Presentation
Individual case presentations provide a valuable tool for differential diagnosis. [books.google.com]
Presentation : these variably present from early childhood (especially lymphangiomas) to adulthood. Varices present with intermittent proptosis (evident in the Valsalva manoeuvre) visible lesions in the eyelid. [patient.info]
Snapshot A 27-year-old woman with vitiligo presents to her primary care physician with progressive fatigue and weight loss despite a good appetite. [medbullets.com]
More than 95% of children born to mothers with Graves disease present with symptoms within the first month of life; rarely, presentation is delayed into the second month. [merckmanuals.com]
Respiratoric
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Pleural Effusion
effusion 350 Pleural effusion with or without pulmonary pathology 351 Parietal pleural thickening without pleural fluid 352 Localized pleural thickening in children 353 The Mediastinum and the Diaphragm Mediastinum 1 Pneumomediastinum in infancy and [books.google.com]
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Respiratory Distress
distress in the newborn 272 Lung disease in the newborn 275 Wetlung disease 276 The airbronchogram pattern in the newborn 277 White lung appearance in the newborn 278 Pulmonary hemorrhage A complication of 279 Bilateral homogenous opacification in neonates [books.google.com]
Fetus
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Hydrops Fetalis
Stay at the forefront of your field thanks to new and completely revised chapters covering topics such as: Principles and Practice l Immune and Non-immune Hydrops Fetalis l Amniotic Fluid Volume l Enhancing Safe Prescribing in the Neonatal Intensive Care [books.google.com]
Eyes
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Bilateral Proptosis
In children, bilateral proptosis may be caused by metastatic neuroblastoma, leukemic infiltrates, TED, or NSOI. [aao.org]
Causes of bilateral proptosis include: 1. Developmental anomalies of the skull: craniofacial dysostosis e.g., oxycephaly (tower skull). 2. Osteopathies: Osteitis deformans, rickets and acromegaly. 3. [ikeyes.blogspot.com]
Etiology / Causes of Proptosis: Inflammatory/Infection: Graves’ ophthalmopathy, due to Graves’ disease (Thyroid Eye Disease), usually causes bilateral proptosis. Orbital cellulitis – Infection of the orbit. [oculoplastic-eyelid-orbit-surgery.com]
Another tumour affecting the orbit and so resulting in proptosis is granulocytic sarcoma (chloroma) which may present with rapid onset of (occasionally bilateral) proptosis at about 7 years of age. [patient.info]
This might explain why one autoantibody to the TSHr can cause disease in both the thyroid and the eyes Lid Retraction Proptosis Graves Disease Grave's Ophthalmolopathy is the most common caused of unilateral or bilateral proptosis in adults. [eyeplastics.com]
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Strabismus
Research of Exophthalmos Congenital has been linked to Exophthalmos, Orbital Neoplasms, Neoplasms, Teratoma, Strabismus. [novusbio.com]
Strabismus — Any deviation of the eyes from a common direction. Commonly called a turned eye. [medical-dictionary.thefreedictionary.com]
Abnormal Eyeball Positioning If your kitten’s eyeball appears abnormally positioned, he may have strabismus, exophthalmos or enophthalmos. Strabismus occurs when one or both eyes look off in different directions, often referred to as crossed eyes. [pets.thenest.com]
Lagophthalmos (eyelid cannot close) Orbital Fracture(s) Orbital Tumors Ptosis Revisional Eyelid Surgery Stye (Chalazion) Optometry & Low Vision Pediatric Ophthalmology & Eye Alignment Disorders Accommodative Esotropia Amblyopia Eye Movement Disorders Strabismus [health.ucsd.edu]
Practical Ophthalmology 58 2000 Chiasmal syndrome New J Mustrated Hand book of Clinical Ophthalmology 8 1999 Intranuclear ophthalmoplegia Practical Ophthalmology 43 1999 Nystogmus Practical Ophthalmology 1997 Research Grants & Projects Plain Text Study on strabismus [researchmap.jp]
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Unilateral Proptosis
It presents with acute, usually unilateral proptosis with severe pain. [oculoplastic-eyelid-orbit-surgery.com]
Causes of unilateral proptosis include: 1. Congenital conditions. These include: dermoid cyst, congenital cystic eyeball, and orbital teratoma. 2. Traumatic lesions. [ikeyes.blogspot.com]
Unilateral proptosis in adults is also most frequently caused by TED. In children, bilateral proptosis may be caused by metastatic neuroblastoma, leukemic infiltrates, TED, or NSOI. [aao.org]
Workup
X-Ray
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Bowel Distention
distention 484 Malabsorption patterns of the small bowel 486 Fixed stiff small bowel loops 487 Destruction of the small bowel mucosa 488 Deformation of the terminal ileum 489 Lesions mimikig regional enteritis 490 Abnormalities of the ileocecal valve [books.google.com]
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Atelectasis
[…] chest in the newborn 283 Unilateral hyperlucent thorax in the newborn 284 Coarse parenchymal markings with irregular bilateral changes and hyperinflation in the newborn 285 Cystlike structures in the lung parenchyma of the newborn 286 Neonatal platlet atelectasis [books.google.com]
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Hyperlucent Lungs
lung 313 Bilateral underaeration of the lungs in the pediatric age 315 Pneumonia pattern in children 316 Acute alveolar disease 317 Lobar pneumonia in children 318 Homogeneous lobar or segmental opacification 319 Round pneumonia 320 Pulmonary round lesions [books.google.com]
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Colonic Stricture
stricture or narrowing 496 Segmental colonic narrowing in children 497 Toxic megacolon 498 Distention of the small andor large bowelnonobstructive paralytic ileus 499 Distended large bowel 500 Large bowel obstruction 502 Large retrorectal space 503 Large [books.google.com]
Colonoscopy
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Colitis
[…] mucosa 488 Deformation of the terminal ileum 489 Lesions mimikig regional enteritis 490 Abnormalities of the ileocecal valve 491 Large bowel 73 Cecal filling defects or deformed cecum 492 Typhlitis 493 Filling defects in the colon Single or multiple 494 Colitis [books.google.com]
Pleura
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Pleural Effusion
effusion 350 Pleural effusion with or without pulmonary pathology 351 Parietal pleural thickening without pleural fluid 352 Localized pleural thickening in children 353 The Mediastinum and the Diaphragm Mediastinum 1 Pneumomediastinum in infancy and [books.google.com]
Treatment
Features coverage of the latest treatment innovations including antibiotic residue testing, care of individual metabolic disease, troubleshooting, and much more. [books.google.com]
Treatment If a tumor is growing behind the eye, it needs to be removed. If Graves' disease is the cause, it may subside with treatment of the overactive thyroid, but this is not guaranteed. [medical-dictionary.thefreedictionary.com]
& Medications Thyrogen Treatment – Thyroid Cancer Thyrogen FAQs Nexavar Treatment – Thyroid Cancer Radioactive Iodine – To Treat the Thyroid Gland Surgery – Hemi Thyroidectomy – Total Thyroidectomy Hyperthyroidism/OveractiveThyroid Hypothyroidism/Underactive [thyroidfoundation.org.au]
Birthmarks are very common and most types do not require any treatment at all. [gosh.nhs.uk]
Prognosis
Prognosis Exophthalmos can be progressive. Its progress must be carefully followed, treating complications as they occur. Prevention Vision can usually be preserved with attentive treatment. [medical-dictionary.thefreedictionary.com]
Surgical outcomes with 360-degree suture trabeculotomy in poor-prognosis primary congenital glaucoma and glaucoma associated with congenital anomalies or cataract surgery. [freethesaurus.com]
Prognosis of ocular myasthenia. Ann Neurol 1983 Nov;14(5):516-9. 17. Weinberg DA, Lesser RL, Vollmer TL. Ocular myasthenia: a protean disorder. Surv Ophthalmol 1994 Nov-Dec;39(3):169-210. 18. Kanski JJ. Clinical Ophthalmology, 4th ed. [reviewofoptometry.com]
Etiology
[…] interstitial and granulonodulo alveolar pattern 324 Interstitialreticular pulmonary pattern 326 Disseminated interstitial pneumonitis 327 The miliary pattern of pneumonia 328 Short linear andor wedgeshaped densities 329 Pulmonary edema in infancy and childhood Etiology [books.google.com]
Otorhinolaryngological examination is necessary when the paranasal sinus or a nasopharyngeal mass apears to be a possible etiological factor. II. [ikeyes.blogspot.com]
[…] thyroid enlargement myxedema dermal accumulation of mucopolysaccharides non-pitting hyperreflexia Studies Diagnostic testing diagnostic approach screening for patients with clinical suspicion autoantibody titers are diagnostic imaging to differentiate etiologies [medbullets.com]
Etiology / Causes of Proptosis: Inflammatory/Infection: Graves’ ophthalmopathy, due to Graves’ disease (Thyroid Eye Disease), usually causes bilateral proptosis. Orbital cellulitis – Infection of the orbit. [oculoplastic-eyelid-orbit-surgery.com]
The etiology of the thyroid-related orbitopathy is an autoimmune process, predominantly affecting the fat and the extraocular muscles. There is accompanying accumulation of glycosaminoglycans and water. [clinipedia.wordpress.com]
Epidemiology
Epidemiology and prevention of Graves' ophthalmopathy. Thyroid. 2002 Oct. 12(10):855-60. [Medline]. Putta-Manohar S, Perros P. Epidemiology of Graves' orbitopathy. Pediatr Endocrinol Rev. 2010 Mar. 7 Suppl 2:182-5. [Medline]. [emedicine.medscape.com]
Introduction Clinical definition autoimmune hyperthyroidism Epidemiology demographics the most common cause of hyperthyroidism in the United States female dominant typically 20-40 years of age Pathogenesis triggered by stress e.g. childbirth, infection [medbullets.com]
The epidemiologic characteristics and clinical course of ophthalmopathy associated with autoimmune thyroid disease in Olmsted County, Minnesota. Trans Am Ophthalmol Soc 1994;92:477-588. 8. Brazis PW, Lee AG. Binocular vertical diplopia. [reviewofoptometry.com]
Pathophysiology
PATHOPHYSIOLOGY OF EXOPHTHALMOS There is a small amount of redundant space within the orbit and so any swelling within these tissues results in forward displacement of the globe. [clinipedia.wordpress.com]
The pathophysiology of thyroid eye disease: implications for immunotherapy. Curr Opin Ophthalmol. 2011 Sep. 22 (5):385-90. [Medline]. Ugradar S, Rootman DB. Case Series: Noninflammatory Thyroid Eye Disease. [emedicine.medscape.com]
Decreased vision - visual acuity may be impaired by: Direct optic nerve involvement due to the pathophysiology. Distortion of the macula by a lesion pushing in behind the globe. Exposure keratopathy (see above) can also affect the visual acuity. [patient.info]
Prevention
Revised drug usage recommendations and legal considerations present the most current information in these critical areas to help you prevent dangerous or costly errors. [books.google.com]
Prevention Vision can usually be preserved with attentive treatment. There is currently no way to prevent any of the underlying conditions that lead to exophthalmos. Resources Books Fauci, Anthony S., et al., editors. [medical-dictionary.thefreedictionary.com]
Early detection and treatment could prevent vision loss. See an eye care professional right away if you have a sudden change in vision, if everything looks dim, or if you see flashes of light. [icdlist.com]
Hyperthyroidism can cause exophthalmos How can it be prevented? In some cases, in its initial stages, exophthalmos can only be detected using imaging techniques. [imo.es]
Medicine and medications: Ocular lubricants: Keep adequate moisture in eye and prevent dryness.Artificial tears (Celluvisc, Murine, Refresh, Tears Naturale). [medigoo.com]