Presentation
PRINCIPAL FINDINGS: In the present work, we demonstrate a consistent procoagulant profile on 40 reactional and non-reactional multibacillary leprosy patients. [ncbi.nlm.nih.gov]
Collection includes both citations and many full-text, downloadable documents from mid-1900s to present. AULIMP - Air University Library Index to Military Periodicals. [dtic.mil]
Hematological
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Easy Bruising
A history of prolonged bleeding from minor wounds, easy bruising or a family history of bleeding disorders should be asked in those patients with epistaxis. Thrombocytopenia is the common cause of the epistaxis. [tkbbv.org.tr]
However, the main signs include: unexplained and easy bruising heavy menstrual bleeding frequent nosebleeds excessive bleeding from small cuts or an injury bleeding into joints Schedule an appointment with your doctor right away if you have one or more [healthline.com]
Symptoms include easy bruising, bleeding in small cuts that stops and starts, abnormal bleeding after surgery, and abnormally heavy menstrual bleeding. [medical-dictionary.thefreedictionary.com]
Jaw & Teeth
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Bleeding Gums
epistaxis, bleeding gums) Petechia, purpura, superficial ecchymoses Menorrhagia Prolonged and excessive bleeding after surgery Features of secondary hemostasis disorders (i.e., clotting defects) Minutes to hours after trauma Deep tissue bleeding (e.g [amboss.com]
Skin
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Purpura
[…] and other hemorrhagic conditions D69.0 Allergic purpura D69.1 Qualitative platelet defects D69.2 Other nonthrombocytopenic purpura D69.3 Immune thrombocytopenic purpura D69.4 Other primary thrombocytopenia D69.42 Congenital and hereditary thrombocytopenia [icd10data.com]
Blood smear from a patient with thrombocytopenic thrombotic purpura, due to deficiency of ADAMTS-13. The arrows indicate schistocytes generated by mechanical damage to red cells. [ncbi.nlm.nih.gov]
Face, Head & Neck
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Epistaxis
The most common hereditary bleeding disorder associated with epistaxis is vonWillebrant disease(vWD). These patients are manifests clinically with epistaxis, and excessive bleeding despite local treatment. [tkbbv.org.tr]
epistaxis, petechiae, gastrointestinal bleeding) is associated more with platelet disorders, while bleeding into potential spaces (e.g., hemarthrosis, muscular bleeding) is more characteristic of coagulation defects. [amboss.com]
Bleeding may occur also from the same lesions seen in the general population such as peptic ulcer, epistaxis, gingivorrhagia, bruising or from invasive procedures. [elsevier.es]
As the platelet counts are usually 50x10 9 L -1 there is an increased incidence of bruising, epistaxis and gingival bleeding. Treatment aims at increasing platelet count. [frca.co.uk]
Patients with only spontaneous petechiae or bruising at venipuncture sites were considered to have mild bleeding; those with mucosal bleeding that did not affect the hematocrit were considered to have moderate bleeding; and those with epistaxis or gastrointestinal [academic.oup.com]
Urogenital
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Hematuria
INCREASED VASCULAR FRAGILITY seldom serious skin bruises, dependent petechiae, gum bleeding, hematuria, nosebleeds, GI bleeds. Infections - damage endothelium Amyloidosis Collagen problems Immune-complex deposition in vessel walls 7. [slideshare.net]
Aprotinin may cause anaphylactic responses and lysine analogues should not be used in patients with hematuria since obstructive clots in the urinary tract have occurred. [ncbi.nlm.nih.gov]
Workup
Diagnostic workup of patients with acquired von Willebrand syndrome: a retrospective single-centre cohort study. J Thromb Haemost. 2008;6(4):569–576. 88. Tefferi A, Barbui T. [dovepress.com]
Treatment
The treatment of the two conditions is very different. [ncbi.nlm.nih.gov]
Prognosis
While the chapters discuss definitions, pathophysiology, clinical course, complications, and prognosis, the primary emphasis is devoted to patient management. [books.google.com]
Predicting the prognosis of chronic liver disease: an evolution from child to MELD. Mayo end-stage liver disease. Hepatology 2001; 33: 473-5. 8.Garrison RN, Cryer HM, Howard DA, Polk HC. [pacificejournals.com]
Additional therapeutic efforts, like administration of heparin or antifibrinolytic drugs, have failed to improve the prognosis of patients with severe coagulation abnormalities. [ncbi.nlm.nih.gov]
Many lung cancers of all histological types (adenocarcinomas being the leas in the clinical course of the disease in terms of prediction and prognosis. [md-medicaldata.com]
Prognosis The prognosis for patients with mild forms of coagulation disorders is normally good. Many people can lead a normal life and maintain a normal life expectancy. [medical-dictionary.thefreedictionary.com]
Etiology
The etiology probably involves successive vascular occlusions, in which hypercoagulable disorders may play a role. We evaluated the etiologic role of thrombophilia in Legg-Calvé-Perthes disease in a pediatric population. [ncbi.nlm.nih.gov]
Thirteen etiologies were identified as possible factors for the emergence of secondary osteonecrosis, and 1 study describes cases of osteonecrosis and M Perthes (Table 2 ). 46 Table 2: Etiologic Factors for Secondary Osteonecrosis Localization of Osteonecrosis [healio.com]
Methods Analysis of key baseline characteristics, etiology, coagulation and hematological tests, use of blood products, thrombotic complications, and clinical outcomes during the first ICU week. Results We studied 62 ALF patients. [onlinelibrary.wiley.com]
Epidemiology
This epidemiologic information and practice variability provide baseline data for the design and powering of interventional studies. The full text of this article hosted at iucr.org is unavailable due to technical difficulties. [onlinelibrary.wiley.com]
Acute upper gastrointestinal bleeding in patients with liver cirrhosis and in noncirrhotic patients: epidemiology and predictive factors of mortality in a prospective multicenter population-based study. [pacificejournals.com]
Epidemiology of trauma deaths: a reassessment. J Trauma. 1995;38:185–193. [PubMed] [Google Scholar] 2. Kauvar DS, Lefering R, Wade CE. [ncbi.nlm.nih.gov]
The reader may refer to excellent reviews and guidelines on these topics.2,3 For the purpose of simplicity, we deal with each leukemia type with a case vignette, followed by epidemiology, pathophysiology, and management issues. [oncologynurseadvisor.com]
Von Willebrand disease (VWD) VWD is the most common hereditary bleeding disorder with, according to epidemiological studies, an estimated prevalence worldwide as high as 1 to 2% in the general population [ 5 - 7 ]. [wrbd.org]
Pathophysiology
This review addresses the pathophysiology of coagulation abnormalities in HF, examines the available evidence regarding the use of anticoagulants and antiplatelet agents in HF, and discusses its therapeutic implications. [ncbi.nlm.nih.gov]
Kwaan Springer Science & Business Media, ٢١/٠٤/٢٠٠٩ - 339 من الصفحات Coagulation in Cancer informs professionals working in the field of cancer about the pathophysiologic mechanisms of cancer-related thrombosis and bleeding. [books.google.com]
Discussion Our data shed light on the pathophysiology of the progression of E. coli O157:H7 infection to the hemolytic–uremic syndrome. [nejm.org]
Prevention
Among 1,032 patients evaluated we found that 534 coagulation tests were needed to prevent one case of bleeding associated with an abnormal coagulation test result. Copyright 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. [ncbi.nlm.nih.gov]
It provides assistance in recognizing the various bleeding and clotting disorders associated with cancer and includes current recommendations for the management of hemorrhage, and prevention and treatment of thrombosis in the patient with malignancy. [books.google.com]
Access personal reporting Related Content This Book Next chapter Prevention of Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis By Atsushi Sofuni and Takao Itoi Related Book First chapter Acute Biliary Pancreatitis By Mehmet Ilhan and [intechopen.com]
Anti–TNF-α treatment prevented lipopolysaccharide (LPS)-induced increases in tissue factor and PAI-1 expression in the lungs. [atsjournals.org]