Edit concept Question Editor Create issue ticket

Congenital Digital Clubbing


  • A rationalisation of the 1350 boxes used throughout the book gives a simpler and clearer presentation of the various categories.[books.google.com]
  • The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.[orpha.net]
  • We are presenting two cases (brother and sister) with digital clubbing in all the four limbs. Systemic examination and laboratory investigation were normal.[atharvapub.net]
  • Most other diagnosis books on the market are either “physical diagnosis” texts targeting student readers or “differential diagnosis” books intended for use by practicing physicians, though both types of books aim to be comprehensive.[books.google.ro]
  • New ‘In Adolescence’ boxes recognise the fact that many chronic disorders begin in childhood and become the responsibility of physicians practising adult medicine.[books.google.com]
  • Physicians have long attempted to diagnose diseases depicted in paintings, 8 and this focus is a growing field of interest, 9 but apparently no physician has published an article about this particular piece.[pediatrics.aappublications.org]
  • Am Fam Physician. 2001 Jul 1;64(1):141-142. A 31-year-old woman with a 10-year history of chronic renal insufficiency secondary to bilateral obstructive hydronephrosis presented for evaluation of pain in the right hip.[aafp.org]
  • There are two new chapters on examination in specific situations: The frail elderly The adult with fever A new section explicitly spells out how to demonstrate the techniques learned in the book in an OSCE and other formative and summative examinations[books.google.com]
  • Related Cases Disease: Nail Diseases Finger Injuries and Disorders Tuberculosis Symptom/Presentation: Cough Fever and Fever of Unknown Origin Respiratory Distress Specialty: Emergency Medicine Infectious Diseases Preventive Medicine and Health Maintenance[pediatriceducation.org]
  • Chun Wai Chan Case A Malay man, aged 23 years, presented to his local general practitioner (GP) with a 1-week history of fever, sore throat and mild bilateral shoulder, elbow and knee pain without joint effusion.[racgp.org.au]
  • This inflammation occurs with a fever and joint pain or a large amount of fluid in the synovial area of a joint. Certain vascular conditions may additionally appear, along with bluish skin discoloration and sweating.[news-medical.net]
  • R68.12 Fussy infant (baby) R68.13 Apparent life threatening event in infant (ALTE) R68.19 Other nonspecific symptoms peculiar to infancy R68.2 Dry mouth, unspecified R68.3 Clubbing of fingers R68.8 Other general symptoms and signs R68.83 Chills (without fever[icd10data.com]
Congenital Digital Clubbing
  • Clinical description Isolated congenital digital clubbing is often painless and usually symmetrical and bilateral. Sometimes, some fingers or toes are spared, but the thumbs are almost always involved.[orpha.net]
  • Familial Congenital Digital Clubbing - Report of Two Siblings. Indian Journal of Child Health , 1 (1), 19-21. Retrieved from[atharvapub.net]
  • 26 thanks, 21 comments 02 Aug 2016 Thank Share Post Verified response Appears to be isolated congenital digital clubbing, usually symmetrical and bilateral.[dailyrounds.org]
  • Acronym ICNC Synonyms Clubbing of digits Hereditary acropachy Isolated congenital digital clubbing Any medical or genetic information present in this entry is provided for research, educational and informational purposes only.[uniprot.org]
  • […] amyloidosis, Arctic type Hereditary cerebral hemorrhage with amyloidosis, Dutch type Hereditary cerebral hemorrhage with amyloidosis, Flemish type Hereditary cerebral hemorrhage with amyloidosis, Iowa type Hereditary cerebral hemorrhage with amyloidosis, Italian[csbg.cnb.csic.es]
  • Acquired from a private collection by the Italian State in 2011, the painting was completed shortly after 1620 by Giovanni Lanfranco, one of the masters of the Italian Baroque. 1 This brief article describes the painting and explores its importance for[pediatrics.aappublications.org]
  • […] disease of nails, Diseases of nail NOS, Nail disease NOS (disorder), Nail disorder, Nail disease, disease (or disorder); nails, nail; disorder, Disease of nail, NOS, Disorder of nail, Disease of nail (disorder), Disorder of nail (disorder), Nail Diseases Italian[fpnotebook.com]
Nail Abnormality
  • Text Reference: "Nail Abnormalities: Clues to Systemic Disease." American Family Physician.[emedicinehealth.com]
  • Nail abnormalities: clues to systemic disease. Am Fam Physician . 2004 Mar 15. 69(6):1417-24. [Medline] . Sridhar KS, Lobo CF, Altman RD. Digital clubbing and lung cancer. Chest . 1998 Dec. 114(6):1535-7. [Medline] .[emedicine.medscape.com]
Respiratory Disorders
  • Get comprehensive, authoritative coverage on today's hot topics, such as interstitial lung disease, respiratory disorders in the newborn, congenital lung disease, swine flu, genetic testing for disease and the human genome, inflammatory cytokines in the[books.google.ro]
Koplik Spot
  • -Pathognomonic signs allowing an occasional early diagnosis: For example, Koplik spots in a febrile child are found only with measles.[books.google.ro]
Bone Pain
  • -Clinical manifestations that may point to uncommon diagnoses: For example, nocturnal bone pain, sometimes dramatically relieved by aspirin, characterizes osteoid osteoma.[books.google.ro]
  • Other patients may present with fractures, bone pain, cranial nerve palsies and osteomyelitis. 2 Heberden's nodes are osteophytes of the distal interphalangeal joint, typically seen in osteoarthritis.[aafp.org]
  • If there are no findings on the history or physical examination, the next step is to identify whether the patient has a family history of HOA (positive symptoms for arthralgia and/or bone pain) or clubbing. Table 1.[racgp.org.au]
Back Pain
  • -Plastic pearls exposed: For example, contrary to clinical lore, back pain at night has not been found to be a useful indicator for serious spinal pathology.[books.google.ro]
  • Pain Low Back Pain, Disabling Low Back Pain, Lumbar Spinal Stenosis Lumbar Puncture Malaria Malnourishment, Adult Medical Decision-Making Capacity Melanoma Meningitis, Adult Menopause Migraine Mononucleosis Murmur, Diastolic Murmur, Systolic Myasthenia[jamaevidence.mhmedical.com]
  • A new chapter specifically on Stroke Disease recognises the emergence of Stroke Medicine as a distinct clinical and academic discipline.[books.google.ro]
  • Severe Alcohol Withdrawal Syndrome Sexual Abuse, Child Shoulder Instability Sinusitis Sleep Apnea Splenomegaly Streptococcal Pharyngitis Stroke Stroke, Hemorrhagic Temporal Arteritis Thoracic Aortic Dissection Upper Gastrointestinal Bleed Urinary Incontinence[jamaevidence.mhmedical.com]
  • This is usually a symmetric and painless condition; however, cases of unilateral clubbing (brachial arteriovenous fistula and hemiplegic stroke) and painful clubbing (hypertrophic osteoarthropathy) can occur.[thebigl.co]
  • This showed that clubbing developed in all digits studied and that it increased with the duration of the stroke. Clubbing did not correlate with the grip strength of the weakened hand. 1975 S.[karger.com]
  • Kalamangalam First published May 7, 2012, DOI: A 64-year-old man was evaluated for seizures due to traumatic brain injury 25 years previously.[neurology.org]
  • Underlying conditions associated with bronchiectasis include primary ciliary dyskinesia, Kartagener syndrome, cystic fibrosis, and diffuse panbronchiolitis. [6] Lung abscess Risk factors include immunosuppression, poor oral hygiene, drug abuse, alcoholism, seizure[online.epocrates.com]


  • Significance of Digital Clubbing Clubbing is a clinical sign which may indicate and prompt the workup for an underlying disease. It is often seen in pulmonary conditions. However, clubbing is also seen in some people without any underlying disease.[medcaretips.com]
  • Since clubbing usually presents with an underlying disease, it is important to perform a comprehensive workup and to treat the underlying pathology before taking any further steps.[the-dermatologist.com]
  • .  Medico legal PitfallsMedico legal Pitfalls  Failure to perform a thorough and exhaustiveFailure to perform a thorough and exhaustive workup of the patient who presents withworkup of the patient who presents with clubbing of the nails since clubbing[slideshare.net]


  • With advances in diagnosis and treatment in children, more and more of those with CHD survive well into adulthood.[books.google.com]
  • Stay at the forefront of your field with updated treatment methods throughout, as well as an increased focus on patients with skin of color.[books.google.ro]
  • The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.[orpha.net]
  • Your recommended treatment plan will depend on your diagnosis.[healthline.com]
  • What is the treatment for hypertrophic osteoarthropathy and clubbing? The main aim of treatment for secondary hypertrophic osteoarthropathy is treatment of the underlying malignancy or chronic disease.[dermnetnz.org]


  • Prognosis Clubbing is potentially reversible if the underlying condition is treated early enough but the changes may be irreversible once collagen deposition has set in.[patient.info]
  • Prognosis of the underlying disease should be determined on an individual basis. Goyal S, Griffiths AD, Omarouayache S, Mohammedi R. An improved method of studying fingernail morphometry: application to the early detection of fingernail clubbing.[emedicine.medscape.com]
  • A review of cardiac and non-cardiac malformations in 60 cases withspecial reference to diagnosis and prognosis. Br Heart J. 1975 August; 37(8): 840–852. Marton T, Cesko I, Hajdu J et al.[learn.pediatrics.ubc.ca]


  • Etiology It results from proliferation of the connective tissues between the nail matrix and the distal phalanx and abnormal function of the nail matrix.[orpha.net]
  • Etiology of clubbing in most of the time is secondary to some systemic illness. Familial clubbing is a rare occurrence and incidence or prevalence of such occurrence is not known.[atharvapub.net]
  • etiology? 26 thanks, 21 comments 02 Aug 2016 Thank Share Post Verified response Appears to be isolated congenital digital clubbing, usually symmetrical and bilateral.[dailyrounds.org]
  • CLUBBING/DIGITAL CLUBBING Etiologies Digital clubbing is a physical finding characterized by an enlargement of the distal segment of the fingers or toes, which may or may not be associated with underlying disease states.[thebigl.co]
  • The specific etiology is not known; however, in adults many cases are due to pulmonary disease and resultant hypoxia, and some other cases are due to heart disease, liver disorders, or disorders of the gastrointestinal tract.[medical-dictionary.thefreedictionary.com]


  • Summary Epidemiology Prevalence is unknown. Clinical description Isolated congenital digital clubbing is often painless and usually symmetrical and bilateral. Sometimes, some fingers or toes are spared, but the thumbs are almost always involved.[orpha.net]
  • […] nail clubbing Classification (Orphanet): - Rare bone disease - Rare developmental defect during embryogenesis - Rare genetic disease - Rare skin disease Classification (ICD10): - Congenital malformations, deformations and chromosomal abnormalities - Epidemiological[csbg.cnb.csic.es]
  • Presents revisions by a new authorship of experts in infectious disease, genetics and epidemiology, sports medicine, neurology, cardiac surgery, cardiac anesthesiology, and more.[books.google.com]
  • Epidemiology Pachydermoperiostosis is rare and is characterised by skin thickening of the forehead, eyelids and hands, digital clubbing and periostosis. [ 2 ] The epidemiology of secondary clubbing depends on the cause.[patient.info]
  • El-Domyati,Hossam Abdel-Wahab,Eman Abdel-Azim Journal of Cosmetic Dermatology. 2014; 13(4): 269 3 Geriatría y dermatología: revisión de la literatura Cristián Navarrete-Dechent,María Constanza del Puerto Troncoso,Ariel Hasson Nisis Piel. 2013; 28(3): 154 4 Epidemiological[ijdvl.com]
Sex distribution
Age distribution


  • Pathophysiology Advances in the study of the pathogenesis have established that vascular endothelial growth factor (VEGF) is key.[bestpractice.bmj.com]
  • Clubbing is thought to result from changes to the volume of interstitial fluid and increased blood flow to the area but the exact pathophysiology remains unknown. Primary clubbing may be idiopathic or be a feature of an inherited condition.[patient.info]
  • Pathophysiology The exact cause for sporadic clubbing is unknown, and there are numerous theories as to its cause.[chdbabies.com]
  • Pathophysiology of Clubbing Clubbing is characterized by an increase in the pulp tissue due to proliferation of subungual connective tissue, interstitial edema and dilation of arterioles and capillaries.[epomedicine.com]
  • The exact pathophysiological mechanism for each cause of clubbing is unknown but an increase in vascular endothelial growth factor appears to be an important common pathway.[pediatriceducation.org]


  • Can clubbing be prevented? The only way to prevent clubbing is by taking steps to prevent and manage the underlying conditions that cause it.[healthline.com]
  • The results also suggest that existing drugs such as aspirin, which are already used to prevent PGE2 production, may be effective in reducing the painful symptoms of finger clubbing.[sciencedaily.com]
  • Health care services aimed at preventing health problems or maintaining health are provided. Medical Knowledge 10. An investigatory and analytic thinking approach to the clinical situation is demonstrated. 11.[pediatriceducation.org]
  • […] oil and the like Drops of Tea tree oil on the nail beds as well as use of essential oils Salt water treatment for 5 minutes on the nail beds Consumption of green leafy vegetables on a regular basis No cutting of cuticles Overall, nail clubbing can be prevented[healtreatcure.org]
  • Author Robert A Schwartz, MD, MPH Professor and Head of Dermatology, Professor of Pathology, Pediatrics, Medicine, and Preventive Medicine and Community Health, Rutgers New Jersey Medical School; Visiting Professor, Rutgers University School of Public[emedicine.medscape.com]

Ask Question

5000 Characters left Format the text using: # Heading, **bold**, _italic_. HTML code is not allowed.
By publishing this question you agree to the TOS and Privacy policy.
• Use a precise title for your question.
• Ask a specific question and provide age, sex, symptoms, type and duration of treatment.
• Respect your own and other people's privacy, never post full names or contact information.
• Inappropriate questions will be deleted.
• In urgent cases contact a physician, visit a hospital or call an emergency service!