Presentation
We present 3 cases of significant bacteremia by C. amycolatum. Bacterial isoliations from blood culture were obtained using the Vital Systems. [ncbi.nlm.nih.gov]
Entire Body System
- Asymptomatic
RESULTS: A total of 402 strains of Corynebacterium species were isolated from 388 out of 714 asymptomatic subjects (carriage rate 54.3%). [ncbi.nlm.nih.gov]
Asymptomatic carriers are key factors in transmission, and neither natural infection nor vaccination prevents asymptomatic pharyngeal carriage. In temperate regions, transmission is higher in the winter months. [infectiousdiseaseadvisor.com]
- Chills
Abstract A 54-year-old female with a prosthetic mitral valve presented with a 3-day history of dizziness, subjective fever, and chills. Blood cultures were positive for a pleomorphic Gram-positive rod. [ncbi.nlm.nih.gov]
In this review we will summarize the knowledge about adaptation strategies of C. glutamicum to heat, oxidative, osmotic, and chill stress. [horizonpress.com]
Signs and symptoms may include: A thick, gray membrane covering the throat and tonsils A sore throat and hoarseness Swollen glands (enlarged lymph nodes) in the neck Difficulty breathing or rapid breathing Nasal discharge Fever and chills Tiredness In [mayoclinic.org]
- Laboratory Technician
Currently, in a clinical setting, many bacteriological laboratory technicians in hospitals report Corynebacterium species as “Gram-positive rods”. [intechopen.com]
- Surgical Procedure
Patients with C. kroppenstedtii presented with a hot painful breast mass and underwent multiple surgical procedures (median, 4 procedures; range, 2 to 6 procedures). [ncbi.nlm.nih.gov]
Most of the women underwent ⩾1 surgical procedure: 4 underwent 1 or 2 aspirations alone; 17 underwent 1–6 procedures (mean, 2.8 procedures), including incision and drainage, biopsy, and excision, as well as aspiration; and data were not available for [academic.oup.com]
- Rigor
Its enzymatic activity to transfer GlcNAc to 1L-Ins-1-P was confirmed by the isolation and rigorous characterization of its reaction product 3-phospho-1- D - myo -inositol-2-acetamido-2-deoxy-α- D -glucopyranoside. [pubs.rsc.org]
Jaw & Teeth
- Halitosis
The next day the child developed tender submandibular swelling, drooling, halitosis, and a high-pitched voice. [pediatrics.aappublications.org]
Skin
- Skin Disease
Erythrasma is a superficial skin disease caused by Gram-positive Corynebacterium species. Coral-red fluorescence under Wood's light, strongly suggestive of erythrasma, can be attributed to the presence of porphyrins. [ncbi.nlm.nih.gov]
Although non-toxigenic strains of C. diphtheriae have classically been considered harmless, researches show mounting evidences that they can cause skin diseases, subcutaneous infections, and invasive infections including endocarditis in certain situations [journals.plos.org]
Urogenital
- Hematuria
METHODS AND RESULTS: Here we report the case of a 75-year-old Caucasian man with a prolonged history of renal stones who was admitted for gross hematuria associated with renal failure. [ncbi.nlm.nih.gov]
Type your tag names separated by a space and hit enter Abstract This report presents the case history of a five-year-old Eringer cow suffering from chronic hematuria. [unboundmedicine.com]
- Dysuria
CASE REPORT A 27-year-old heterosexual Iranian man attended a private infectious disease clinic in Tehran, Iran, with a 5-day history of urethritis presenting with dysuria and a white-yellow urethral discharge. [journals.lww.com]
Workup
Microbiology
- Gram-Positive Rods
B: A large amount of Gram-positive rods and a few polymorphonuclear leukocytes were found. [intechopen.com]
Gram positive rods are arranged singly or in pairs often in a ‘V’ formation. Identification by automated methods can be undertaken from suspect colonies. If, the laboratory does not have an automated method, follow the biochemical test pathway. [gov.uk]
Multiple blood cultures grew a gram-positive rod, Corynebacterium pseudodiphtheriticum. He was taken to the operating room for removal of the vegetative endocarditis and pulmonary valve replacement. [ncbi.nlm.nih.gov]
- Staphylococcus Aureus
We found pathogenic bacteria in following frequency: 18.7% Staphylococcus aureus, 12.1 % C macginleyi, 10.3% Streptococcus pneumoniae, 8.4% Haemophilus influenzae. [bjo.bmj.com]
We describe a patient who developed Corynebacterium striatum native valve endocarditis after receiving two 6-week courses of daptomycin for the treatment of methicillin-resistant Staphylococcus aureus bacteremia and osteomyelitis. [ncbi.nlm.nih.gov]
aureus and group A streptococci Invasive disease Endocarditis Mycotic aneurysms Osteomyelitis Septic arthritis Prevention Vaccination ARUP Laboratory Tests References Medical Experts [arupconsult.com]
Treatment
Treatment The specific treatment for diphtheria consists of administration of antitoxin with dose of 20,000–100, 000 units of ADS intramuscularly and antibiotic therapy using penicillin. [brainkart.com]
We conclude that the optimal duration of the antibiotic treatment for relapsing C. striatum bacteraemia from a chronic ulcer should be 6 weeks together with surgical treatment. [ncbi.nlm.nih.gov]
Prognosis
METHODS: We reviewed the medical records of all patients from whom C. striatum isolates were recovered from blood culture for analysis of the patients' backgrounds and clinical course including response to antimicrobial therapy and prognosis. [ncbi.nlm.nih.gov]
Prognosis Trichomycosis axillaris is a benign infection of the hair with no associated mortality or complications. Once treated, it may recur if preventive measures (eg, shaving, antibacterial soap, antiperspirants) are not taken. [emedicine.com]
[…] pertussis 5 doses before school-age, completed by 4-6 years of age Tdap vaccine booster vaccine at 11-12 years of age should also be given to pregnant mothers and those around them Td vaccine tetanus and diphtheria toxoid vaccine at 10-year intervals Prognosis [medbullets.com]
Etiology
C. propinquum should be recognized as a potential pathogen and included in the etiologic diagnostic algorithm, particularly in patients with immunosuppressive conditions. [ncbi.nlm.nih.gov]
Diphtheria and its Etiological Agents Pages 1-14 Corynebacterium diphtheriae, Corynebacterium ulcerans and Corynebacterium pseudotuberculosis—General Aspects Guaraldi, Ana Luíza de Mattos (et al.) [springer.com]
Epidemiology
Members Projects Software Partners Publications Download 2021 Genomic epidemiology and strain taxonomy of Corynebacterium diphtheriae., J Clin Microbiol 2021 Sep; (): JCM0158121. 2021 Badell E, Alharazi A, Criscuolo A, Almoayed KAA, Lefrancq N, Bouchez [research.pasteur.fr]
Sign in Original ArticleFree PreviewArchive Corynebacterium diphtheriae Skin Infections in Alabama and Louisiana — A Factor in the Epidemiology of Diphtheria List of authors. Mark A. Belsey, M.D., M.P.H., and T.M., Michael Sinclair, M.D., M. [nejm.org]
CONCLUSIONS: CKSM is a useful addition to routine agar media for the isolation of C. kroppenstedtii, and will be helpful for studying the epidemiology and transmission of this unusual Corynebacterium causing granulomatous mastitis. © Article author(s) [ncbi.nlm.nih.gov]
Pathophysiology
However, little is known about the pathophysiological pathway implicated in Corynebacterium BJI, species distribution and antimicrobial susceptibility, and the management of these difficult-to-treat clinical entities. [clinicaltrials.gov]
Transmission – airborne or direct contact (respiratory secretions or skin lesion) Organism Gram-positive bacillus Not spore forming Unencapsulated Pleomorphic Produces exotoxin that causes many of the symptoms Results in asymptomatic carriage in some patients Pathophysiology [arupconsult.com]
Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test Corynebacterium diphtheriae is the etiological agent of diphtheria and occurs in 2 forms, respiratory and cutaneous diphtheria [mayomedicallaboratories.com]
When the pubic hair is affected, the condition is referred to as trichomycosis pubis. [1] Shelley and Shelley noted the coexistence of erythrasma, trichomycosis axillaris, and pitted keratolysis and termed it the corynebacterial triad. [2] Pathophysiology [emedicine.com]
Prevention
Simple, rapid screening tests should be used to differentiate it from C. diphtheriae and hence, to prevent unnecessary concern in community. [ncbi.nlm.nih.gov]
Prevention Prevention of infections caused by coryneform bacteria includes- proper skin antisepsis before invasive procedures and precaution when handling animals. Further Readings Bailey & Scott’s Diagnostic Microbiology. Editors: Bettey A. [universe84a.com]