Due to corneal anesthesia, it usually presents with recurrent, painless eye infections, painless corneal opacities and/or poorly healing, ulcerated wounds on the facial skin and mucosa (typically the buccal mucosa and/or nasal septum).[orpha.net]
A 2-month-old infant presented with bilateral corneal erosions and complete corneal anesthesia. Her sister presented at age 3 years with a corneal ulcer and corneal hypoesthesia (sensation markedly decreased).[ncbi.nlm.nih.gov]
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Due to corneal anesthesia, it usually presents with recurrent, painless eye infections, painless cornealopacities and/or poorly healing, ulcerated wounds on the facial skin and mucosa (typically the buccal mucosa and/or nasal septum).[orpha.net]
Karger AG, Basel Case Report A 16-month-old boy was referred to the Yamaguchi University Hospital on 10 December 2009 because of untreatable cornealopacity.[karger.com]
Her older sister initially required antibiotic ointment for her corneal ulcer but now requires only ocular lubrication for congenital trigeminal anesthesia.[ncbi.nlm.nih.gov]
Due to corneal anesthesia, it usually presents with recurrent, painless eye infections, painless corneal opacities and/or poorly healing, ulcerated wounds on the facial skin and mucosa (typically the buccal mucosa and/or nasal septum).[orpha.net]
Initially this was investigated as an infected ulcer and treated for several weeks as herpetic ulceration with no beneficial effect.[insights.ovid.com]
Given that malignancy is a prominent feature of recently diagnosed preganglionic Horner syndrome, patients may avoid an unnecessary extensive workup for carcinoma if the lesion can be shown to be old or long-standing.[emedicine.medscape.com]
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The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.[orpha.net]
[…] aqueductal stenosis sutural synostosis other supratentorial abnormalities 8 hypoplasia of the commissural system ( corpus callosum, anterior commissure ) hypoplasia of the anterior visual pathway agenesis of the posterior lobe of the pituitary Treatment and prognosis[radiopaedia.org]
An accurate and up-to-date classification is important for therapy, prognosis, and genetic counseling of the affected children and their families.[austinpublishinggroup.com]
Prognosis Several undesirable side effects may follow the procedure. The first is that the numbness may have an unpleasant or painful sensation. Often the numbness has an undesirable quality; similar to the way it feels after a Novocain injection.[ufhealth.org]
[…] posterior communicating artery aneurysm ) Pupillary sparing often due to ischemic microangiopathy Treatment Compressive lesions: surgery Ischemic microangiopathy or demyelinating lesions: medical management with adequate control of the underlying disease Prognosis[amboss.com]
The estimated frequency of the numb chin syndrome in breast cancer is approximately 4% and is usually associated with a poor prognosis [ 46 ].[neupsykey.com]
Etiology Clinical features Extorsion of the eye : inability to depress and adduct the eyeball simultaneously (the pupil shoots upward during attempted adduction of the eyeball) Diplopia ( double vision ) Mild esotropia Trigeminal nerve lesion (V) Etiology[amboss.com]
TN is classified as symptomatic when the etiology is known and as idiopathic when the etiology is unknown.[ncbi.nlm.nih.gov]
Another common etiology of neurotrophic keratopathy is diabetes mellitus. Diabetes either may be the primary cause of neurotrophic keratopathy or secondarily may predispose patients to this condition.[aao.org]
Epidemiologic features of chronic atrial fibrillation: the Framingham study. N Engl J Med 1982; 306 : 1018–1022. 15. Roark S F, McCarthy E A, Lee K L, Pritchett E L C.[nature.com]
A spectrum of pathophysiological processes may affect the trigeminal nerves, including traumatic, vascular, inflammatory, demyelinating, infectious, and neoplastic disorders.[oasisdiscussions.ca]
Pathophysiology The cornea has a high density of nerve endings from the long posterior ciliary nerves and is 100 times more sensitive than the conjunctiva.[aao.org]
With multiple etiologies causing corneal anesthesia, the cellular pathophysiological mechanisms are complex and not yet fully investigated [ 4 ].[journals.plos.org]
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Anesthesia: Goals are to provide brain relaxation for good surgical exposure and to maintain adequate CPP (at least 70 mmHg) to prevent cerebral ischemia from brain retraction.[anesthesia.ucsf.edu]
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