We report two patients who presented with this circadian rhythm disorder, and were then diagnosed with a Parkinsonian syndrome. The cases. [ncbi.nlm.nih.gov]

• Heat Intolerance

  She referred episodes of heat intolerance when ambient temperature was around 35 degrees C. Skin biopsies of both forearms and left axilla revealed atrophy and morphologic changes of eccrine glands. [ncbi.nlm.nih.gov]

• Anhidrosis

  We evaluated the CRT in a 45-year-old female with a lack of sweating since birth because of congenital generalized anhidrosis. She referred episodes of heat intolerance when ambient temperature was around 35 degrees C. [ncbi.nlm.nih.gov]

• Compulsive Disorder

  The main augmentation strategy in the treatment of obsessive-compulsive disorder (OCD) is the addition of low-dose dopamine antagonists, such as risperidone. [ncbi.nlm.nih.gov]

• Psychiatric Symptoms

  This review summarizes the current literature regarding the association between circadian rhythm and mood regulation from a chronobiological perspective, and may provide insight into therapeutic approaches to target psychiatric symptoms in neurodegenerative [ncbi.nlm.nih.gov]

• Hot Flushes

  Circadian rhythm was detected in the daily pattern of hot flushes, with a peak in the afternoons. [ncbi.nlm.nih.gov]

• Nocturia

  In this article, we describe how age-related changes in sleep depth and continuity and age-related changes in circadian rhythm amplitude may contribute to nocturia, and how nocturia in turn leads to sleep disruption. [ncbi.nlm.nih.gov]

• Somnolence

  EXCESSIVE DAYTIME SOMNOLENCE Excessive daytime somnolence (EDS) is defined as the inability to stay awake or alert throughout the course of the day, resulting in sleepiness or inadvertent dozing during passive (reading, watching television) or active [doi.org]

• Involuntary Movements

  One explanation for this is the occurrence of 'break through' involuntary movements during sleep in the HD patients, which are incorrectly assessed as wakeful periods by the activity monitor algorithms. [ncbi.nlm.nih.gov]

• Dysarthria

  A 47-year-old man, who was being evaluated for presurgical investigation for refractory temporal lobe epilepsy, presented with complaints suggestive of dysarthria, bradykinesia of limbs and frequent falls for 5 months. [ncbi.nlm.nih.gov]

• Motor Symptoms

  In Parkinson's disease (PD), DAergic neurons in the substantia nigra pars compacta progressively degenerate leading to motor dysfunction. Patients with PD also exhibit non-motor symptoms, including sleep disorder and neuropsychiatric disorders. [ncbi.nlm.nih.gov]

Placement of a urinary catheter early in the workup of a patient with ARF not only allows diagnosis and treatment of urethral and bladder outlet urinary obstruction but also allows for accurate measurement of urine output. [emedicine.com]

• Gliosis

  Although, the number of AVP-positive neurons was decreased in neither the supraoptic nucleus nor the paraventricular nucleus, the number of AVP-positive neurons in the SCN was decreased and gliosis was present in the SCN. [ncbi.nlm.nih.gov]

CONCLUSIONS: The main problem in the treatment of CRSWD is an invalid diagnosis. Hypnotics and/or psychostimulants are often used instead of chronotherapeutic interventions, what can alleviate symptoms but is not an effective treatment. [ncbi.nlm.nih.gov]

Circadian rhythm disruption by shift work is associated with greater risk for cancer development and poor prognosis, suggesting a putative tumor-suppressive role for circadian rhythm homeostasis. [ncbi.nlm.nih.gov]

The following provide an outlook into some sleep disorders: Jet lag: This is a transient condition that has a good prognosis. [emedicinehealth.com]

Prognosis Because most cases of community-acquired acute renal failure (ARF) are secondary to volume depletion, as many as 90% of cases are estimated to have a potentially reversible cause. [emedicine.com]

Pruritus and scratching could lead to sleep disruption but is unlikely the sole etiology. The circadian rhythm of cytokines, the immune system, and skin physiology such as transcutaneous water loss and skin blood flow might also play a role. [ncbi.nlm.nih.gov]

This information can be used clinically to help differentiate prerenal failure from other etiologies of ARF. [emedicine.com]

Author information 1 Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD. 2 Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY. 3 Epidemiology Research Program, American Cancer Society [ncbi.nlm.nih.gov]

Epidemiology of the human circadian clock. Sleep Med Rev, 11(6), 429-438. - summary of the basic MCTQ findings up to 2007, explanation of MSF vs. MSFsc Roenneberg, T., Allebrandt, K. V., Merrow, M., & Vetter, C. (2012). Social jetlag and obesity. [thewep.org]

Khaw, Daytime Napping and the Risk of All-Cause and Cause-Specific Mortality: A 13-Year Follow-up of a British Population, American Journal of Epidemiology, 179, 9, (1115), (2014). [doi.org]

However, the pathophysiology of sleep disturbance in children with AD is poorly understood, and there is no consensus on how to manage sleep problems in these patients. [ncbi.nlm.nih.gov]

The ability to identify agents that can disrupt central and/or peripheral biological clocks, and agents that can prevent or mitigate the effects of circadian disruption, has significant implications for prevention of chronic diseases. [ncbi.nlm.nih.gov]