Lipids Lipids are present and located in the envelope. Genome Organization and Replication By itself, genomic nucleic acid is infectious. Transcription: Sub-genomic RNA is present in infected cells. [datamed.org]

SpaceNext50 Britannica presents SpaceNext50, From the race to the Moon to space stewardship, we explore a wide range of subjects that feed our curiosity about space! [britannica.com]

Fred Murphy, Sylvia Whitfield, USCDCP capsid, rubella virus, positive, single cell, SSRNA genome intracellular, group, tumor, virus, particles, present, central, nervous, system ultrastructural, morphology, intact, rotavirus, double, shelled, particles [pixnio.com]

A spreadsheet predicting the inactivation of coronaviruses and the associated uncertainty is presented and can be used to predict virus inactivation for untested temperatures, time points, or any coronavirus strains belonging to Alphacoronavirus and Betacoronavirus [research.pasteur.fr]

REPLICATION CYTOPLASMIC Attachment of the viral S protein (maybe also HE if present) to host receptors mediates endocytosis of the virus into the host cell. [viralzone.expasy.org]

• Falling

  Jonathan Fuller, University of Pittsburgh When people fall seriously ill from the new coronavirus, death rates become a highly personal matter. Yet we talk about them in the most impersonal of ways: with numbers. [msdmanuals.com]

• Inflammation

  Like other coronaviruses, SARS infects the respiratory system, causing damage and inflammation to the lungs. If left unchecked, SARS will eventually cause pneumonia. [study.com]

  Infection by different coronaviruses cause in the host alteration in the transcription and translation patterns, in the cell cycle, the cytoskeleton, apoptosis and coagulation pathways, inflammation, and immune and stress responses. [web.archive.org]

  […] first cytokines induced during inflammation. [doi.org]

• Asymptomatic

  These infections are usually asymptomatic in bats but the mechanism of this tolerance is not yet understood. For those viruses, bats are efficient reservoirs and disseminators. [ncbi.nlm.nih.gov]

  As testing paradigms changed and contacts were increasingly tested, more asymptomatic and mild infections were recognized [ 163 ]. [doi.org]

  Symptoms The clinical spectrum of MERS-CoV infection ranges from no symptoms (asymptomatic) or mild respiratory symptoms to severe acute respiratory disease and death. [who.int]

• Malaise

  Lancet volume 361, 03 May 2003, the authors report that: The most common reported symptom is fever (94%), with 51–72% of patients reporting general influenza-like symptoms, chills, malaise, loss of appetite, and myalgia. [web.archive.org]

• Chills

  Lancet volume 361, 03 May 2003, the authors report that: The most common reported symptom is fever (94%), with 51–72% of patients reporting general influenza-like symptoms, chills, malaise, loss of appetite, and myalgia. [web.archive.org]

• Pneumonia

  6011000124106~MAPPRIORITY~1 6011000124106~MAPRULE~OTHERWISE TRUE 6011000124106~MAPPRIORITY~5 6011000124106~MAPADVICE~IF PNEUMONIA CAUSED BY SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS CHOOSE J12.81 | CONSIDER ADDITIONAL CODE TO IDENTIFY SPECIFIC CONDITION [bioportal.bioontology.org]

  We have isolated a SARS-associated CoV (SARS-CoV) strain by injecting Vero cells with a sputum specimen from an Italian patient affected by a severe pneumonia; the patient traveled from Vietnam to Italy in March 2003. [moh-it.pure.elsevier.com]

  Early transmission dynamics in wuhan, china, of novel coronavirus–infected pneumonia. N Engl J Med. 2020. doi: 10.1056/NEJMoa2001316. Zhu N, Zhang D, Wang W, Li X, Yang B, Song J. A novel coronavirus from patients with pneumonia in China, 2019. [medigraphic.com]

  For many people with MERS, more severe complications followed, such as pneumonia and kidney failure. About 3 to 4 out of every 10 people reported with MERS have died. Most of the people who died had an underlying medical condition. [cdc.gov]

• Dyspnea

  Pleuritis causing dyspnea is observed in some cats, and there are reports of neurologic and ocular disease, occurring in others. Affected cats die within 1 to 8 weeks. [web.archive.org]

• Nausea

  Most people confirmed to have MERS-CoV infection have had severe acute respiratory illness with symptoms of: fever cough shortness of breath Some people also had gastrointestinal symptoms including diarrhea and nausea/vomiting. [cdc.gov]

• Heart Disease

  Kawasaki disease is a childhood illness which mostly affects children under five years old. It is the leading cause of acquired heart disease in children. [web.archive.org]

• Confusion

  The event was created in order to dispel confusion, fear, and anger, related to the Coronavirus panic, and to clarify questions on articles published on the topic on GreenMedInfo.com, and provide resiliency strategies. [greenmedinfo.com]

  /2013/05/outbreak-continues-confusion-reigns-over-virus-patents ] Abdel-Moneim AS. [doi.org]

• Headache

  Coronaviruses - the cause of SARS SARS is a type of viral pneumonia, with symptoms including fever, a dry cough, dyspnea (shortness of breath), headache, and hypoxaemia (low blood oxygen concentration). [web.archive.org]

• Irritability

  Coronaviridae ความหมายคือ โคโรนาวิริเดอี Back to Dictionary (ส่งเข้าทาง inbox facebook) ศัพท์แพทยศาสตร์ (Medical Terminology): คำอื่น ๆ Coronoid Process Corpus Allatum Corpus Luteum Cyst, Ruptured Corpuscles, Calcareous Correlation Charts Corrin Rings Cortex Irritation [dekgenius.com]

• Chlamydia

  […] the 5 new loci from the expanded European Standard Set Enhanced More information Product# EP Product Description 3430 Schmon Parkway Thorold, ON, Canada L2V 4Y6 Phone: 866-667-4362 (905) 227-8848 Fax: (905) 227-1061 Email: [email protected] Chlamydia [businessdocbox.com]

  […] species, Proteus species, Clostridium, Erysipelothrix species, Listeria species, Pasteurella multocida, Streptobacillus species, Spirillum species, Fusospirocheta species, Treponema palladium species, Borrelia species, Actinomycetes, Mycoplasma species, Chlamydia [lens.org]

With this greater understanding of SARS-CoV biology, many researchers have sought to identify agents for the treatment of SARS. [ncbi.nlm.nih.gov]

Treatment There is no specific antiviral treatment recommended for MERS-CoV infection. Individuals with MERS often receive medical care to help relieve symptoms. For severe cases, current treatment includes care to support vital organ functions. [cdc.gov]

This may, therefore, lead to an improper diagnosis of an individual, thereby delaying their treatment. With delayed treatment and the possibility of rapid spread of the disease, the entire kingdom could collapse! [study.com]

Prevention and treatment No vaccine or specific treatment is currently available, however several MERS-CoV specific vaccines and treatments are in development. Treatment is supportive and based on the patient’s clinical condition. [who.int]

Virions are sensitive to treatment with heat, lipid solvents, non-ionic detergents, formaldehyde, and oxidizing agents. Nucleic Acid The genome is not segmented and contains a single molecule of linear positive-sense, single-stranded RNA. [datamed.org]

During the recent severe acute respiratory syndrome (SARS) outbreak, the etiologic agent was identified as a new coronavirus (CoV). [moh-it.pure.elsevier.com]

Abstract During the recent severe acute respiratory (SARS) outbreak, the etiologic agent was identified as a new coronavirus (CoV). [ncbi.nlm.nih.gov]

This picornavirus is the etiological agent of an acute systemic vesicular disease that affects cattle worldwide. [web.archive.org]

[…] of Infectious Bronchitis Virus Molecular Basis of Transmissible Gastroenteritis Virus Epidemiology Pathogenesis of the Porcine Coronaviruses Human Coronavirus Infections The Pathogenesis of Torovirus Infections in Animals and Humans Index Table of Contents [booktopia.com.au]

Over the past several years, I’ve been trying to understand how epidemiological evidence influences thinking in health care. Epidemiological data are critical in deciding public health action, such as when to ease up on social distancing. [msdmanuals.com]

Heparin and SARS-CoV-2: Multiple Pathophysiological Links. Di Micco P, Imbalzano E, Russo V, Attena E, Mandaliti V, Orlando L, Lombardi M, Di Micco G, Camporese G, Annunziata S, Piccinocchi G, Pacelli W, Del Guercio M. Di Micco P, et al. [pubmed.ncbi.nlm.nih.gov]

Prevention Currently, there is no vaccine to prevent MERS-CoV infection. The U.S. National Institutes of Health is exploring the possibility of developing one. [cdc.gov]

Infection prevention and control measures are critical to prevent the possible spread of MERS‐CoV in health‐care facilities. [who.int]

Here we report the utility of the potent antiviral protein griffithsin (GRFT) in the prevention of SARS-CoV infection both in vitro and in vivo. We also show that GRFT specifically binds to the SARS-CoV spike glycoprotein and inhibits viral entry. [ncbi.nlm.nih.gov]

Coronavirus and the common cold Follow this link for comprehensive information on Management, Therapy, and Prevention of the common cold. [web.stanford.edu]