These symptoms are always present at birth, but might not be noticeable right away. [texaschildrens.org]

Most CLOVES patients present with a soft fatty mass at birth, often visible on one or both sides of the back, legs and/or abdomen. [en.wikipedia.org]

These abnormalities are typically present at birth. The most common features are: 1. Fatty overgrowth. Soft fatty masses of variable size are noted at birth and can be located in the back, flanks, axilla, abdomen and buttocks. [rarediseases.org]

Treatment is based on the signs and symptoms present in each person.[2][3] Last updated: 10/5/2016 This table lists symptoms that people with this disease may have. For most diseases, symptoms will vary from person to person. [rarediseases.info.nih.gov]

• Surgical Procedure

  Large veins and lymphatic malformations should be treated with minimally invasive procedures such as sclerotherapy, embolization and laser treatment before undergoing surgical procedures due to the risk of vein thrombosis. [rarediseases.org]

• Splenomegaly

  […] first and second toes Wide space between 1st, 2nd toes Wide space between first and second toes Wide-spaced big toe Widely spaced 1st-2nd toes Widely spaced first and second toes Widened gap 1st-2nd toes Widened gap first and second toe [ more ] 0001852 Splenomegaly [rarediseases.info.nih.gov]

• Heart Failure

  There may be life-threatening problems due to the overgrowth pushing on vital organs or because the increased blood vessel growth can lead to heart failure. The syndrome affects about 150 people worldwide. [texaschildrens.org]

The doctor will put together a treatment plan for your child. Related articles PIK3CA-related segmental overgrowth [texaschildrens.org]

You may also want to contact a university or tertiary medical center in your area, because these centers tend to see more complex cases and have the latest technology and treatments. [rarediseases.info.nih.gov]

Goals CLOVES Syndrome Community is working to create a patient-led collaborative research network in order to broaden the medical knowledge base, accelerate treatment options and improve quality of life for people with CLOVES and PIK3CA Related Conditions [clovessyndrome.org]

Standard Therapies Treatment The management of CLOVES syndrome can be very challenging and requires an interdisciplinary team of physicians with experience in overgrowth and vascular anomalies. [rarediseases.org]