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Cortisone


Presentation

  • After the intake of cortisone and antibiotics he presented duodenum ulcer and bleeding although he had no previous history of gastrointestinal problems.[ncbi.nlm.nih.gov]
  • A discovery, synthesis and therapeutic application of cortisone present a paradigm for modern translational medicine (Hillier 2007, Saenger 2010), since they represented a joint achievement of discoveries by biochemists, Edward Calvin Kendall and Tadeus[ncbi.nlm.nih.gov]
  • She presented to her general practitioner with secondary amenorrhea.[ncbi.nlm.nih.gov]
  • The simple treatment procedure developed in the present study may facilitate simultaneous measurement of more steroids in hair.[ncbi.nlm.nih.gov]
  • We present the 1st case of prepubertal hyperandrogenism because of a defect in the conversion of cortisone (E) to cortisol (F) by hepatic 11beta-hydroxysteroid dehydrogenase type 1. Clinical and anthropometric data were obtained.[ncbi.nlm.nih.gov]
Dutch
  • Ethnicity (Dutch and North European descent) was related to lower levels. High amounts of sun in the month of hair collection was related to higher levels of cortisone only.[ncbi.nlm.nih.gov]

Workup

  • Here, we present a new method, designed for routine laboratory use, which enables quick determination of these analytes with minor sample workup.[ncbi.nlm.nih.gov]
Dyslipidemia
  • F and E levels were similar among patients with unilateral or bilateral adenoma, or considering the presence of hypertension, dyslipidemia, diabetes, or cardiovascular events.[ncbi.nlm.nih.gov]

Treatment

  • Several treatments are available to treat the keloid scar. Keloids have the tendency to recur after surgical removal and new treatments for keloid scars include radiotherapy, cryotherapy or compressive therapy.[ncbi.nlm.nih.gov]
  • An equally effective treatment with fewer adverse side effects would be beneficial.[ncbi.nlm.nih.gov]
  • It is known that certain patients with congenital adrenal hyperplasia require very high substitution doses of cortisone acetate, and a few patients do not respond to this treatment at all.[ncbi.nlm.nih.gov]
  • Samples were analysed from days 1, 3 and 4 of life, before cortisone acetate treatment commenced on day 6, and on days 9 and 192, during treatment.[ncbi.nlm.nih.gov]
  • The decreased testicular function did not improve during the cortisone treatment.[ncbi.nlm.nih.gov]

Etiology

  • This method allows the assessment of 11β-HSD1/2 and 5α/β-reductase activities in a single analytical run providing an innovative tool to explain the potential etiology of depression.[ncbi.nlm.nih.gov]

Epidemiology

  • Saliva samples can be used for hormone analysis and are therefore excellent specimens in epidemiological studies.[ncbi.nlm.nih.gov]
  • PTSD symptoms were assessed with the PTSD Checklist (PCL), and depression symptoms with the Center for epidemiological studies depression scale (CES-D). Hair cortisone levels were quantified by liquid chromatography tandem mass spectrometer.[ncbi.nlm.nih.gov]
  • Their detection is relevant to epidemiological studies aimed at investigating the effects of circadian cycle disruption.[ncbi.nlm.nih.gov]
  • Beck Depression Inventory-II (BDI-II), Center for Epidemiological Studies Depression Scale (CES-D), Positive Affect Negative Affect Scale (PANAS), State-Trait Anxiety Inventory (STAI), Perceived Stress Scale (PSS) and EuroQoL and CushingQoL questionnaires[ncbi.nlm.nih.gov]
Sex distribution
Age distribution

Pathophysiology

  • Possible clinical and pathophysiological considerations are discussed.[ncbi.nlm.nih.gov]

Prevention

  • They were able to prevent, at least in part, both the cortisone- and the UV-mediated decreases in collagen content.[ncbi.nlm.nih.gov]
  • Although several animal data support gastro-protective effects of omega-3 fatty acids in the present case they were not able to prevent ulcer generation.[ncbi.nlm.nih.gov]
  • CRD is caused by inactivating mutations in the H6PD gene, rendering the 11beta-HSD1 enzyme unable to operate as an oxoreductase, preventing local glucocorticoid regeneration.[ncbi.nlm.nih.gov]
  • Still, it can be seen as a long term investment for some patients, as PRP therapy is known to postpone, and even prevent, the need for potential surgeries.[regenervate.com]
  • This treatment is about prevention as well and is very useful to prevent scarring — acne cysts are those prone to skin scars,” says Gross.[thefashionspot.com]

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