Clonorchiasis usually presents with chronic gastrointestinal disturbances or cholangiocarcinoma. We describe a rare acute presentation of clonorchiasis in a child with diarrhea and liver abscess. [ncbi.nlm.nih.gov]

• Chills

  Symptoms of Clonorchiasis include heavier infections can cause fever, chills, epigastric pain, tender hepatomegaly, mild jaundice, and eosinophilia. [omicsonline.org]

  In the acute phase, heavier infections can cause fever, chills, epigastric pain, tender hepatomegaly, mild jaundice, and eosinophilia. Later, diarrhea may occur. [msdmanuals.com]

  An onset with chills and fever indicates bacterial infection from biliary obstruction. Patients with clonorchiasis may die from a variety of complications, including biliary obstruction, bacterial cholangitis, pancreatitis, and cholangiocarcinoma. [histopathology-india.net]

• Painless Jaundice

  A 26-yr-old male presented with complaints of fatigue, weight loss and painless jaundice. The history was significant for frequent ingestion of raw freshwater fish. [ncbi.nlm.nih.gov]

• Swinging Fever

  A 42-year-old Chinese woman developed 3 weeks of swinging fever, rash, malaise, and discomfort at the right upper quadrant of the abdomen. Acute Clonorchis sinensis infection eventually became evident and the patient responded to praziquantel. [ncbi.nlm.nih.gov]

• Abdominal Pain

  The patient presented with complaints of abdominal pain and was found on imaging to have clonorchiasis infestation of the bile ducts. [ncbi.nlm.nih.gov]

  In the acute phase of the disease, heavier infections can lead to fever, episodes of chills, abdominal pain, nausea, hepatomegaly (tender in nature), jaundice (mild to moderate), diarrhea, and eosinophilia. [xpertdox.com]

  The signs and symptoms of Clonorchiasis may include: Abdominal pain, nausea, and diarrhea Any pathology (infection) of the bile duct and adjacent organs can cause abdominal pain (particularly under the rib cage to the right), jaundice, fever, or chills [dovemed.com]

• Nausea

  A 54-year-old Korean woman suffered from hypersensitive reactions, such as nausea, dyspnea, rash, and urticaria after taking the first dose of praziquantel to treat clonorchiasis. [ncbi.nlm.nih.gov]

  The common symptoms of clonorchiasis include jaundice, liver tenderness and enlargement, nausea, diarrhea, vomiting, abdominal pain, loss of appetite, and anisakiasis. [biology-online.org]

  The early stage of Clonorchiasis, known as the acute stage, manifests as nausea, eosinophilia, diarrhea, and abdominal pain. Untreated, the infection progresses and can develop into pancreatitis, cholangitis, cholangiocarcinoma, or cholelithiasis. [medic8.com]

• Right Upper Quadrant Pain

  Two patients with habit of eating infected raw or undercooked freshwater fish were hospitalized due to right upper quadrant pain and jaundice. [ncbi.nlm.nih.gov]

  In humans, acute clonorchiasis may be asymptomatic or scarcely symptomatic in light infections, but if the number of worms is significant (up to several thousands), fever and right upper-quadrant pain are not infrequent and may be associated with intermittent [who.int]

• Hepatomegaly

  Symptoms of Clonorchiasis include heavier infections can cause fever, chills, epigastric pain, tender hepatomegaly, mild jaundice, and eosinophilia. [omicsonline.org]

  In the acute phase, heavier infections can cause fever, chills, epigastric pain, tender hepatomegaly, mild jaundice, and eosinophilia. Later, diarrhea may occur. [msdmanuals.com]

  In the acute phase of the disease, heavier infections can lead to fever, episodes of chills, abdominal pain, nausea, hepatomegaly (tender in nature), jaundice (mild to moderate), diarrhea, and eosinophilia. [xpertdox.com]

• Suggestibility

  Knowledge about C. sinensis infection gained from Thailand over the past decade suggests that the habit of eating raw freshwater fish is a major risk factor for infection. However, further information to confirm this is needed. [ncbi.nlm.nih.gov]

• Neglect

  Therefore,in the course of diagnosis of hepatic and gall diseases, we cannot neglect parasite infections such as clonorchiasis. [ncbi.nlm.nih.gov]

  Clonorchiasis, a neglected tropical disease usually acquired by eating undercooked freshwater fish, affects an estimated 15 million people around the globe. More than 85% of cases are concentrated in China. [eurekalert.org]

  Clonorchiasis is caused by infection with food-borne liver fluke, namely Clonorchis sinensis, which is also considered to be a neglected tropical disease. [semanticscholar.org]

26099940 ) Kang J.M....Na B.K. 2015 18 Identification and characterization of Clonorchis sinensis cathepsin B proteases in the pathogenesis of clonorchiasis. ( 26691339 ) Chen W....Yu X. 2015 19 In vivo diagnosis of clonorchiasis during cholangioscopy for workup [malacards.org]

The present results confirm that DDIHD and IPDE persist but FEFGB decreases significantly at 1 year after treatment. In a heavy endemic area, the sonographic finding of FEFGB may suggest active clonorchiasis 1 year after treatment. [ncbi.nlm.nih.gov]

BACKGROUND: Intrahepatic cholangiocarcinoma caused by clonorchiasis (CICC) has a poor prognosis, and there have been insufficient studies regarding risk and prognostic factors. We aimed to identify CICC-associated factors. [ncbi.nlm.nih.gov]

This practice must be strictly eliminated to prevent Clonorchiasis What is the Prognosis of Clonorchiasis? (Outcomes/Resolutions) A proper and timely diagnosis and treatment can lead to a good prognosis. [dovemed.com]

Prognosis Light infections may resolve spontaneously within one year, even without treatment. However the prognosis may be grave in patients with heavy infection. Immunocompromised hosts may be at an increased risk of complications. [patient.info]

Association of C. sinensis infection with CCA CCA, usually with poor prognosis, is a primary hepatic malignancy arising from bile duct epithelium and ranks the second most common primary hepatic malignancy[ 73 – 75 ]. [idpjournal.biomedcentral.com]

Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10coded.com]

Cholangiocarcinoma was related to clonorchiasis, which suggested an etiological role for the parasite. [ncbi.nlm.nih.gov]

(Etiology) Clonorchiasis is a foodborne infection caused by Clonorchis sinensis or Chinese liver fluke, a parasitic worm which grows and resides in the bile ducts of the liver in humans and fish-eating mammals. [dovemed.com]

By analysis of epidemiological data, we found that the ecologic environment was favorable for the epidemiology of clonorchiasis. Most patients with clonorchiasis were lack of knowledge about the disease. [ncbi.nlm.nih.gov]

In this article, the radiologic findings, including cholangiography, sonography, and CT of clonorchiasis are reviewed in light of the pathophysiology of the disease. [ncbi.nlm.nih.gov]

Clonorchiasis pathophysiology Clonorchiasis is infection with the liver fluke Clonorchis sinensis. Infection is acquired by eating undercooked freshwater fish. [omicsonline.org]

Pathophysiology Adult forms of C. sinensis live in the bile ducts. Eggs are passed in the stool and ingested by snails. Cercariae (free-swimming larvae) released from infected snails subsequently infect a variety of freshwater fish. [merckmanuals.com]

Praziquantel is the treatment of choice and has been considered for preventive chemotherapy. Tribendimidine showed good safety and therapeutic profiles in phase 2 trials and warrants further investigation. [ncbi.nlm.nih.gov]