Axial post-gadolinium fat saturated T1w image (C) shows heterogeneous enhancement of the posterior soft tissue mass. No normal orbital contents such as extraocular muscles or globe can be identified in the anterior portions of the orbit. [bmcophthalmol.biomedcentral.com]

Systemic associations [ 8 ] include saddle nose, facial clefting, nostril malformation, choanal atresia, malformation of the sphenoid bone and other neurological abnormalities. [bmcophthalmol.biomedcentral.com]

Babies with mild microcephaly often don’t have problems other than small head size. A baby with severe microcephaly has a head that’s much smaller than expected and may have more serious health problems than a baby with mild microcephaly. [marchofdimes.org]

No structures like cornea, lens, retinal pigmented epithelium or rosettes were identified. [ncbi.nlm.nih.gov]

A mass of glial tissue filled the vitreous cavity, and there was extensive fibrous and osseous metaplasia of the retinal pigment epithelium. In both globes, the retina was totally detached ( Figure 2a ). [nature.com]

Optic pits along the rim of the optic disc are most likely to lead to serous detachments of the retina, with associated full-thickness or laminar retinal holes, retinal pigment epithelium mottling and general cystic changes. [aao.org]

• This configuration is accompanied by situs inversus of the retinal vessels, congenital inferonasal conus, thinning of the inferonasal retinal pigment epithelium and choroid, and myopic astigmatism. • These features presumably result from a generalized [slideshare.net]

Clinical findings include language and speech disorders, truncal ataxia, ocular movement disorders, cognitive impairment, and behavioral disorders. The prognosis and outcome depend mostly on the presence and extent of supratentorial lesions. [pubs.rsna.org]