Presentation
Table 2 Summary of ocular and naevus findings of all naevi at presentation and of those 59 cases followed up at MEH. [nature.com]
The occurrence of iris naevus in our present study population was substantially higher. [ncbi.nlm.nih.gov]
Diagnosis Patients usually present for an eye examination when they recognize a new lesion or growth of a preexisting lesion. [eyewiki.aao.org]
Skin
- Freckles
The presence of iris freckles and iris naevi was also documented. [ncbi.nlm.nih.gov]
Treatment
Treatment with topical mitomycin or interferon alpha 2b can be considered for histology-proven PAM with atypia including residual lesions - but only for lesions confined to the epithelium as these local treatment strategies are not proper for melanomas [eyewiki.aao.org]
Boston ocular surface prosthesis for persistent epitheliopathy after treatment of conjunctival melanoma. Cornea., 29 (2010), pp. 459-461 [21.] A.D. Paridaens, D.C. Minasssian, A.C. Cartney, et al. [elsevier.es]
Frequent misdiagnosis of amelanotic naevi can lead to unnecessary anti-inflammatory treatment (scleritis, episcleritis, pinqueculitis are the most important differential-diagnostic pathologies). [ncbi.nlm.nih.gov]
Prognosis
Prognosis Nevi are congenital lesions and only a small percentage progress into malignant melanoma. PAM with atypia has a high likelihood to progess into malignant melanoma in contrast to PAM without atypia. [eyewiki.aao.org]
Prevention
MMC can be added after surgery to help prevent a recurrence although there are severe side effects that must be discussed with the patient. [eyewiki.aao.org]
Considering the high potential of conjunctival melanoma for developing metastatic disease, early detection or even primary prevention of the tumour development is of great importance [3, 4, 5]. [ncbi.nlm.nih.gov]