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Congenital Epulis

Congenital Gingival Cell Tumor


Presentation

  • We present the case of a female newborn, otherwise healthy, presenting with a giant swelling protruding from her mouth and originating from upper left alveolar ridge.[ncbi.nlm.nih.gov]
  • This article presents a case report of a female infant who presented a fibrotic mass in the primary lateral incisor and canine region of the maxillary alveolar ridge. The lesion was not causing feeding or respiratory problems.[ncbi.nlm.nih.gov]
  • We present five cases: four cases presented as single pedunculated nodules of the gingiva and in one case two nodules were present. Of all, 50% were located at the maxilla.[ncbi.nlm.nih.gov]
  • The case presented here is the prenatal diagnosis of a congenital epulis discovered in the 32nd week of pregnancy.[ncbi.nlm.nih.gov]
  • A female newborn with multiple congenital epulis on the mandibular alveolar ridge and tongue is presented, and her preferred treatment and histopathological diagnosis are discussed.[ncbi.nlm.nih.gov]
Vietnamese
  • A 2.7-kg 364-g male infant was born after uncomplicated normal spontaneous vaginal delivery to a 34-year-old gravida 2 para 2 Vietnamese woman.[jamanetwork.com]
Soft Tissue Swelling
  • Indian J Pathol Microbiol 2009;52:436-7 A full-term normally delivered female child was referred to the department of pediatric surgery immediately after birth for a protruding, sessile soft tissue swelling from her mouth.[ijpmonline.org]
Prolonged Bleeding
  • Suture was necessary due to the prolonged bleeding time. Post-operative instructions were given to the mother's baby. After 1 week, the suture was removed and oral tissues presented normal post-surgical healing.[jisppd.com]
Respiratory Disorders
  • The newborn showed no respiratory disorder. There were no other clinically visible malformations. A peripheral vein was taken for an infusion of hypertonic glucose solution 10% to fight against possible hypoglycaemia.[panafrican-med-journal.com]
Respiratory Insufficiency
  • In utero, obstruction of the oral cavity can result in ineffective swallowing and can cause polyhydramnios. [6] Postnatally, clinical manifestations depend on the size and location of the lesions and include respiratory insufficiency, difficulty in sucking[jcnonweb.com]
Failure to Thrive
  • Diagnosis and prompt intervention can prevent expected complications such as failure to thrive or respiratory difficulty.[ncbi.nlm.nih.gov]
Cyanosis
  • Some other common clinical manifestations include dyspnea, cyanosis, cough, difficulty in sucking and swallowing and occasionally, vomiting.[ 15 ] Perinatal MRI of the oral cavity helps in differentiating congenital epulis from other masses of oral cavity[ncbi.nlm.nih.gov]
Suggestibility
  • It is suggested that the natural history of the congenital epulis is one of regression, and no treatment is required unless the lesion causes feeding or respiratory problems.[ncbi.nlm.nih.gov]
  • Two previous ultrasound studies performed at 21 and 28 weeks' gestation showed normal facial anatomy, suggesting accelerated tumour growth during the third trimester. Genetic amniocentesis also showed the infant to possess a 47, XXX karyotype.[ncbi.nlm.nih.gov]
  • We report a 2-day-old female with tumor mass on the anterior mandibular alveolar ridge, which demonstrated immunoreactivity for vimentin, S-100 and neuron-specific enolase; thus, suggesting a similar histogenesis with granular cell tumor.[ncbi.nlm.nih.gov]
  • Immunohistochemical studies revealed intense staining for vimentin, STRO-1, and CD44, suggesting that it was derived from mesenchymal cells. The literature and immunohistochemical profile of congenital epulis are also discussed.[ncbi.nlm.nih.gov]
  • These results suggest that the congenital epulis may be derived from uncommitted nerve-related mesenchymal cells.[ncbi.nlm.nih.gov]
Agitation
  • Simple conservative surgical excision at the tumor base should be done to allay the parent agitation. Wide radical excision is not recommended.[jcnonweb.com]
Amenorrhea
  • It was after a full-term pregnancy (37 weeks of amenorrhea), during which, no related-pregnancy pathology nor unrelated ones was discovered. There was no concept of taking foetal toxic drug by the mother.[panafrican-med-journal.com]

Treatment

  • Treatment of this lesion was surgical, and histopathological examination confirmed the clinical diagnosis of congenital epulis.[ncbi.nlm.nih.gov]
  • Surgical treatment in this milieu may be simple and complete at the time of delivery.[ncbi.nlm.nih.gov]
  • Although it has not been yet clarified the etiology of this tumor and the role of hormonal influences on its appearance and development and despite have been reported cases of spontaneous regression, the treatment of choice is the early surgical excision[ncbi.nlm.nih.gov]
  • The theories of pathogenesis, the surgical treatment, the histologic appearance, and a 5-year follow-up are described. As with previous cases reported, there has been no recurrence.[ncbi.nlm.nih.gov]
  • The diagnosis, pathology, and treatment are reviewed.[ncbi.nlm.nih.gov]

Prognosis

  • They have an excellent prognosis, if treated properly. This paper will discuss our experience with these 2 lesions and review the literature.[ncbi.nlm.nih.gov]
  • […] delayed or wrong, exposing so the newborn parents to useless days of waiting and anxiety In our opinion all pediatricians and surgeons should be aware of this malformation and of its simple, safe and effective surgical treatment, considering the excellent prognosis[ncbi.nlm.nih.gov]
  • Significantly revised and updated content throughout this edition brings you the latest information on the etiology, clinical features, histopathology, treatment, and prognosis of each disease entity, as well as cutting-edge topics such as bisphosphonate[books.google.ro]
  • The prognosis is excellent with very rare recurrence [3]. :: References Figures [Figure - 1][jpgmonline.com]

Etiology

  • The etiology and histogenesis of the lesion remain obscure. This lesion can pose a risk of airway obstruction or can interfere with feeding. The report presented here describes a case of congenital granular cell lesion in the left maxillary region.[ncbi.nlm.nih.gov]
  • Careful attention to alternative diagnoses led to the correct etiology. Primary care pediatricians encounter neonatal oral lesions infrequently. The most common oral lesions in the newborn period are Epstein pearls and Bohn nodules.[ncbi.nlm.nih.gov]
  • The authors discuss the clinical picture, histological findings, etiology and treatment of this rare lesion.[ncbi.nlm.nih.gov]
  • Although it has not been yet clarified the etiology of this tumor and the role of hormonal influences on its appearance and development and despite have been reported cases of spontaneous regression, the treatment of choice is the early surgical excision[ncbi.nlm.nih.gov]
  • Significantly revised and updated content throughout this edition brings you the latest information on the etiology, clinical features, histopathology, treatment, and prognosis of each disease entity, as well as cutting-edge topics such as bisphosphonate[books.google.ro]

Epidemiology

  • […] common in patients with congenital epulis due to swallowing difficulties as a result of the size of the growth, but the mother did not attend antenatal clinics and gave birth at home. [5] CENB is very similar to GCT histologically, but differs from it epidemiologically[ijdr.in]
  • These epidemiological data show the rarity of this benign neoplasm, the most frequently diagnosed at birth with a female-male ratio of 8:1 9,10.[zdoc.site]
  • The aim of this study was to analyze the epidemiological, clinical and histological aspects of epulis of the newborn, by means of presentation of a clinical case report.[revodonto.bvsalud.org]
  • An atypical case of congenital epulis such as the one being reported also demonstrates that it is essential to keep in mind the clinical, radiographic and histological characteristics of the lesion and not just the epidemiological characteristics to establish[ijcasereportsandimages.com]
Sex distribution
Age distribution

Prevention

  • This paper describes the case of a day old baby who was admitted to hospital because of the presence of a large intraoral swelling that was preventing her from breast feeding.[ncbi.nlm.nih.gov]
  • Diagnosis and prompt intervention can prevent expected complications such as failure to thrive or respiratory difficulty.[ncbi.nlm.nih.gov]
  • In our case, the tumor size was six centimeters and obstructing the oral cavity and preventing breast feeding.[panafrican-med-journal.com]

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