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Colonic Disease
Colonic Diseases

Presentation

Fistula from the colon to the bladder How would a colovesicular fistula present? Air or stool would be present in the bladder --Pneumaturia [quizlet.com]

Normal findings were present in 42.4%. [ncbi.nlm.nih.gov]

In patients refractory to steroids and/or anti-TNF vedolizumab is an appropriate alternative [EL1] Further information When reviewing this algorithm, bear in mind the following: Course of disease – initial presentation, frequency & severity of flares [e-guide.ecco-ibd.eu]

In Canada, despite the multicultural and ethnic mix, the incidence of this disease presented to surgery is rather low. Single diverticula are usually present in young patients and are prone to complication. [bmcresnotes.biomedcentral.com]

Entire Body System

  • Weight Loss

    Of the 21 variables selected for use in the database, 6 showed statistically significant differences in terms of the absence or presence of malignant disease: age, absence of previous similar episodes, weight loss, rectal bleeding, lack of improvement [ncbi.nlm.nih.gov]

    After controlling these infections, she continued to complain of diarrhea (>10 bowel movements per day) with further weight loss. [acgcasereports.gi.org]

    Weight loss and fatigue often accompany colon cancer, Crohn’s disease and ulcerative colitis. A person with Crohn’s disease or diverticulitis may also run a fever. [livestrong.com]

    Bleeding from the rectum, weight loss, joint pain, skin problems and fever may also occur. Children with the disease may have growth problems. [icd10data.com]

    Symptoms of IBD Symptoms of IBD include: pain, cramps or swelling in the tummy recurring or bloody diarrhoea weight loss extreme tiredness Not everyone has all of these symptoms, and some people may have additional symptoms, including fever, vomiting [nhs.uk]

  • Weakness

    Sometimes if the colon is weak and sluggish, there may be no bowel movement for several days following a colonic. However, this is not due to the colonic, but because of the weakness of the colon. Rarely is diarrhea or loose bowels experienced. [hippocratesinst.org]

    […] diarrhea, constipation, or narrowing of the stool, that lasts for more than a few days A feeling that you need to have a bowel movement that is not relieved by doing so Rectal bleeding Dark stools, or blood in the stool Cramping or abdominal (belly) pain Weakness [cancer.org]

    Diverticulosis : Small weak areas in the colon's muscular wall allow the colon's lining to protrude through, forming tiny pouches called diverticuli. Diverticuli usually cause no problems, but can bleed or become inflamed or infected. [webmd.com]

    They usually are invested with a thin layer of submucosa that is forced out through the weak points in the muscularis propria and the tips ending in the colonic subserosa [ 1, 3 ]. [bmcresnotes.biomedcentral.com]

  • Anemia

    Close-up colonoscopic view of a bleeding auto-amputated sigmoid polyp in a six year old who presented with rectal bleeding and anemia. [naspghan.org]

    Bleeding in ulcerative colitis and Crohn’s diseases can be severe enough to cause anemia, ColonSurgeryInfo.com states. Hemorrhoids can cause bleeding on the outside of the stool. [livestrong.com]

    […] colon involvement Diagrams / tables Images hosted on other servers: Comparison of patients with Crohn's disease vs tuberculosis Clinical features Symptoms: episodic mild diarrhea, fever, pain; may be precipitated by stress; if colon affected, may have anemia [pathologyoutlines.com]

    […] loose and narrow stools rectal bleeding or blood in the stool abdominal pain, cramps, bloating, or gas pain during bowel movements continual urges to defecate weakness and fatigue unexplained weight loss irritable bowel syndrome (IBS) iron deficiency anemia [medicalnewstoday.com]

    Aggarwal R, Gupta P, Chopra P, Nundy S (2013) Rectal cap polyposis masquerading as ulcerative colitis with pseudopolyposis and presenting as chronic anemia: a case study with review of literature. Saudi J Gastroenterol 19: 187-189. [omicsonline.org]

  • Familial Adenomatous Polyposis

    and familial adenomatous polyposis. [ncbi.nlm.nih.gov]

    This includes pre-cancerous polyps, ulcerative colitis, Crohn’s disease, and hereditary syndromes such as familial adenomatous polyposis (FAP) or hereditary non-polyposis colon cancer (HNPCC), also known as Lynch syndrome. [cancer.org]

    People who have these disorders, hereditary non-polyposis colon cancer (HNPCC [also known as Lynch syndrome]), Peutz-Jeghers syndrome, and familial adenomatous polyposis (FAP), are at increased risk of developing colon cancer. [verywell.com]

  • Pathologist

    After a polyp is removed, it will be tested for cancer by a pathologist. Sessile polyps are more likely to turn cancerous than pedunculated polyps. [verywell.com]

    A pathologist, or someone who specializes in tissue analysis, will check the polyps for cancerous cells. Colonic polyps are usually noncancerous and considered harmless. They often don’t cause any symptoms unless they’re very large. [healthline.com]

    If polyps are found in the colon, they are removed and sent to a pathologist for biopsy, an examination under a microscope that detects cancerous or precancerous cells. [medicalnewstoday.com]

    Biopsies (small pieces of tissue) may be taken from the lining of the colon and examined by a pathologist (a medical doctor specializing in the diagnosis of tissues) to help confirm the diagnosis. [emedicinehealth.com]

Gastrointestinal

  • Diarrhea

    Diarrhea : Stools that are frequent, loose, or watery are commonly called diarrhea. Most diarrhea is due to self-limited, mild infections of the colon or small intestine. [webmd.com]

    The most common clinical manifestations of colonic disease in AIDS are diarrhea, lower gastrointestinal bleeding, and abdominal pain. [ncbi.nlm.nih.gov]

    Fluid requirements increase during or after episodes of diarrhea and with exercise. Make sure you replenish losses of electrolytes from diarrhea. [ucsfhealth.org]

    Clostridium bacteria produce a toxin that causes diarrhea. This is an infection, and often there is a fever present. The diarrhea is usually not bloody. 2. [emedicinehealth.com]

  • Overeating

    Here, the ascending colon goes over into a sharp bend, the flexura coli dextra, into the colon transversum. Click and drag to move the 3D model around the page. [flexikon.doccheck.com]

    Over the tropical abundance of the woods of Vrindavan, He herds His cows as He keeps guard over the light in His devotees’ hearts (the Sanskrit word for cow is ‘go’, which also means effulgence). [exoticindiaart.com]

    The absence of a detectable relationship between adenoma number and age (over the range studied) suggests that most tumours may be initiated relatively early in the patient's life, perhaps at a time of particular susceptibility. [ncbi.nlm.nih.gov]

  • Constipation

    Constipation is a common clinical feature of RDEB, but fetal complications of chronic constipation are rarely reported. To the author's best knowledge, it has not been reported or recognized in the English literature previously. [ncbi.nlm.nih.gov]

    It's very important for a person who has had the pull-through surgery to avoid constipation. Constipation can lead to enterocolitis or infections of the intestine that can be life threatening. [cedars-sinai.edu]

    Constipation Constipation is defined as small, hard, difficult, or infrequent stools. [my.clevelandclinic.org]

    […] affects bladder control Constipation can cause accidential leakage from your bladder. [continence.org.au]

    A few kids might continue to have symptoms, including constipation and bowel control problems. [kidshealth.org]

  • Abdominal Pain

    These cases presented with abdominal pain. Some patients complained of right lower quadrant pain and other with diffuse abdominal pain of few days duration. [bmcresnotes.biomedcentral.com]

    The most common clinical manifestations of colonic disease in AIDS are diarrhea, lower gastrointestinal bleeding, and abdominal pain. [ncbi.nlm.nih.gov]

    Abdominal pain can be crampy, achy or sharp, and can be intermittent or constant. Abdominal pain related to colon disease may come and go in waves and may be accompanied by bloating. [livestrong.com]

  • Chronic Diarrhea

    Evaluation of chronic diarrhea. Am Fam Physician. 2011;84:1119-1126. Crohn’s and Colitis Foundation of America. Types of Crohn’s disease and associated symptoms. [crohnsdisease.com]

    Colonoscopy performed for chronic diarrhea in an HIV-infected child Rectal Polyp Rectal Polyp Rectal Polyp Rectal Polyp Foreign Body Foreign Body Foreign Body Foreign Body Removal with snare Juvenile Polyp Stalk Juvenile Polyp Stalk Juvenile Polyp Juvenile [naspghan.org]

    Potassium — Increased risk with chronic vomiting and diarrhea, prednisone use. Reviewed by health care specialists at UCSF Medical Center. [ucsfhealth.org]

    Clinically patients have chronic diarrhea (sometimes bloody) associated with tenesmus, pain and fever 1. C-reactive protein levels are usually normal 6. [radiopaedia.org]

    diarrhea for 3 years associated with significant weight loss. [acgcasereports.gi.org]

Skin

  • Flushing

    This process includes taking laxatives, teas, powders or supplements, using enemas, or getting colonic irrigation (colon hydrotherapy) to flush out the colon. There can be side effects to cleansing, and some practices can even be dangerous. [livescience.com]

Psychiatrical

  • Fear

    But a 2008 Harvard study put these fears to rest. [health.harvard.edu]

Workup

Colon capsule endoscopy is feasible to perform after incomplete colonoscopy and guides further workup in clinical practice. Gastrointest Endosc 2014;79:307-16. [ Crossref ] [ PubMed ] Pioche M, de Leusse A, Filoche B, et al. [atm.amegroups.com]

X-Ray

  • Pneumoperitoneum

    This is a quick and readily available investigation that will demonstrate signs of obstruction or pneumoperitoneum, and direct subsequent investigation and intervention. [clevelandclinicmeded.com]

Treatment

Treatment will be continued for a period of 8 weeks. Treatment success will be defined as a complete response to therapy at the end of eight weeks. [clinicaltrials.gov]

Asymptomatic diverticulosis requires no treatment. When symptoms develop, treatment varies depending on clinical manifestations. [merckmanuals.com]

Treatment With regard to treatment, before contemplating replacement therapy with hormone supplements or chemical mediators (thyroid hormones, oestrogens, progesterone, anti- depressants, calcium therapy, which are the usual treatments for this type of [hydrotomiepercutanee.com]

Medical condition: Patients with histologically confirmed metastatic colorectal cancer progressed after a first line treatment containing FOLFIRI and BEV. [clinicaltrialsregister.eu]

Treatment may involve diet, medicines and in some cases, surgery. NIH: National Institute of Diabetes and Digestive and Kidney Diseases [medlineplus.gov]

Prognosis

Treatment and prognosis Total colectomy is curative of both the intestinal symptoms and of the potential risk of colorectal carcinoma. [radiopaedia.org]

The course and prognosis of ulcerative colitis. Part IV. Carcinoma of the colon. Gut 1964;5:15–22. Google Scholar 12. Broomé U, Lindberg G, Löfberg R. [link.springer.com]

The prognosis for acute severe colitis depends on their initial response to corticosteroid treatment. [patient.info]

A cancer's stage will determine the treatment options and inform the prognosis, or the likely course the cancer will take. [medicalnewstoday.com]

Etiology

[…] significantly more frequent in the cirrhotic patients (92%) than in the control group (64%); however, such lesions did not seem specific to the disease and were not statistically correlated with the degree of esophageal varices by Child's grading, the etiology [ncbi.nlm.nih.gov]

The etiology of colonic diverticulosis is multifactorial and not entirely known. [merckmanuals.com]

In cases of complicated diverticular disease, where a colonic fistula is present, a colonoscopy can confirm the site and etiology of the fistula. [clevelandclinicmeded.com]

Epidemiology

Factors affecting colectomy rate in ulcerative colitis: an epidemiological study. Gut 1990;31:329–33. PubMed Google Scholar 19. Schroeder KW, Tremaine WJ, Ilstrup DM. [link.springer.com]

Transmural granulomatous disease affecting GI tract from esophagus to anus but discontinuous ( Wikipedia, eMedicine #1, #2 ) Terminology Also called regional enteritis because it affects sharply delineated segments, or granulomatous colitis due to granulomas Epidemiology [pathologyoutlines.com]

Back to Top Incidence and Epidemiology The incidence of diverticulosis in the Western world has progressively increased over the past century. [clevelandclinicmeded.com]

Epidemiology [ 1 ] Ulcerative colitis is the most common type of inflammatory disease of the bowel. It has an incidence in the UK of approximately 10 per 100,000 people annually and a prevalence of approximately 240 per 100,000. [patient.info]

Pathophysiology

Pathophysiology and theoretic considerations are mentioned where applicable and current therapy is discussed. The conditions are classified under infectious, neoplastic, iatrogenic, and congenital. [ncbi.nlm.nih.gov]

Thus, our data indicate differences in IEL populations between CD, UC, and controls, which support the pathophysiologic differences between CD and UC. The different phenotypes suggest a role for these cells in the diagnosis of IBD. [jimmunol.org]

Epidemiology and pathophysiology of diverticular disease. Clin Colon Rectal Surg 2018; 31(4):209–213. Aldoori WH, Giovannucci EL, Rimm EB, Wing AL, Trichopoulos DV, Willett WC. [clevelandclinicmeded.com]

The pathophysiology of diverticular bleeding is unknown, but several mechanisms are hypothesized, including Local trauma from impacted feces in a diverticulum that can erode the adjacent vessel Enlargement of the diverticulum that can stretch (and ultimately [merckmanuals.com]

Prevention

Lifestyle interventions in the prevention and treatment of cancer, American Journal of Lifestyle, septembre 2009, vol. 3, no 5, 337-48. [passeportsante.net]

BACKGROUND & AIMS: Colonic mucins secreted by goblet cells protect the colon by preventing the attachment of enteric pathogens to the epithelium. [ncbi.nlm.nih.gov]

Maintaining a healthy diet can help prevent the development of colonic polyps. This includes eating more fruits, vegetables, whole grains, and lean meat. You may also be able to prevent polyps by increasing your intake of vitamin D and calcium. [healthline.com]

Summary Many diseases of the colon and rectum can be prevented or treated by seeking prompt medical care. Most importantly, colon cancer is a preventable disease. The most important risk factor is having a direct family member who had colon cancer. [my.clevelandclinic.org]

A normal fiber diet is advisable to prevent constipation and perhaps prevent the formation of more diverticula. [medicinenet.com]

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