Symptoma

Congenital Onychodysplasia

COIF

[…] normal number of fingers or toes, is presented. megalodactyly. // Taber's Cyclopedic Medical Dictionary (2009);2009, Issue 21, p1429 A definition of the term "megalodactyly," which refers to having very large fingers or toes is, presented. megalosyndactyly [connection.ebscohost.com]

We report a case of a COIF presenting as a congenital bifid nail deformity with underlying bone deformity. [ncbi.nlm.nih.gov]

Ectodermal dysplasia’s is usually associated with hair, palmoplantar involvement and dental abnormalities which are not present in our case. [2] The present case has been reported for the rarity of the condition, newborn presentation, associated features [ijpd.in]

  • Nail Abnormality

    Various nail abnormalities are observed, including (1) anonychia (lack of a fingernail), (2) micronychia (a small fingernail deviated to 1 side of the nail bed), (3) polyonychia (multiple, small, individual nails on one nail bed), (4) hemionychogryphosis [dermaamin.com]

    The nail abnormalities are recognized at birth and include micronychia or anonychia, especially on the thumbs. The lunula can be triangular or V-shaped and this finding may be pathognomonic for the condition. [handresearch.com]

    Nail Abnormalities Lucas and Opitz108 have reviewed the literature. Although abnormalities involving the nail are generally present at birth, two separate reports describe postnatal nail changes. Fingers are usually affected. [sites.google.com]

    Various nail abnormalities result in pain or interference with functioning or both. Nail disorder may affect walking, picking up of fine objects and protective function. [odermatol.com]

  • Turkish

    Turkish Journal of Pediatrics 56(4): 462-463, 2016 Congenital nail defects or onychodysplasia of the index fingers report of a case and a review of previously reported cases in japan. [eurekamag.com]

  • Pathologist

    Edited by four leading surgical pathologists - Noel Weidner, MD, Richard J. Cote, MD, Saul Suster, MD and Lawrence M. [books.google.com]

  • Multiple Congenital Anomalies

    congenital anomalies Kallmann syndrome in a patient with congenital spherocytosis and an interstitial 8p11.2 deletion Novel mutation in the nephrin gene of a Japanese patient with congenital nephrotic syndrome of the Finnish type Panostotic fibrous dysplasia [documents.mx]

  • Systolic Murmur

    Echocardiogra-phy performed because of a systolic murmur demon-strated a tiny patent foramen ovale and a moderate ven-triculoseptal defect. [docslide.com.br]

  • Short Hands

    In addition to the typical bilateral split nail of the second finger, the patient showed bilateral inguinal hernia, a peculiar face, and short hands. [ncbi.nlm.nih.gov]

    This syndrome has beenfound mainly in Japan, and as far as weknow, this is the first case reported in Italy.In addition to the typical bilateral split nailof the second finger, the patient showedbilateral inguinal hernia, a peculiar face,and short hands [documents.tips]

  • Generalized Tonic-Clonic Seizure

    Atnine years and 11 months, he had a generalized tonic-clonic seizure without fever. EEG showed a left frontalfocus and treatment with anticonvulsants was startedthereon. Neuropsychiatric evaluation showed moderatemental retardation. [documents.tips]

Treatment - Isolated congenital nail dysplasia There is no known treatment for ICND. Symptomatic treatment helps alleviate the disease burden. Resources - Isolated congenital nail dysplasia [checkorphan.org]

Statistics and Research Methods Stem Cell Transplantation Substance Use and Addiction Surgery Surgical Innovation Surgical Pearls Teachable Moment Technology and Finance The Rational Clinical Examination Tobacco and e-Cigarettes Toxicology Trauma and Injury Treatment [doi.org]

It istherefore possible that bone growth will continue and thedefect will appear later as narrowing of the distal pha-lanx, as has been extensively described.The third baby is the first case of COIF associatedwith gestational diabetes and insulin treatment [docslide.com.br]

Persons finding themselves or loved ones under medical treatment because of Congenital onychodysplasia of the index fingers may like to share how they cope in order to help others world-wide searching for experiences. [bordeglobal.com]

Prognosis - Isolated congenital nail dysplasia The ICND is a lifelong condition. Patient documented by Pavone (1982) lost his nails almost completely in his twenties and did not regain them before he died at 77. [checkorphan.org]

Nail changes are not only seen in extensive alopecia areata but may also be present with minimal hair loss and does not imply a poor prognosis for regrowth. Uniform pitting is the most common abnormality seen in alopecia areata. [odermatol.com]

The etiology of this condition is unknown, but clinical study suggested that ischemia of the finger at a certain period of embryonic life might play an important part in its pathogenesis. [ncbi.nlm.nih.gov]

Classification of these conditions often presents many nosological challenges, since underlying etiologies and pathogenetics are often not known. [howlingpixel.com]

Radiological examination of affected fingers; Bifurcation of the affected distal phalanx of the big toe; Etiology of the disease. [connection.ebscohost.com]

Miscellaneous etiologies A report from 2014 suggests that hepatitis B may have played a role in the development of congenital onychodysplasia of the index fingers. [9] The role of infection is unclear but warrants further consideration. [emedicine.medscape.com]

Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10coded.com]

Haeneke E: Epidemiology and Pathology of onychomycosis. In Onychomycosis Nolting S. Korting Eds. Berlin Springer Verlay 1989; 1-8. 6. Williams HC: The epidemiology of onychomycosis in Britain. Br J Dermatol. 1993; 26: 481-490. 7. [odermatol.com]

Brenner/Rector remains the go-to resource for practicing and training nephrologists and internists who wish to master basic science, pathophysiology, and clinical best practices. [books.google.com]

A genetic mechanism most likely underlies the pathophysiology of congenital onychodystrophy of the index finger (COIF). [5, 6]. Most cases are sporadic, but autosomal dominant transmission has been described. [emedicine.medscape.com]

[…] index fingernails Deformities of the nails on other fingers Radiographic abnormalities of the distal bony phalanx on the affected fingers Congenital occurrence, which can be either hereditary or sporadic A genetic mechanism most likely underlies the pathophysiology [dermaamin.com]

Prevention - Isolated congenital nail dysplasia Not available. Genetic counselling may help in families where the disease occurred previously. [checkorphan.org]

Transplantation Substance Use and Addiction Surgery Surgical Innovation Surgical Pearls Teachable Moment Technology and Finance The Rational Clinical Examination Tobacco and e-Cigarettes Toxicology Trauma and Injury Treatment Adherence United States Preventive [doi.org]

Centers for Disease Control and Prevention Intersex (Medical Encyclopedia) [ Read More ] [icdlist.com]

This acellular membrane is tightly adherent and prevents invasive microorganisms reaching the underlying matrix. The lunula (half moon) represents the distal portion of the nail’s proliferative matrix. [clinicalgate.com]