genetic, non-syndromic cerebral malformation due to abnormal neuronal migration disease characterized by the association of cortical dysplasia and pontocerebellar hypoplasia, manifesting with global developmental delay, mild to severe intellectual disability [malacards.org]

In addition, we report 1 individual with macrocephaly and intellectual disability without seizures. [ng.neurology.org]

Abnormal cortical development is increasingly recognized as a cause of developmental disabilities and epilepsy. [karger.com]

Present with – Epilepsy / learning disability. MRI: Lobar / gyral hypoplasia, atrophy of underlying white matter blurring of gray- white border. Increased T2 & decreased T1 signal intensity. 15. [slideshare.net]

Brain 129: 352– 365 Google Scholar Shepherd CW, Stephenson JBP (1992) Seizures and intellectual disability associated with tuberous sclerosis complex in the west of Scotland. [link.springer.com]

distress, and dysphagia, early-onset, mild variant 614399 612453 Autosomal recessive METTL23 17q25.1 Mental retardation, autosomal recessive 44 615942 615262 Autosomal recessive MFN2 1p36.22 Charcot-Marie-Tooth disease, axonal, type 2A2A 609260 608507 [mnglabs.com]

Seizures from the cingulate gyrus can involve screaming, aggressive behavior, and feelings of intense fear. The heart and breathing rate may rise, and sweating and pallor can also occur. [childneurologyfoundation.org]

 Early hypotonia, later spastic quadriplegia and opisthotonus. 8. Subcortical band heterotopia-Double cortex Sub-cortical, symmetric, circumferential bands of gray matter, separated from cortex by thin band of white matter. [slideshare.net]