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Collagenous Sprue
Non Gluten Sensitive Enteropathy Syndrome

Presentation

The present case suggests that CS should be considered as a differential diagnosis for intractable diarrhea, even in infants. [ncbi.nlm.nih.gov]

Atypical presentation of celiac disease was seen in patients across all grades of fibrosis. [nature.com]

Workup

Laboratory workup revealed normal stool analysis and TSH. He also tested negative for C.Diff, celiac disease antibodies, HIV, ANA, Hepatitis A, B and C. Initial EGD and colonoscopy were essentially normal. [shmabstracts.com]

Provides all the necessary tools to make a comprehensive diagnostic workup including data from ancillary techniques and molecular findings whenever appropriate. [books.google.com]

X-Ray

  • Pancreatic Calcification

    Non-alcoholic chronic pancreatitis with pancreatic calcification: Presenting manifestation of occult celiac disease. Can J Gastroenterol. 1994;8:319–22. [Google Scholar] 6. Tursi A, Brandimarte G, Giorgetti GM, et al. [ncbi.nlm.nih.gov]

Treatment

In addition, successful treatment with biological agents, such as infliximab, has been documented (32,33), although reports describing development of lymphoproliferative diseases, particularly T cell type hepatosplenic lymphomas, may temper this treatment [ncbi.nlm.nih.gov]

Prognosis

CS is historically associated with a poor prognosis (Marthey et al., 2014). However, histological and clinical improvements have been described in most studies with concomitant usage of corticosteroids and/or gluten-free diet (Marthey et al., 2014). [ncbi.nlm.nih.gov]

Prognosis still remains guarded with most patients due to progressive malnutrition often requiring steroid/immunosuppressive/total parenteral nutrition for survival. Collagenous sprue is a rare malabsorption disease with very poor prognosis. [shmabstracts.com]

Prognosis is usually dismal. (NCI Thesaurus) ALSO IN ENCYCLOPEDIA : [tititudorancea.com]

Etiology

Its exact etiology is still under investigation, and its relationship with classic celiac disease and other refractory, spruelike intestinal disorders remains controversial. [ncbi.nlm.nih.gov]

The aim of our study was to describe the etiology of collagenous sprue and provide objective histological criteria for diagnosis. [nature.com]

Epidemiology

The epidemiology of microscopic colitis: a population based study in Olmsted County, Minnesota. Gut. 2007; 56(4):504-508. 11. Olesen M, Eriksson S, Bohr J, Järnerot G, Tysk C. Microscopic colitis: a common diarrhoeal disease. [consultant360.com]

The epidemiology of microscopic colitis: a 10-year pathology-based nationwide Danish cohort study. Scand J Gastroenterol. 2015;50(4):393–398. 16. Park YS, Baek DH, Kim WH, et al. [dovepress.com]

The epidemiology of microscopic colitis: a population based study in Olmsted County, Minnesota. Gut. 2007 Apr. 56(4):504-8. [Medline]. Pardi DS, Ramnath VR, Loftus EV Jr, Tremaine WJ, Sandborn WJ. [emedicine.medscape.com]

Pathophysiology

The association between autoimmune diseases and olmesartan associated enteropathy is consistent with the emerging evidence supporting an immune-based pathophysiology. [elsevier.pt]

Pathophysiology Daum and associates reported that increased collagen synthesis in the absence of adequate fibrolysis appears to be the pathophysiologic mechanism leading to the broadened subepithelial collagen band in CS. 47 This mechanism is seen in [ncbi.nlm.nih.gov]

It shows the specific features of the pathophysiology, diagnosis, and treatment of MAS in small bowel diseases. 2016: Terapevticheskiĭ Arkhiv # 5 COMPARATIVE STUDY Nan Lan, Bo Shen, Lisi Yuan, Xiuli Liu BACKGROUND: Collagenous sprue (CS) is a rare form [readbyqxmd.com]

Pathophysiology The characteristic feature of lymphocytic colitis (LC) is an infiltration by lymphocytes into the colonic epithelium. [emedicine.medscape.com]

[…] represent increased diagnostic activity. 15 A Korean study of chronic diarrhea detected CC in 4% of patients similar to rates recorded in the western world 16 and has been reported with lower prevalence rates in Indian and Malaysian studies. 17, 18 Pathophysiology [dovepress.com]

Prevention

In cases of diet-refractory 'coeliac disease' it is therefore essential to consider collagenous sprue to initiate treatment at an early stage to prevent the fibrotic progression. [ncbi.nlm.nih.gov]

A means for preventing deposits for use in the polymerization of VCM and other vinyl monomers has been found that is very effective in preventing the formation of deposits on reactor components that come in contact with the VCM. [google.sr]

In cases of diet-refractory ‘coeliac disease’ it is therefore essential to consider collagenous sprue to initiate treatment at an early stage to prevent the fibrotic progression. [casereports.bmj.com]

Patient Recruitment Office: Tollfree: (800) 411-1222 TTY: (866) 411-1010 Email: [email protected] For information about clinical trials sponsored by private sources, contact: www.centerwatch.com Supporting Organizations Centers for Disease Control and Prevention [rarediseases.org]

It's caused by problems in the blood vessels that, in turn, prevent the bowel from getting enough blood. [crohnscolitisfoundation.org]

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