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Cimetidine


Presentation

  • We present this case of primary perianal EMPD to highlight an alternative treatment regimen for poor surgical candidates.[ncbi.nlm.nih.gov]
  • A 39-year-old woman presented to the Emergency Department complaining of nausea and vomiting. The patient was given intravenous cimetidine for epigastric pain and subsequently developed a dystonic reaction.[ncbi.nlm.nih.gov]
  • The method presented here is simple and rapid, and the precision and sensitivity are appropriate for the determination of cimetidine in plasma in pharmacokinetic studies. Copyright (c) 2007 John Wiley & Sons, Ltd.[ncbi.nlm.nih.gov]
  • Three patients presented with septal fasciitis and panniculitis, associated with clinical and laboratory features which precluded straight-forward classification into eosinophilic fasciitis, localised scleroderma, or lupus erythematosus profundus.[ncbi.nlm.nih.gov]
  • We present the case of a young man on maintenance hemodialysis who developed frequent episodes of 'fluttering, racing heartbeats', hot flashes, profuse sweating, anxiety, dizziness, and shortness of breath.[ncbi.nlm.nih.gov]
Intravenous Administration
  • Both drugs demonstrate biexponential elimination curves from the plasma after intravenous administration and a bimodal curve after oral administration which is probably the result of enterohepatic recirculation.[ncbi.nlm.nih.gov]
  • The precipitous nature of this example may have been due to the intravenous administration of cimetidine.[livertox.nih.gov]
  • Intravenous administration of hemin preparations may be life-saving when employed early when neuronal damage is still reversible, and may help to avoid paresis or prevent its progression.[ncbi.nlm.nih.gov]
Hypoxemia
  • Cimetidine therapy used for the treatment of gastric bleeding due to tolazoline therapy in a newborn infant was temporally associated with episodes of severe hypoxemia.[ncbi.nlm.nih.gov]
  • Hypoxemia improved during continuous tolazoline infusion, but gastrointestinal bleeding occurred. After treatment with cimetidine, there was a rapid deterioration with decreased oxygen saturation and arterial PO2 values.[ncbi.nlm.nih.gov]
Candidiasis
  • Abstract The authors evaluated the clinical efficacy of a treatment with cimetidine and zinc sulphate in a patient with chronic mucocutaneous candidiasis.[ncbi.nlm.nih.gov]
Pruritic Rash
  • The patient was treated with an intravenous infusion of cimetidine with prompt resolution of a diffuse, well demarcated, erythematous, pruritic rash. The treatment was without sequelae and permitted early discharge from the emergency department.[ncbi.nlm.nih.gov]
Confusion
  • The association of mental confusion with cardiac conduction impairment in a single patient in the context of cimetidine toxicity is highly unusual.[ncbi.nlm.nih.gov]
  • However, subsequent reports indicate that elderly patients, patients with impaired renal function, and patients with liver disease appear quite susceptible to mental confusion.[ncbi.nlm.nih.gov]
  • […] treat Zollinger-Ellison syndrome; interference with the hepatic P-450 mixed-function oxidase enzyme system, which results in drug interactions with warfarin, phenytoin, theophylline and other drugs; and central nervous system effects characterized by confusion[ncbi.nlm.nih.gov]
  • […] treat Zollinger-Ellison syndrome; interference with the hepatic P-450 mixed-function oxidase enzyme system, which results in drug interactions with warfarin, pheny-toin, theophylline and other drugs; and central nervous system effects characterized by confusion[doi.org]

Workup

  • His workup included a total of 72 h of cardiac monitoring, two-dimensional echocardiogram, and thyroid function tests, all of which were essentially unremarkable.[ncbi.nlm.nih.gov]
Decreased Oxygen Saturation
  • After treatment with cimetidine, there was a rapid deterioration with decreased oxygen saturation and arterial PO2 values. Tolazoline induces a dilatation of the pulmonary vascular system by stimulating H2 receptors.[ncbi.nlm.nih.gov]
Sinus Arrest
  • This is the first reported case of sinus arrest associated with continuous-infusion cimetidine.[ncbi.nlm.nih.gov]

Treatment

  • Pentavalent antimonials have been considered as standard treatment for leishmaniasis. Many studies are performed to find an effective and safe treatment for patients with CL.[ncbi.nlm.nih.gov]
  • None of the patients have reported any adverse effects of the systemic treatment after more than 2 years of treatment.[ncbi.nlm.nih.gov]
  • In the wild type group, the cystatin C level change of patients without cimetidine treatment was significantly larger than those with cimetidine treatment (P 0.007).[ncbi.nlm.nih.gov]
  • The authors conclude that this combined immunopotentiating treatment is safe and inexpensive to treat immunodeficiency disorders.[ncbi.nlm.nih.gov]
  • There are several treatments to date; however, most cause some type of tissue damage. Because spontaneous resolution of warts can occur, the role of cimetidine in the treatment of warts remains controversial.[ncbi.nlm.nih.gov]

Prognosis

  • Abstract The present study demonstrates a possible mechanism for the improvement of gastrointestinal cancer patients' prognosis by the histamine receptor type 2 (H2R) antagonist cimetidine.[ncbi.nlm.nih.gov]
  • For instance, in a Japanese study in 2006, colorectal cancer patients who received cimetidine following surgical removal of recurrent cancer had an improved prognosis compared to those treated with surgery only. 4 A groundbreaking study reported in the[lifeextension.com]
  • The presence of tumour infiltrating lymphocytes (TIL) within rectal tumour tissues is considered to be an independent pathological marker of good prognosis ( Harrison et al, 1994 ).[nature.com]
  • Prognosis and outcomes of patients with community-acquired pneumonia: a meta-analysis. JAMA. 1996; 275:134-41. HID. Trissel LA. Handbook on injectable drugs. 14th ed. Bethesda, MD: American Society of Health-System Pharmacists; 2007:372-86. a.[drugs.com]

Etiology

  • Castleman's disease is a rare benign condition of uncertain etiology, with several forms. It is postulated that a dysregulated inflammatory response may play a role in the pathogenesis of this disease.[ncbi.nlm.nih.gov]
  • The main aim of any intervention is to relieve the symptoms and exclude other etiological factors. Keywords: Androgen, drug, estrogen, gynecomastia, surgery How to cite this article: Cuhaci N, Polat SB, Evranos B, Ersoy R, Cakir B.[doi.org]
  • Helicobacter pylori infection: a novel risk factor in the etiology of gastric cancer. J Natl Cancer Inst. 1991; 83:1702-3. 238. Parsonnet J. Helicobacter pylori and gastric cancer. Gastroenterol Clin North Am. 1993; 22:89-104. 239. Correa P.[drugs.com]

Epidemiology

  • Men were followed up for subsequent prostate cancer by linkage to the Surveillance, Epidemiology and End Results cancer registry. We identified 548 incident invasive prostate cancer cases diagnosed from baseline to December 31, 2003.[ncbi.nlm.nih.gov]
  • Epidemiology, 8 : 126 -131, 1997. Mandelson M. T., Wagner E. H., Thompson R. S. PSA Screening: a public heath dilemma. Annu. Rev. Public Health, 16 : 283 -306, 1995. View Abstract[cebp.aacrjournals.org]
  • Google Scholar Medline ISI Hulley SB, Cummings SR Designing clinical research: An epidemiologic approach. Williams and Wilkins : Baltimore, 1988, p. vi. Google Scholar Tan EM, et al. The 1982 revised criteria for the classification of SLE.[doi.org]
  • Epidemiology , 8 : 126 -131, 1997 . Mandelson M. T., Wagner E. H., Thompson R. S. PSA Screening: a public heath dilemma. Annu. Rev. Public Health , 16 : 283 -306, 1995 . View Abstract[cebp.aacrjournals.org]
  • Epidemiology, transmission, and pathogenesis. Clin Lab Med 2000 ; 20: 235 – 55. Google Scholar Crossref Medline ISI 2. Allen, AL, Siegfried, EC. What's new in human papillomavirus infection. Curr Opin Pediatr 2000 ; 12: 365 – 9.[doi.org]
Sex distribution
Age distribution

Pathophysiology

  • We discuss the pathophysiology, diagnosis, and treatment.[ncbi.nlm.nih.gov]
  • The pathophysiology of gynecomastia is also discussed in detail for each of the drugs found to have a good or fair evidence of association with gynecomastia.[doi.org]
  • Gastroesophageal reflux disease in adults: pathophysiology, diagnosis, and management. J Fam Pract. 1992; 35:673-81. 298. Hixson LJ, Kelley CL, Jones WN et al. Current trends in the pharmacotherapy for gastroesophageal reflux disease.[drugs.com]

Prevention

  • Further, these data provide little evidence to support the previously hypothesized preventive effect of cimetidine on risk of prostate cancer.[ncbi.nlm.nih.gov]
  • This prevents the indigestion symptoms. Antacids work by neutralizing the stomach acid that is already present. Antacids can relieve the pain of indigestion, but cannot prevent it.[sharecare.com]
  • To prevent symptoms, it is taken within 30 minutes before eating or drinking foods that cause heartburn.[medlineplus.gov]
  • The prevention of upper gastrointestinal tract bleeding in patients in an intensive care unit. Surg Gynecol Obstet. 1981; 153:214-20. 167. Hastings PR, Skillman JJ, Bushnell LS et al.[drugs.com]

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