Presentation
Apo A-I deficiency may lead to premature atherosclerosis if present in conjunction with additional cardiovascular risk factors. [ncbi.nlm.nih.gov]
Entire Body System
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Fatigue
The most common signs and symptoms of heart failure are shortness of breath or trouble breathing; fatigue; and swelling in the ankles, feet, legs, stomach, and veins in the neck. All of these symptoms are the result of fluid buildup in your body. [web.archive.org]
Other symptoms include shortness of breath and fatigue with activity (exertion). [nlm.nih.gov]
Women are more likely to experience non-traditional symptoms such as: vague chest discomfort fatigue sleep difficulties indigestion anxiety If left untreated, CAD can lead to other serious problems such as heart attack, stroke or even death. [heartandstroke.ca]
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Plethora
Elevated GGT activity level is associated with a plethora of cardio-metabolic risk factors, including traditional cardiovascular risk factors, metabolic syndrome, systemic inflammation, oxidative stress burden and various comorbidities that incur a negative [ncbi.nlm.nih.gov]
Workup
Other tests that may be useful include the following: ECG (including exercise with ECG monitoring and ambulatory ECG monitoring) Selective coronary angiography (the definitive diagnostic test for evaluating the anatomic extent and severity of CAD) See Workup [emedicine.com]
[…] imaging Cardiac computed tomography with CT angiography Electron beam CT scanning (for calculation of coronary artery calcium score) Optical coherence tomography imaging Magnetic resonance imaging Positron emission tomography Coronary angiography See Workup [emedicine.medscape.com]
Other Pathologies
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Myocardial Fibrosis
Aldosterone Receptor Antagonists Aldosterone has been shown to promote myocardial fibrosis. [doi.org]
Treatment
Approximately 50% of the decline was attributable to changes in acute phase and secondary prevention treatments, particularly acute and chronic treatments for heart failure ( 12%), acute coronary syndrome treatments ( 9%) and secondary prevention following [ncbi.nlm.nih.gov]
This may be explained by better monitoring and adherence of drug treatment as five of the six trials were given drug treatment during the study. [doi.org]
Prognosis
It is suggested that this clinical picture has a grave prognosis, demanding urgent therapeutic measures. [ncbi.nlm.nih.gov]
[…] psychosocial risk factors like low socio-economic status, lack of social support, stress at work and family life, depression, anxiety, and hostility contribute both to the risk of developing coronary heart disease (CHD) and the worsening of clinical course and prognosis [doi.org]
Etiology
How to demonstrate C. pneumoniae etiology of CHD We know of no simple ways to prove C. pneumoniae etiology of CHD and have proposed an expensive lengthy observational study supported by laboratory studies. [doi.org]
Angina due to microvascular coronary dysfunction (MCD) is an etiologic mechanism in women with vascular dysfunction. [ncbi.nlm.nih.gov]
Etiologic factors include a genetic susceptibility, because 15% to 20% of patients have a family history of the disorder. AAA is much more common in men than women (2 to 5 times) and more common in white than in black populations. [dx.doi.org]
Epidemiology
Epidemiology Group, Genetics Section, International Agency for Research on Cancer, Lyon, France. [ncbi.nlm.nih.gov]
Pathophysiology
However, it remains unknown whether GGT plays a direct role in the pathophysiology of atherosclerosis and CHD or is merely a correlate of coexisting cardiovascular risk factors. [ncbi.nlm.nih.gov]
Prevention
Secondary prevention of CHD was compared between depression and non-depression groups. [ncbi.nlm.nih.gov]
Follow your provider's directions closely to help prevent CHD from getting worse. [nlm.nih.gov]
They help prevent the digestive tract from absorbing cholesterol. [web.archive.org]