A 40-year-old man presented with laryngeal papillomatosis 19 years after being treated with surgery and adjuvant radiotherapy for leiomyosarcoma of the cervical esophagus. [ncbi.nlm.nih.gov]

• Easy Bruising

  bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath; or pancreatitis --severe pain in your upper stomach spreading to your back, nausea and vomiting. [cigna.com]

• Intravenous Administration

  Local cidofovir therapy for viral hemorrhagic cystitis could be an alternative to intravenous administration of cidofovir. [ncbi.nlm.nih.gov]

  Subcutaneous administration produces exposure equivalent to that following intravenous administration. [pubmed.ncbi.nlm.nih.gov]

• Intravenous Drugs

  Because of this infrequent dosing schedule, patients do not need to have a catheter surgically implanted, as is required for other intravenous drugs for cytomegalovirus. [aidsmap.com]

  The risk factor for HIV infection was intravenous drug use in five, and sexual risk relationships in three. [journals.lww.com]

• Crying

  A previously healthy, full-term, 4-month-old boy presented with progressively weakening cry, hoarseness, and increased work of breathing. [ncbi.nlm.nih.gov]

OBJECTIVE: The treatment of recurrent respiratory papillomatosis (RRP) continues to be difficult. Adjuvant pharmacological treatment is increasingly being used, and intralesional cidofovir injection remains the leading option. [ncbi.nlm.nih.gov]

PMID 21994641. ^ "Interim Clinical Guidance for the Treatment of Monkeypox". U.S. Centers for Disease Control and Prevention. 26 May 2022. ^ a b "Details" (PDF). www.gilead.com. [en.wikipedia.org]

Potent thymidine phosphorylase (TP) inhibitors with anti-angiogenic activity are required to improve the prognosis of patients with TP-positive tumors. [ncbi.nlm.nih.gov]

Our results suggest that cidofovir-treated children have a better prognosis compared to those treated surgically only; the duration of treatment until eradication of JRRP was shorter in the former. [scielo.br]

HAART improves prognosis in HIV-associated progressive multifocal leukoencephalopathy. Neurology 52 : 623–625. PubMed Google Scholar De Luca A, Fantoni M, Tartaglione T, Antinori A (1999). [link.springer.com]

Pou AM, Rimell FL, Jordan JA, Shoemaker DL, Johnson JT, Barua P, Post JC, Ehrlich GD (1995) Adult respiratory papillomatosis: human papillomavirus type and viral coinfections as predictors of prognosis. [doi.org]

HAART improves prognosis in HIV -associated progressive multifocal leukoencephalopathy [see Comments]. Neurology 1999, 52: 623–625. 7. Andrei G, Snoeck R, Vandeputte M, De Clercq E. [journals.lww.com]

In a study of the etiology and epidemiology of acute viral lower respiratory tract infections of South Korean soldiers in our institution, six cases of severe AdV pneumonia were identified. [journals.plos.org]

Human herpesvirus 6 (HHV-6) is the etiologic agent of exanthema subitum, a febrile rash illness that can occur during early childhood and that is occasionally accompanied by convulsions. [academic.oup.com]

PMID: 27037651 Epidemiology and Outcome of Ganciclovir-Resistant Cytomegalovirus Infection After Solid Organ Transplantation: A Single Transplant Center Experience in Thailand. Bruminhent J, Rotjanapan P, Watcharananan SP. Bruminhent J, et al. [pubmed.ncbi.nlm.nih.gov]

Mandal, “Adenovirus Infections in Human Immunodeficiency Virus-Positive Patients: Clinical Features and Molecular Epidemiology,” Journal of Infectious Diseases, Vol. 172, No. 3, 1995, pp. 629-637. doi:10.1093/infdis/172.3.629 [ 3 ] M. [dx.doi.org]

Clinical epidemiology group. French hospital database on HIV. AIDS 1999 ;13: 1881 – 7. Google Scholar | Crossref | Medline | ISI 11. Tantisiriwat, W, Tebas, P, Clifford, DB, Powderly, WG, Fichtenbaum, CJ. [doi.org]

CrossRef PubMed Google Scholar Tassie JM, Gasnault J, Bentata M, Deloumeaux J, Boue F, Billaud E, Costagliola D, and the Clinical Epidemiology Group from the French Hospital Database on HIV (1999). [link.springer.com]

Epidemiology of progressive multifocal leukoencephalopathy in the United States: analysis of national mortality and AIDS surveillance data [see Comments]. Neurology 1991, 41: 1733–1736. 2. Dworkin MS, Wan PC, Hanson DL, Jones JL. [journals.lww.com]

The pathophysiology of AdV pneumonia remains unclear; few studies have been performed. [journals.plos.org]

Mechanism of action Acting as an antiviral agent by preventing the replication of CMV, cidofovir targets viral DNA polymerase and prevents transcription. [web.stanford.edu]

Nausea and vomiting due to probenecid may be prevented by taking it after meals. [webmd.com]

Cell death was specific as it was also present in a human proximal tubular epithelial cell line (HK-2), but not in a human kidney fibroblast cell line, and was prevented by probenecid. An inhibitor of caspase-3 (DEVD) prevented cidofovir apoptosis. [ncbi.nlm.nih.gov]