Other less common pathologies responsible for this presentation include: Ectodermal dysplasia, Sjögren Larsen syndrome, Comel-Netherton syndrome Gaucher Disease type 2, Hay-Well syndrome, Trichothyodystrophy, Neutral lipid storage disease, etc.3 Genetically [ncbi.nlm.nih.gov]

Treatment may also include pain relief and mild topical steroids to reduce secondary inflammation. Conclusion Collodion baby probably is underreported condition with cases which have mild presentation not getting reported. [ncbi.nlm.nih.gov]