Presentation
Growth and developmental delays are frequently present in microphthalmia that is caused by a chromosomal disorder. [msdmanuals.com]
Each child in the BOSU data set was assigned one of four outcomes, three in which the child's identifiers matched those in the NCAS data set, and one when no match was present ( Table 1 ). [nature.com]
[…] never a single isolated malformation, but is usually a part of a complex syndrome associating ethmocephaly and arrhinencephaly, in varying degrees ANOPHTHALMIA refers to the uni- or bilateral absence of the eyes The eyelids and motor muscles usually are present [discovery.lifemapsc.com]
This can be present at birth, or it can develop later. If a hemangioma begins pressing on a nerve or if there is a carotid artery dissection (a splitting of the artery that feeds the brain), Horner's syndrome can develop. [chw.org]
Entire Body System
- Juvenile Cataract
Page updated June 2018 *Congenital and juvenile cataracts. Ophthalmology, 3rd ed. 2008. **Pediatric cataracts. Textbook of Family Practice, 7th ed. 2007. [allaboutvision.com]
Eyes
Skin
- Anhidrosis
The nerve dysfunction can cause ptosis (droopy eyelid), miosis (small pupil when compared to the other), and anhidrosis (lack of sweating) on one side of the face. This can be present at birth, or it can develop later. [chw.org]
Treatment
Treatment focuses on maximizing visual potential with glasses and patching. Patients are treated by ophthalmic surgeons, as necessary, for treatment of glaucoma, cataracts, or other associated anomalies. [sciencepublishinggroup.com]
The best treatment is prevention for certain eye problems. [chw.org]
What is included in treatment of congenital/developmental eye anomalies? Treatment focuses on maximizing visual potential with glasses and patching. [childrensnational.org]
Most infants with ROP improve spontaneously, but some develop severe changes that require treatment with a laser. [dmei.org]
Prognosis
Prognosis Prognosis is good, particularly in the absence of glaucoma. The documents contained in this web site are presented for information purposes only. [orpha.net]
Identification of the underlying syndrome is important for prognosis and family counseling; a clinical geneticist, when available, can help guide the evaluation. Click here for Patient Education NOTE: This is the Professional Version. [merckmanuals.com]
Parents will be made aware of the visual potential of the child, the possible need for special educational placement, and the long-term prognosis and/or progression of the disease. In some cases low vision aids may be necessary or helpful. [childrensnational.org]
Diffuse interstitial pulmonary fibrosis.[10] Prognosis The mortality can be as high as 60%. [patient.info]
Etiology
[…] agents MICROPHTHALMIA: the eyeball and the lens are small and more or less malformed This malformation frequently is associated with coloboma This condition can be produced experimentally by the use of the same substances listed under B (3) above The etiology [discovery.lifemapsc.com]
Cases without a known genetic or syndromic etiology were primarily investigated to determine phenotypic and inheritance patterns. [jamanetwork.com]
Although the etiology of this disease is not fully understood, autosomal recessive or dominant inheritance is possible. The disease occurs as sporadic cases. Male:female ratio for the Goldenhar's syndrome is 2:1. [academic.oup.com]
Etiology Patients with ARS have been found to have mutations in the transcription factor genes PITX2 (4q25) and FOXC1 (6p25). A large number of different mutations have been identified but there is no clear genotype-phenotype relationship. [orpha.net]
Poland- Möbius syndrome and cocaine abuse: a relook at vascular etiology. Pediatr Neurol. 2005; 32(4):285-7. [ Links ] Ghabrial R, Versace P, Kourt G, Lipson A, Martin F. Möbius syndrome: features and etiology. [scielo.br]
Epidemiology
This problem motivated one of the authors to establish a new model of disaster epidemiology. [books.google.com]
The data also serve to inform service planning and medical/epidemiological research. [nature.com]
Rahi From the Departments of Paediatric Epidemiology and Ophthalmology, Institute of Child Health/Great Ormond Street Hospital National Health Service Trust; and the Department of Epidemiology, Institute of Ophthalmology, London, United Kingdom. [iovs.arvojournals.org]
Abstract There is little information about the epidemiology of congenital eye anomalies in Ghana. [apps.who.int]
Pathophysiology
The progression of keratoglobus is unpredictable, mainly because of our limited understanding of the pathophysiology of the condition. Keratoglobus is associated with impaired vision, but not blindness. [lecturio.com]
Prevention of aspiration remains the most important aim and there appears to be consensus around the world that preventative measures should be used more.[2, 3] Pathophysiology[2] If aspirated material is sufficiently acid (pH lower than 2.5) and there [patient.info]
Prevention
The best treatment is prevention for certain eye problems. [chw.org]
Some birth defects can be prevented. Taking folic acid can help prevent some birth defects. Talk to your doctor about any medicines you take. Some medicines can cause serious birth defects. [icdlist.com]
Prevention of aspiration remains the most important aim and there appears to be consensus around the world that preventative measures should be used more.[2, 3] Pathophysiology[2] If aspirated material is sufficiently acid (pH lower than 2.5) and there [patient.info]
Interventions to prevent aspiration pneumonia in older adults: a systematic review. J Am Geriatr Soc. 2003 Jul. 51(7):1018-22. [Medline]. Logemann JA, Gensler G, Robbins J, et al. [medscape.com]
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