing rationale. J Rheumatol 30(3):430–434 PubMed Google Scholar 28. [doi.org]

[…] demonstrated in primary and secondary chronic osteomyelitis, with extensive sclerosis, variable osteolysis and periosteal reaction on diagnostic imaging Osteochemonecrosis of the Jaws Osteoradionecrosis Cemento osseous dyplasia (COD) Has often been confused [pathologyoutlines.com]

Peripheral blood films showed hypochromia and microcytosis. The sites involved by CRMO were periarticular, mainly around the elbow, knee, wrist and small joints of the hand. [ncbi.nlm.nih.gov]