The most frequent sign was nystagmus, which was observed in 47 subjects. Gait ataxia was the second most frequent sign (in 36 subjects) and was associated with limb ataxia in 27 subjects, nystagmus in 19, and dysarthria in 9 ( Figure 2 ). [nejm.org]

Some affected individuals develop mild but permanent difficulty coordinating movements (ataxia), which may worsen with time, and rapid, involuntary eye movements called nystagmus. [icdlist.com]

Genetic testing may be of highest yield in people with early onset hemiplegic migraine associated with eye movement abnormalities (nystagmus), seizures or other persistent neurologic symptoms (ataxia). [americanmigrainefoundation.org]

Mutations in this gene also produce episodic ataxia type 2 (EA-2), another autosomal dominant paroxysmal cerebral disorder characterized by acetazolamide-responsive attacks of cerebellar ataxia and migraine-like symptoms, interictal nystagmus, and cerebellar [medlink.com]

About 20 percent of people with this condition develop mild but permanent difficulty coordinating movements (ataxia), which may worsen with time, and rapid, involuntary eye movements called nystagmus. [ghr.nlm.nih.gov]

[…] hemiplegic migraine and cerebellar signs. [nejm.org]

You can help by adding to it. ( August 2017 ) Diagnosis [ edit ] Diagnostic criteria require motor symptoms and at least one visual, sensory, or speech symptom, resembling basilar migraine. [4] They may also be associated with cerebellar signs. [5] Investigations [en.wikipedia.org]

It is well described that FHM1 can present with cerebellar signs, but parkinsonism has not previously been reported in FHM1 or EA2 even though parkinsonism has been described in SCA6. [karger.com]

A G301R Na /K   -ATPase mutation causes familial hemiplegic migraine type 2 with cerebellar signs. Neurogenetics. 2004;5:177–85. PubMed CrossRef Google Scholar 27. Dichgans M, Freilinger T, Eckstein G, et al. [link.springer.com]