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Corneal Blood Staining


  • This case report presents the diagnosis and management of a rare case of traumatic GCG after vitreous hemorrhage in a phakic child. Pars plana vitrectomy was done after unsuccessful medical therapy and the diagnosis was confirmed by cytopathology.[ncbi.nlm.nih.gov]
  • However, there was still CBS present, and a mature cataract was noted (Figure 1). Surgery was delayed, and the patient was monitored monthly.[millennialeye.com]
  • […] to offer three-year Family Medicine Accelerated Track 20% Practicing physicians in West Texas are TTUHSC graduates Programs at a Glance The M.D.[ttuhsc.edu]
  • Quickly reference information with help from a convenient outline format, ideal for today’s busy physician.[books.google.com]
  • Both of these conditions require attention by a physician or ophthalmologist, but are treatable.[wounds1.com]
  • Am Fam Physician. 2004;70(1):124. Figure 1. Anatomy of the cornea. Reprinted with permission from Wilson SA, Last A. Management of corneal abrasions. Am Fam Physician. 2004;70(1):124.[aafp.org]
  • Many physicians avoid these agents, as we did with our patient.[glaucomatoday.com]
Surgical Procedure
  • Mostly single case reports show that it occurred after cataract surgery, corneal grafting, traumatic hyphema, corneal ulcers, chemical burns and viscocanalostomy. [1], [2] Canaloplasty is a recent non-penetrating glaucoma surgical procedure, similar to[ijo.in]
  • The surgical procedure is subject to the availability of corneal tissue for grafting, and it requires an additional lens.[retinalphysician.com]
  • Corneal hematoma is a rare complication and has been reported after different surgical procedures like cataract surgery, is associated with Moorens ulcer, spontaneously and after canaloplasty in Glaucoma. [1, 2, 3, 4 ] Deep corneal hematoma after penetrating[djo.org.in]
  • The investigators felt that, relative to other surgical procedures, trabeculectomy can keep the IOP low while the remaining blood clears from the anterior chamber. 9 Because our patient did not have preexisting glaucoma and his IOP was elevated for only[glaucomatoday.com]
Vascular Disease
  • While unconventional, it seemed more acceptable to lay the book out under the relatively limited and broad headings which ophthalmologists use as indications for enucleation: "trauma", "tumour", "endophthalmitis", "vascular disease", etc.[books.google.com]
  • If only neurological stuff just Harada syndrome) Term Definition local inflammation of the episcleral vessels. differentiate from conjunctival injection by using phenyl. may be idiopathic or related to TB, syphilis, RA or other collagen vascular diseases[flashcardmachine.com]
Rubeosis Iridis
  • Spontaneous hyphemas occur without inciting trauma and are usually caused by the abnormal growth of blood vessels, vascular anomalies, uveitis, tumors of the eye, rubeosis iridis, hemophilia, leukemia and other conditions or medications that cause thinning[flei.com]
  • May also occur spontaneously, without any inciting trauma, and are usually caused by neovascularization, tumors of the eye (retinoblastoma or iris melanoma), uveitis, or vascular anomalies. rubeosis iridis, myotonic dystrophy, leukemia, hemophilia, von[standardofcare.com]
  • These include ophthalmic surgery, rubeosis iridis (abnormal blood vessel growth in the iris), vitreous hemorrhage (the presence of blood in the gel fluid behind the eye), blood dyscrasias (when the ingredients of the blood are irregular, such as in hemophilia[wounds1.com]
  • iridis, myotonic dystrophy, leukemia, hemophilia, and von Willebrand disease. [1] Conditions or medications that cause thinning of the blood, such as aspirin, warfarin, or drinking alcohol may also cause hyphema.[en.wikipedia.org]
Visual Impairment
  • A 54-year-old man with a history of severe proliferative diabetic retinopathy in both eyes and profound visual impairment presented with severe corneal blood staining in the left eye secondary to a "spontaneous" total hyphaema and raised intraocular pressure[ncbi.nlm.nih.gov]
  • Hyphemas require urgent evaluation as they may result in permanent visual impairment. May result in hemosiderosis and heterochromia, elevation of the intraocular pressure for up to 6 days. Most resolve within 5–6 days.[standardofcare.com]
  • impairment. [ citation needed ] A long-standing hyphema may result in hemosiderosis and heterochromia.[en.wikipedia.org]
  • Those in or near the centre of the cornea increase risk of visual impairment.[patient.info]
  • Once the amount of hemoglobin overwhelms the keratocytes’ capacity to metabolize it, they undergo necrosis. 5 This observed cell death might be due to photosensitivity, as McDonnell et al found that hematoporphyrin derivatives accumulate in the cells,[millennialeye.com]
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  • Systemic workup first. Calcium can usually be removed from Bowman's by chelation with EDTA, need to remove epithelium. Gentle surface. itation may help. EDTA nor scraping will remove accompanying fibrous tissue. Tx can be repeated if needed.[quizlet.com]
Ophthalmic Test Finding
  • View anatomic details, common ophthalmic test findings, and examples of classic histopathology specimens through brand-new illustrations and photographs.[books.google.com]


  • Autologous blood injection is an accepted form of treatment for hypotony that occurs secondary to overfiltration; however, injection into the filtering bleb has been associated with a rise in intraocular pressure for some patients with chronic postoperative[ncbi.nlm.nih.gov]
  • Recent dramatic advances in diagnosis, as well as medical and surgical treatment, mean that you can offer your glaucoma patients more timely and effective interventions.[books.google.de]
  • Be fully prepared for current exam topics with information on the latest techniques in corneal surgery, macular degeneration treatment and trials, and expanded treatment options for many sections.[books.google.com]
  • These are potent oxidizing agents that cross-link the plasma membrane, causing cell damage. 6 Although more studies on prevention and management of CBS are needed, this and previous studies show that aggressive treatment of increased IOP, evacuation of[millennialeye.com]


  • Prognosis: Cases of corneal blood staining secondary to hyphema have cleared spontaneously. One case cleared after 2 years without known intraocular pressure elevation. Many cases will have opacified corneas that require penetrating keratoplasty.[missionforvisionusa.org]
  • […] risk of rebleeding by inhibiting the conversion of plasminogen to plasmin, and thereby keeping clots stable. [2] However, the evidence for their effectiveness is limited and amioncaproic acid may actually cause hyphemas to take longer to clear. [4] Prognosis[en.wikipedia.org]
  • "Generally speaking, though, the prognosis is pretty good." Dr. Ahmed prefers a "very conservative" management strategy in general, with an emphasis on treating hyphema medically rather than surgically.[eyeworld.org]
  • […] while hsv is epi defect) and thygeson superficial punctate keratophaty "after chemical injury with limbal stem cell destruction, when should you wait to perform stem cell transplant" logner the better because inflammation can lead to cell death and poor prognosis[freezingblue.com]
  • PKP prognosis is poor due to chronic ocular surface disease. Do alkali or acids cause worse chemical burns? What are signs of an unfavorable visual prognosis with alkali burns? Extensive limbal epithelial damage and intraocular chemical penetration.[quizlet.com]


  • DISCUSSION Etiology of endothelial damage, seen consistently in CBS, remains unclear. Messmer et al found extracellular hemoglobin concentrated in the posterior stroma, whereas intracellular hemosiderin predominated anteriorly.[millennialeye.com]
  • Etiology: A combination of hyphema and resultant elevated intraocular pressure are believed to be important in the pathogenesis of blood stained corneas.[missionforvisionusa.org]
  • While formulating treatment plans, physicians should remember that the elevated IOP may be due to multiple concomitant etiologies and adjust their strategy accordingly.[glaucomatoday.com]
  • […] keratitis, asymptomatic infiltrates, CLARE, contact lens-induced peripheral ulcer, infiltrative keratitis or microbial keratitis. 16 There are many variant presentations of corneal infiltrates that can be solely inflammatory or may have an infectious etiology[reviewofcontactlenses.com]


  • On average, the increased pressure in the eye remains for six days before dropping. [3] Most uncomplicated hyphemas resolve within 5–6 days. [3] Epidemiology [ edit ] As of 2012, the rate of hyphemas in the United States are about 20 cases per 100,000[en.wikipedia.org]
  • The epidemiology of ocular injury in a major US automobile corporation. Eye (Lond). 1998;12(pt 5):870–874. 3. Wilson SA, Last A. Management of corneal abrasions. Am Fam Physician. 2004;70(1):123–128. 4. Fraser S. Corneal abrasion.[aafp.org]
Sex distribution
Age distribution


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  • He was prescribed prednisolone 1% hourly to prevent rebleeding and atropine 1% twice a day for pain. 4 One week later, the patient’s IOP had increased to 41 mm Hg, and CBS was first noted.[millennialeye.com]
  • Goals of Hyphema treatment Decreasing the risk of re-bleeding within the eye To prevent damage to the optic nerve To prevent corneal blood staining Depending on the severity of the hyphema, treatment may consist of methods to control any increase of intraocular[flei.com]
  • By immobilizing the iris and ciliary body with atropine, additional trauma to the damaged blood vessels in the angle is prevented.[reviewofoptometry.com]

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