Cogan syndrome is a rare disorder characterized by recurrent inflammation of the front of the eye (the cornea ) and often fever, fatigue, and weight loss, episodes of vertigo (dizziness), tinnitus (ringing in the ears) and hearing loss. [en.wikipedia.org]

Usually, within a few hours to a few weeks evidence of eighth nerve involvement appears, manifested by tinnitus, nausea, vomiting, vertigo, and bilateral progressive loss of hearing. [jamanetwork.com]

The vestibuloauditory manifestations consist of a Ménière’s-like disease including vertigo, nausea, vomiting, tinnitus, and hearing loss. [jrheum.org]

The administration of a combined immunosuppressive treatment resolved ocular inflammation, dizziness, nausea, and vertigo but gave little results in controlling progressive hearing loss. [ojrd.biomedcentral.com]

In the past month she also developed vertigo, nausea, otalgia, diminished appetite, as well as progressively worsening vision. Acetaminophen provided moderate relief from her pain. [webeye.ophth.uiowa.edu]

Otorhinolaryngology, bService of Internal Medicine I, cService of Ophthalmology, dService of Pathology Abstract Typical Cogan's syndrome is a rare disease of young adults consisting of flares of interstitial keratitis and sudden onset of Ménière-like attacks (nausea [pmj.bmj.com]

The systemic manifestations of Cogan’s syndrome are fever, headache, myalgia, arthralgia, arthritis, gastrointestinal symptoms and skin lesions such as rash, vasculitis and vitiligo. [medcraveonline.com]

Clinically, vasculitis has been reported to affect the skin, kidneys, subcutaneous nodules, distal coronary arteries, and muscles. [ajnr.org]

Slit-lamp examination revealed conjunctival hyperemia and peripheral corneal opacification, with inflammation and crystalline deposits on the corneal stroma, findings that are consistent with interstitial keratitis. [nejm.org]

Conjunctival hyperemia, bilateral cataract, and interstitial keratitis were detected with a slit lamp examination. Pure tone audiogram (PTA) and auditory brain stem response (ABR) showed bilateral sensorineural hearing loss. [hindawi.com]

Examination reveals ciliary injection with mild iritis and discrete fluffy opacities in the deep portion of the corneal stroma. Corneal ulceration does not occur and vascularisation is now unusual. [pubs.sciepub.com]

THE COGAN syndrome is characterized by sudden onset of photophobia, ocular pain, blurring of vision, and blepharospasm. [jamanetwork.com]

It can start with eye inflammation (red and painful eyes irritated by the light), with hearing loss and vertigo, or with both within a one month period of time. [vasculitisfoundation.org]

She denied any hearing loss, diplopia, fever, cough, rhinorrhea, otorrhea, tinnitus, and vomiting. [webeye.ophth.uiowa.edu]

Usually, within a few hours to a few weeks evidence of eighth nerve involvement appears, manifested by tinnitus, nausea, vomiting, vertigo, and bilateral progressive loss of hearing. [jamanetwork.com]

The audiovestibular symptoms, tinnitus, sensorineural hearing loss and acute episodes of vertigo, are usually bilateral. Cogan's syndrome is a disorder of young adults, the average age of onset being 25 years. [pmj.bmj.com]

Cogan syndrome is a systemic disease manifesting interstitial keratitis, sensorineural hearing loss, tinnitus, and rotatory vertigo. Renal complications of this syndrome are very rare. [ncbi.nlm.nih.gov]

Shortly following these ocular (eye) symptoms, patients develop bilateral audiovestibular (ear) symptoms, including hearing loss, vertigo (dizziness) and tinnitus (ringing in the ears). [aarda.org]

The histopathologic manifestations appear to explain the audiovestibular dysfunction that has been reported in Cogan's syndrome, including bilateral fluctuating hearing loss, tinnitus, and severe vertigo. [ 2, 4 ]. [pubs.sciepub.com]

However, every attempt to decrease and stop the steroid treatment has been followed by fluctuating hearing loss and conjunctivitis. [pediatrics.aappublications.org]

Adverse effects of glucocorticoids are well known and include glucose intolerance, diabetes, easy bruising, increased infections, rounded faces, loss of calcium from bones, central nervous system effects (particularly at high dose), and thinning of skin [vasculitisfoundation.org]

At 18, the patient developed rotatory vertigo, a sense of ear fullness, and sensorineural hearing loss. The patient was diagnosed with Cogan syndrome. [ncbi.nlm.nih.gov]

42-year-old Female with Interstitial Keratitis and Vertigo May 24, 2007, updated Nov 20, 2007 Chief Complaint: Red left eye for the past two months with recent onset of vertigo and otalgia. [webeye.ophth.uiowa.edu]

Vertigo can also be severe. Vasculitis signs and symptoms can be present at presentation or may develop later in the course of the syndrome. [vasculitisfoundation.org]

The patient was treated successfully with topical steroids but over the following months, he developed vertigo, sensorineural hearing loss (SNHL) and generalized vasculitis. This is the first reported case of CS in Jordanian population. [ajol.info]

Usually, within a few hours to a few weeks evidence of eighth nerve involvement appears, manifested by tinnitus, nausea, vomiting, vertigo, and bilateral progressive loss of hearing. [jamanetwork.com]

Shortly following these ocular (eye) symptoms, patients develop bilateral audiovestibular (ear) symptoms, including hearing loss, vertigo (dizziness) and tinnitus (ringing in the ears). [aarda.org]

Hain, MD Last update: 10/2002 Cogan's syndrome is defined as nonsyphilitic interstitial keratitis (an inflammation of the eye) and bilateral audiovestibular deficits (hearing problems and dizziness). [web.archive.org]

Along with eye inflammation, Cogan’s syndrome can cause dizziness, balance problems, tinnitus (ringing in the ears) and loss of hearing. [lvhn.org]

Cogan syndrome can lead to vision difficulty, hearing loss and dizziness. [en.wikipedia.org]

Its etiology includes infection and autoimmunity, Chlamydia psittaci has been isolated from a patient with Cogan's syndrome and serological evidence of a recent Chlamydia trachomatis infection was reported in 4 of 13 patients [ 6 ]. [pubs.sciepub.com]

Figure 2 Photomicrography of the conjunctiva section showing mild lymphocytic infiltration of the chorion Figure 1 Axial MRI of the inner ear showing hyperintensity within the membranous labyrinth on precontrast T1-weighted images when compared to the [pmj.bmj.com]

Blood test results were negative for antinuclear antibody, antinuclear cytoplasmic antibody, rheumatoid factor, rapid plasma reagin, and HLA-B27. The hepatitis serology finding was negative. [pubs.sciepub.com]

Additional laboratory tests, including complete blood count, urinalysis, serum electrolytes, creatinine, liver transaminases, angiotensin converting enzyme, HLA-B5, antinuclear antibodies, rheumatoid factor, anti-citrullinated protein antibodies, antiphospholipid [reumatologiaclinica.org]