Atypical presentations of viral infections can be a diagnostic challenge in the newborn period. [ncbi.nlm.nih.gov]

• Fishing

  Molecular diagnosis could only be established using interphase fluorescence in situ hybridization (FISH) analysis which may be considered as a valuable additional diagnostic tool in similar cases. [ncbi.nlm.nih.gov]

• Failure to Thrive

  Caput succedaneum Craniotabes Crying - excessive (0-6 months) Failure to thrive Hemorrhagic disease of the newborn Home apnea monitor use - infants Hyperglycemia - infants Hyperviscosity - newborn Hypocalcemia - infants Intussusception (children) Irritability [icdlist.com]

  […] to Thrive (FTT) Sleeping, behavior, sensory issues Seizures Death (in rare cases) Babies born with congenital CMV can appear to be either symptomatic or asymptomatic at birth. [nationalcmv.org]

  […] to thrive, intracerebral calcifications, microcephaly, hypotonia, seizures, petechial rash, hearing loss, interstitial pneumonitis, thrombocytopenia, anemia, hepatitis, chorioretinitis, or CMV in cerebrospinal fluid Intraventricular hemorrhage [ Time [clinicaltrials.gov]

• Hepatomegaly

  Possible signs and symptoms include: jaundice / hepatomegaly / splenomegaly microcephaly sensorineural deafness chorioretinitis petechiae mental retardation seizures The degree of neurological impairment is variable, from mild learning and behavioral [radiopaedia.org]

  KEYWORDS: biliary atresia; cholestatic hepatitis; congenital cytomegalovirus; hepatitis; hepatomegaly; idiopathic neonatal hepatitis [ncbi.nlm.nih.gov]

  Hepatomegaly occurred from day 56 onward. [doi.org]

  Patients with generalized congenital CMV infection most commonly present with hepatomegaly, splenomegaly, microcephaly, jaundice and petechiae. 49 Thirty percent of patients with severe disease die of multiorgan dysfunction. 50 Hepatomegaly and splenomegaly [academic.oup.com]

  Their clinical symptoms include jaundice, thrombocytopenia, hepatomegaly, petechiae, purpura, and splenomegaly. [elsevier.es]

• Hearing Impairment

  They were divided into five age-matched groups: normal-hearing control, asymptomatic cCMV, normal-hearing symptomatic cCMV, hearing-impaired symptomatic cCMV, and hearing-impaired Cx26. [ncbi.nlm.nih.gov]

• Spastic Quadriplegia

  Children in this series were mostly born at term (n 8), with symptoms or signs of cCMV (n 10) and had spastic quadriplegia (n 9), epilepsy (n 8), intellectual deficit (n 12), communication (n 10) and hearing impairments (n 9). [ncbi.nlm.nih.gov]

• Quadriplegia

  Children in this series were mostly born at term (n 8), with symptoms or signs of cCMV (n 10) and had spastic quadriplegia (n 9), epilepsy (n 8), intellectual deficit (n 12), communication (n 10) and hearing impairments (n 9). [ncbi.nlm.nih.gov]

The workup for maternal infection and fetal structural anomaly was negative except for positive CMV Ige in the maternal serum Cesarean section was performed due to fetal distress. [ncbi.nlm.nih.gov]

The workup for congenital CMV infection was performed in all newborns and stillbirths but not for induced abortion. [cid.oxfordjournals.org]

A longitudinal diagnostic workup should be started with a CMV PCR of leukocyte and plasma specimens to detect the period of DNAemia. [doi.org]

After treatment, CMV DNA decreased in copy number and became undetectable. No marked side effects occurred after treatment. Surprisingly, 1 year after treatment, neurological and motor development was equivalent to that in a healthy infant. [ncbi.nlm.nih.gov]

The prognosis of individuals with CMV is highly variable, and the prognosis of individuals with congenital CMV can usually be determined based on the extent of infection at birth. [ncbi.nlm.nih.gov]

Etiologic investigations revealed a positive polymerase chain reaction for cytomegalovirus DNA using her stored Guthrie card, indicating a congenital cytomegalovirus infection. [ncbi.nlm.nih.gov]

KEYWORDS: Cytomegalovirus; epidemiology; paediatrics [ncbi.nlm.nih.gov]

In this book the history of this disease, its pathophysiological background, epidemiology and symptoms, as well as diagnostic and therapeutic strategies, will be discussed. [libreriauniversitaria.it]

Intrauterine hemodynamics may be important in pathophysiology of congenital cytomegalovirus infection. [ncbi.nlm.nih.gov]

In this book the history of this disease, its pathophysiological background, epidemiology and symptoms, as well as diagnostic and therapeutic strategies, will be discussed. [libreriauniversitaria.it]

Advances in the treatment and prevention of congenital CMV infection are a high priority nationally and globally. [ncbi.nlm.nih.gov]