Presentation
The list of potential etiologies in these patients can be long, particularly if presenting symptoms do not fall into recognized patterns. [pediatrics.aappublications.org]
Various autoantibodies may be present against thyroid peroxidase, thyroglobulin and TSH receptors, although a small percentage of people may have none of these antibodies present. [en.wikipedia.org]
The discussion in the previous paragraph considered all cases of nodular Hashimoto thyroiditis in the present study. [ajronline.org]
Treatment with thyroid hormone may be used when a goitre is present or the body’s natural thyroid hormone production is decreased or TSH level increased. This treatment is called replacement therapy. [labtestsonline.org.au]
The doctor may also request blood tests to ensure that no other autoimmune condition is present or developing. How is Hashimoto’s disease treated? Treatment is carried out as an outpatient and depends on how well the thyroid gland is working. [yourhormones.info]
Entire Body System
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Weight Gain
gain Small or shrunken thyroid gland (late in the disease) Treatment If you have findings of an underactive thyroid, you may receive thyroid replacement medicine. [account.allinahealth.org]
Symptoms are those of hypothyroidism, such as weight gain, increased sensitivity to cold, and fatigue; in addition, the thyroid is markedly enlarged, in many cases causing a visible goitre, which is firm and rubbery but is not usually tender. [labtestsonline.org.au]
The most common symptoms include the following: fatigue, weight gain, pale or puffy face, feeling cold, joint and muscle pain, constipation, dry and thinning hair, heavy menstrual flow or irregular periods, depression, panic disorder, a slowed heart rate [en.wikipedia.org]
Patients may also present with weight gain, myxedema, fatigue, and mental slowness as a result of hypothyroidism [ 17 ]. [ajronline.org]
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Goiter
Not everyone with thyroiditis or goiter has low levels of thyroid hormone. You may just need regular follow-up by a health care provider. [account.allinahealth.org]
Other names Chronic lymphocytic thyroiditis, autoimmune thyroiditis, struma lymphomatosa, Hashimoto's disease The thyroid of someone with Hashimoto's thyroiditis as seen with a microscope at low magnification Specialty Endocrinology Symptoms Painless goiter [en.wikipedia.org]
[…] patient with Hashimoto's thyroiditis - a case report. ( 30621642 ) Cyranska-Chyrek E...Ruchala M 2019 37 Spontaneous intracranial hypotension in Hashimoto's thyroiditis: A case report. ( 31045829 ) Liang H...Hu S 2019 38 Hashimoto's thyroiditis, nodular goiter [malacards.org]
Incidence and clinical characteristics of thyroid carcinoma after iodine prophylaxis in an endemic goiter country. Thyroid (1997) 7(5):733–41. doi:10.1089/thy.1997.7.733 CrossRef Full Text Google Scholar 58. [frontiersin.org]
Hashimoto thyroiditis can present clinically as painless firm diffuse goiter often accompanied by hypothyroidism and autoantibodies [ 1 ]. [ajronline.org]
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Fatigue
Symptoms Symptoms of Hashimoto disease may include any of the following: Constipation Difficulty concentrating or thinking Dry skin Enlarged neck or presence of goiter, which may be the only early symptom Fatigue Hair loss Heavy or irregular periods Intolerance [account.allinahealth.org]
Symptoms are those of hypothyroidism, such as weight gain, increased sensitivity to cold, and fatigue; in addition, the thyroid is markedly enlarged, in many cases causing a visible goitre, which is firm and rubbery but is not usually tender. [labtestsonline.org.au]
The most common symptoms include the following: fatigue, weight gain, pale or puffy face, feeling cold, joint and muscle pain, constipation, dry and thinning hair, heavy menstrual flow or irregular periods, depression, panic disorder, a slowed heart rate [en.wikipedia.org]
Patients may also present with weight gain, myxedema, fatigue, and mental slowness as a result of hypothyroidism [ 17 ]. [ajronline.org]
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Falling
The list of potential etiologies in these patients can be long, particularly if presenting symptoms do not fall into recognized patterns. [pediatrics.aappublications.org]
Nevertheless, antibody-dependent cell-mediated cytotoxicity is a substantial factor behind the apoptotic fall-out of Hashimoto's thyroiditis. [en.wikipedia.org]
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Myxedema
On gross examination, there is often presentation of a hard goiter that is not painful to the touch; [21] other symptoms seen with hypothyroidism, such as periorbital myxedema, depend on the current state of progression of the response, especially given [en.wikipedia.org]
Patients may also present with weight gain, myxedema, fatigue, and mental slowness as a result of hypothyroidism [ 17 ]. [ajronline.org]
Gastrointestinal
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Constipation
Symptoms Symptoms of Hashimoto disease may include any of the following: Constipation Difficulty concentrating or thinking Dry skin Enlarged neck or presence of goiter, which may be the only early symptom Fatigue Hair loss Heavy or irregular periods Intolerance [account.allinahealth.org]
Bowel movements slow down causing constipation. There may be drying of the skin and hair, and hair changes (such as thinning or loss of hair). [yourhormones.info]
[…] thyroiditis, autoimmune thyroiditis, struma lymphomatosa, Hashimoto's disease The thyroid of someone with Hashimoto's thyroiditis as seen with a microscope at low magnification Specialty Endocrinology Symptoms Painless goiter, weight gain, feeling tired, constipation [en.wikipedia.org]
Cardiovascular
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Hypotension
[…] with challenging cytological features. ( 30659000 ) Fulciniti F...Giovanella L 2019 36 Severe unilateral orbitopathy in a patient with Hashimoto's thyroiditis - a case report. ( 30621642 ) Cyranska-Chyrek E...Ruchala M 2019 37 Spontaneous intracranial hypotension [malacards.org]
Skin
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Dry Skin
Symptoms Symptoms of Hashimoto disease may include any of the following: Constipation Difficulty concentrating or thinking Dry skin Enlarged neck or presence of goiter, which may be the only early symptom Fatigue Hair loss Heavy or irregular periods Intolerance [account.allinahealth.org]
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Alopecia
] Having other autoimmune diseases is a risk factor to develop Hashimoto’s thyroiditis, and the opposite is also true. [1] Autoimmune diseases most commonly associated to Hashimoto’s thyroiditis include celiac disease, type 1 diabetes, vitiligo, and alopecia [en.wikipedia.org]
Psychiatrical
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Psychiatric Symptoms
The medical evaluation of adolescents who present with psychiatric symptoms requires a full clinical assessment to exclude organic disease. [pediatrics.aappublications.org]
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Visual Hallucination
Her visual hallucinations comprised seeing animals and unknown people on walls often engaged in violent acts and she began hearing commanding and denigrating voices. Her symptoms caused significant distress associated with decreased mood and energy. [pediatrics.aappublications.org]
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Auditory Hallucination
CASE REPORT The patient is a 14-year-old girl with no significant past medical history who described visual and auditory hallucinations beginning at age 9. [pediatrics.aappublications.org]
Neurologic
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Encephalopathy
Steroid responsive encephalopathy associated with Hashimoto’s thyroiditis (SREHT) is a more accurate description of the previously named “Hashimoto’s encephalopathy.” [pediatrics.aappublications.org]
[…] role in development of autoimmune overt hypothyroidism in premenopausal women, and the number of previous pregnancies should be taken into account when evaluating the risk of hypothyroidism in a young women [ sic ]." [38] See also [ edit ] Hashimoto's encephalopathy [en.wikipedia.org]
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Difficulty Concentrating
Symptoms Symptoms of Hashimoto disease may include any of the following: Constipation Difficulty concentrating or thinking Dry skin Enlarged neck or presence of goiter, which may be the only early symptom Fatigue Hair loss Heavy or irregular periods Intolerance [account.allinahealth.org]
Workup
We should therefore consider wider indications for a workup when this patient group presents suspect symptoms of cancer. [frontiersin.org]
"Hashimoto Thyroiditis Workup: Approach Considerations, Serum TSH Test and Other Studies, Ultrasonography". emedicine.medscape.com. Retrieved 4 December 2017. "Prasad's syndrome" (PDF). Archived from the original on 9 June 2011. [en.wikipedia.org]
HLA Type
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HLA-DR5
i.e. transmits an inhibitory signal to T cells, so reduced functioning is associated with increased T-lymphocyte activity. [16] [17] A family history of thyroid disorders is common, with the HLA-DR5 gene most strongly implicated conferring a relative [en.wikipedia.org]
Treatment
The patient had significant clinical improvement and showed resolution on neuroimaging after corticosteroid treatment. [pediatrics.aappublications.org]
Being aware of risk factors may allow earlier diagnosis and treatment. [account.allinahealth.org]
No treatment is needed in these cases. Treatment with thyroid hormone may be used when a goitre is present or the body’s natural thyroid hormone production is decreased or TSH level increased. This treatment is called replacement therapy. [labtestsonline.org.au]
Treatment is carried out as an outpatient and depends on how well the thyroid gland is working. An overactive gland usually settles down by itself and hypothyroidism develops with time. [yourhormones.info]
In most cases, the treatment needs to be taken for the rest of the person's life. [en.wikipedia.org]
Prognosis
Outlook (Prognosis) The disease stays stable for years. If it does slowly progress to thyroid hormone deficiency (hypothyroidism), it can be treated with hormone replacement therapy. [account.allinahealth.org]
PTC and FTC are well-differentiated TCs and generally have a favorable prognosis ( 7 ), contrary to MTC and ATC with poor prognosis. Thyroid lymphoma (TL) is a rare TC, accounting for 1–5% of all thyroid malignancies ( 9 ). [frontiersin.org]
In the event that hypothyroidism is caused by Hashimoto's thyroiditis, it may be recommended that the TSH levels be kept under 3.0 m IU /L. [27] Prognosis [ edit ] Overt, symptomatic thyroid dysfunction is the most common complication, with about 5% of [en.wikipedia.org]
Etiology
The list of potential etiologies in these patients can be long, particularly if presenting symptoms do not fall into recognized patterns. [pediatrics.aappublications.org]
Epidemiology
Primary thyroid B cell lymphoma affects fewer than one in a thousand persons, and it is more likely to affect those with long-standing autoimmune thyroiditis. [28] Epidemiology [ edit ] This disorder is believed to be the most common cause of primary [en.wikipedia.org]
Changing patterns in the incidence and survival of thyroid cancer with follicular phenotype – papillary, follicular, and anaplastic: a morphological and epidemiological study. [frontiersin.org]
Pathophysiology
Progressive depletion of these cells as the cytotoxic immune response leads to higher degrees of primary hypothyroidism, presenting with low T3/T4 levels, and compensatory elevations of TSH. [ citation needed ] Pathophysiology [ edit ] There are multiple [en.wikipedia.org]
Prevention
Prevention There is no known way to prevent this disorder. Being aware of risk factors may allow earlier diagnosis and treatment. [account.allinahealth.org]
[…] autoimmune diseases is a risk factor to develop Hashimoto’s thyroiditis, and the opposite is also true. [1] Autoimmune diseases most commonly associated to Hashimoto’s thyroiditis include celiac disease, type 1 diabetes, vitiligo, and alopecia. [19] Preventable [en.wikipedia.org]