Presentation
2003 - present Yellow Fever 1930 - present [diseases.canada.ca]
A personal presentation format simulates the clinical experience of asking advice of a trusted colleague. Algorithms and patient resource information complement each chapter. Succinct therapeutic chapters are ideal study tools for the exams. [books.google.de]
They are present all over the world, and spread by fecal-oral route. About 90% of infections don't cause symptoms or present with a fever only. Infants and young kids are particularly susceptible to symptomatic coxsackie. [webmd.com]
Snapshot A 16-year-old boy presents to the emergency room for chest pain and shortness of breath. He has no history of congenital heart disease. He recently attended a month-long camp with other teenagers, several of whom had viral illnesses. [medbullets.com]
Patients present with fever and sharp, paroxysmal, spasmodic pain in the chest and upper abdomen. All patients recover completely within 1 week. [emedicine.medscape.com]
Immune System
- Splenomegaly
[…] the Coxsackie viruses include herpangina, 2 3 4 "three-day fever," 4 aseptic meningitis, 5 6 7 8 9 10 11 epidemic pleurodynia, 12 13 14 pericarditis, 15 16 17 18 myocarditis in infants, 19 20 21 22 23 orchitis 24 and a syndrome of lymphadenopathy and splenomegaly [nejm.org]
Hepatitis B and C predispose to hepatocellular carcinoma JCV causes progressive multifocal leukoencephalopathy Measles causes subacute sclerosis panencephalitis Herpes simplex virus encephalitis Rabies encephalitis Poliomyelitis Epstein Barr virus causes splenomegaly [ncbi.nlm.nih.gov]
Entire Body System
- Malaise
Between the two extremes, most patients report dyspnea, chest pain, fever, and malaise. Symptoms may be preceded by an upper respiratory infection within the preceding 7-14 days. [emedicine.medscape.com]
Malaise 6. Drowsiness 7. Sore throat 8. Myalgia 9. Nausea 10. Vomiting There may also be (but not commonly): 11. Photophobia 12. Tinnitus (noise in the ears) 13. Vertigo 14. Chest and abdominal pain 15. [atsu.edu]
Steps for of diagnosis of hand, foot and mouth disease Steps for diagnosis include (1-6): Clinical history of fever, sore throat, malaise, headache and general feeling of unwell is commonly seen. [news-medical.net]
Other HFMD symptoms include the following: Fever Reduced appetite Sore throat Malaise The symptoms generally appear in stages and the incubation period is usually 3 to 6 days. 2 The most common complication is dehydration. [pharmacytimes.com]
Respiratoric
- Pleuritic Pain
Pain on inspiration is similar to pleuritic pain and pulmonary embolism may be suspected. The muscles are locally tender. Fever, headache or nonspecific abdominal pain - either as prodromal symptoms or with the onset of chest pain. [patient.info]
Cardiovascular
- Heart Failure
(such as heart failure in myocarditis) Conservative supportive care indication all patients modalities antipyretics analgesics hydration Complications Aseptic meningitis Guillain-Barre syndrome Please rate topic. [medbullets.com]
Severely affected infants become listless or unresponsive and may have myopericarditis/heart failure, pneumonia, or an inflamed liver ( hepatitis ) or liver failure. [emedicinehealth.com]
Furthermore, patients may also require heart failure therapy and treatment of arrhythmias. Differential Diagnosis Overlap of symptoms occurs amongst various viral infections. [ncbi.nlm.nih.gov]
Manifestations of myopericarditis range from an asymptomatic presentation to heart failure and death. Between the two extremes, most patients report dyspnea, chest pain, fever, and malaise. [emedicine.medscape.com]
- Left Ventricular Dysfunction
An echo shows left ventricular dysfunction and a cardiac magnetic resonance imaging reveals myocarditis. Serology confirms that the etiology is viral. [medbullets.com]
Myocarditis Coxsackievirus B is one of the more common causes of myocarditis, with potential to progress to dilated cardiomyopathy. [ 6 ] Viral myocarditis may be asymptomatic, or may present with symptoms of heart failure and left ventricular dysfunction [patient.info]
High prevalence of viral genomes and multiple viral infections in the myocardium of adults with "idiopathic" left ventricular dysfunction. Circulation. 2005 Feb 22;111(7):887-93. [PubMed: 15699250] 2. [ncbi.nlm.nih.gov]
Skin
- Eruptions
Symptoms include a sore throat, fever, rashes, and vesicular eruptions that can ulcerate. Pleurodynia. Known as the inflammation of the chest muscles, pleurodynia can cause sudden pain in the upper abdomen and chest. Hemorrhagic conjunctivitis. [belmarrahealth.com]
Coxsackievirus A4 causes a widespread vesicular eruption. There has been some investigation into Coxsackievirus B4 as a possible part of the aetiology of type 1 diabetes mellitus. [patient.info]
The incubation period also varies within syndromes, and maximum transmission occurs within the first two weeks of infection.[19] Exanthema presents as maculopapular eruptions surrounded by an erythematous halo. [ncbi.nlm.nih.gov]
- Erythema
Coxsackievirus B5 causes pustular stomatitis with erythema multiforme. Coxsackievirus A4 causes a widespread vesicular eruption. [patient.info]
Musculoskeletal
- Back Pain
[…] infant's head) Noticeably different temperament A purple-red splotchy rash In children older than one year: Neck and/or back pain Headache Sleepiness Confusion Irritability Fever Refusing to eat Decreased level of consciousness Seizures Photophobia [stanfordchildrens.org]
The symptoms associated with these complications include high fever, headache, legarthy, irritability, stiff neck, and back pain. If your child has any of these additional symptoms, you should seek medical attention. What Causes Coxsackievirus vs. [emedicinehealth.com]
Neurologic
- Headache
When the conjunctiva of the eye become inflamed, symptoms including pain and swelling of the eye, red eye, and headache may occur. Hepatitis. [belmarrahealth.com]
Diagnosis and Treatment Meningitis is initially diagnosed based on the symptoms, specifically the headache and stiff neck symptoms. [innerbody.com]
A twenty-two-year-old woman was admitted to the hospital in Honolulu, Hawaii, at term with chills, fever and severe frontal headache. Nasal congestion and a nonproductive cough had. .. [nejm.org]
Aseptic meningitis Patients with aseptic meningitis may have rapid or gradual onset of fever and chills, nausea and vomiting, malaise, headaches, neck pain, light sensitivity, and upper respiratory symptoms. [emedicine.medscape.com]
- Confusion
It is often confused with foot-and-mouth disease (also known as hoof-and-mouth disease), which affects cattle, sheep, and swine. Pharmacists can play an important role in counseling patients on symptoms and prevention strategies. [pharmacytimes.com]
DIFFERENTIAL DIAGNOSIS : Viral meningitis may be confused with: 1. Bacterial meningitis 2. Brucellosis 3. Listeriosis 4. Leptospirosis 5. Tuberculosis 6. Syphilis 7. Lymphogranuloma venereum 8. Typhus 9. Mycoplasmal pneumonia 10. Malignancy 11. [atsu.edu]
If there is confusion about the exact diagnosis, an infectious-disease specialist may be consulted. A cardiologist or intensive-care specialist may be needed for the management of severe complications. [emedicinehealth.com]
Others, such as headache and confusion, are hard to decipher in a baby. Your baby might also be crying constantly and have a bulging fontanel (soft spot on his head). [babycenter.com]
However other symptoms may be confusing and often appear similar. Herpes infections. This could be herpes simplex infections or a recurrence of chicken pox lesions called Herpes zoster. [news-medical.net]
- Neck Stiffness
Clinical examination revealed neck stiffness and positive Kernig and Brudzinski signs. The remaining examination was noncontributory. [journals.lww.com]
As the inflammation worsens, headache and neck stiffness develop. Some people do not experience any symptoms. Symptoms in babies: High fever Irritability Sleepiness Poor appetite Bulge on the soft spot on the head ( fontanel ) Stiff neck or body. [innerbody.com]
[…] and/or back pain Headache Sleepiness Confusion Irritability Fever Refusing to eat Decreased level of consciousness Seizures Photophobia (sensitivity to light) Nausea and vomiting Neck stiffness A purple-red splotchy rash The symptoms of meningitis may [stanfordchildrens.org]
It is recommended that people with enterovirus infections seek medical attention if they start to experience pain in the chest or abdomen, a sore throat that does not improve, difficulty in breathing, severe headaches, neck stiffness, or vomiting. [humanillnesses.com]
- Flaccid Paralysis
paralysis 587 Protothecosis and chlorellosis 597 Pseudocowpox 598 Pyodermas impetigo abscess etc 599 Pyomyositis 600 Qfever 601 Rabies 604 Rat bite fever spirillary 611 Rat bite fever streptobacillary 612 Relapsing fever 613 Respiratory syncytial virus [books.google.es]
paralysis Enteroviruses 70 and 71 and coxsackievirus A7 can cause similar syndrome Meningitis beyond neonatal period characterized by sudden onset of fever (38°-40°C) Meningeal irritation (>6 weeks) occurs in >50% of patients Headache and photophobia [arupconsult.com]
AIDS 1986 - presentAcute Flaccid Paralysis (AFP)2000 - present Anthrax 1930 - 1982, 2002 - present Botulism 1933 - present Brucellosis 1928 - presentOriginally called 'undulant fever' Campylobacteriosis 1986 - present Chickenpox (Varicella) 1924 - 1958 [diseases.canada.ca]
paralysis, and the related acute flaccid myelitis. [tr-ex.me]
- Rabies
If you have rabies, you will be treated with the rabies vaccine over several days as well as receiving immune globulin. Individuals infected with HIV will receive antiretroviral therapy. Meningitis from these viruses may require hospitalization. [drweil.com]
Plesiomonas infection 580 Pleurodynia 582 Pneumocystis pneumonia 583 Pneumonia bacterial 585 Poliomyelitis and acute flaccid paralysis 587 Protothecosis and chlorellosis 597 Pseudocowpox 598 Pyodermas impetigo abscess etc 599 Pyomyositis 600 Qfever 601 Rabies [books.google.es]
Pertussis 1924 - presentAlso known as whooping cough Plague 1930 - present Poliomyelitis 1924 - presentNon-paralytic poliomyelitis was presented in the viral meningitis category starting in 1962 Rabies 1927 - present Rubella 1924 - 1958, 1969 - presentAlso [diseases.canada.ca]
Viruses that can cause aseptic meningitis include the following: chickenpox HIV herpes simplex mumps measles West Nile rabies You can contract viruses by coming into contact with an infected person’s cough, saliva, or fecal matter. [healthline.com]
Workup
Polymerase chain reaction is a rapid and sensitive diagnostic test for the identification of enteroviruses in cerebrospinal fluid, blood, urine, and throat specimens and should be performed as part of the general workup in the evaluation of a febrile [nursingcenter.com]
Biopsy
- Hepatocellular Carcinoma
These include: Human immunodeficiency virus Hepatitis B and C predispose to hepatocellular carcinoma JCV causes progressive multifocal leukoencephalopathy Measles causes subacute sclerosis panencephalitis Herpes simplex virus encephalitis Rabies encephalitis [ncbi.nlm.nih.gov]
Treatment
This edition adds new general treatment categories, including plasmaphoresis, corticosteroid treatment, and IV IgG. A CD-ROM containing the complete previous edition enables you to access additional opinions. [books.google.de]
Treatment with ceftriaxone 100 mg/kg once a day was initiated. [journals.lww.com]
In addition, treatment with pleconaril may have affected the severity of the encephalitis. [nursingcenter.com]
[Article in Russian] PMID: 7518170 [The clinical diagnosis and treatment of meningitis caused by Coxsackie B viruses] [Article in Russian] L S Bondarev et al. Lik Sprava. 1993 Oct-Dec. [pubmed.ncbi.nlm.nih.gov]
Prognosis
This article reviews the pathogenesis, clinical manifestations, and differential diagnoses of enteroviral infections, specifically focusing on the prevention, treatment, and prognosis of the disease and the implications for clinical practice. [nursingcenter.com]
The prognosis of HFMD is excellent, with the vast majority resolving spontaneously in 5-10 days. [patient.info]
Cat-scratch disease PROGNOSIS : Full recovery with no sequelae THERAPY : Bed rest, analgesic drugs, repletion and conservation of fluids and electrolytes. [atsu.edu]
[…] common in children demographics more common in children risk factors exposure to others with the virus daycare centers poor hygiene finger sucking Pathogenesis once infected, the virus will travel to the lymph nodes and incubate, causing a prodrome Prognosis [medbullets.com]
The mortality rate is low, and the prognosis in children is believed to be better than that in adults. Complications include pericardial effusion, arrhythmia, heart block, valvular dysfunction, and dilated cardiomyopathy. [emedicine.medscape.com]
Etiology
When difficulties arise, it is pertinent to consider a viral etiology for the underlying illness and obtain a detailed maternal and infant history focusing on clinical symptoms, seasonality, geographic location, exposure, and incubation period. [nursingcenter.com]
Fed Proc. 1950 Sep; 9 (3):581–584. [ PubMed ] [ Google Scholar ] WELLER TH, ENDERS JF, BUCKINGHAM M, FINN JJ., Jr The etiology of epidemic pleurodynia: a study of two viruses isolated from a typical outbreak. [ncbi.nlm.nih.gov]
In 183 short chapters, the book provides the essentials clinicians need on symptoms/signs, diagnostic tests, and neurologic disorders of all etiologies. For this edition, Timothy A. [books.google.de]
[…] of myocarditis in infants, thought to be due to Coxsackie virus, were described from Southern Rhodesia 1 and Transvaal. 2 More recently, they have been reported in Holland 3 and the United States. 4 There was doubt that Coxsackie virus could be the etiologic [nejm.org]
Occurs in both outbreak and sporadic forms Etiology and Pathophysiology In immunocompetent hosts, VM is generally caused by a systemic viral infection with neurotropic predilection. [unboundmedicine.com]
Epidemiology
Weekly Epidemiological Record = Relevé épidémiologique hebdomadaire, 71 (34), 258. https://apps.who.int/iris/handle/10665/229866 Journal Weekly Epidemiological Record = Relevé épidémiologique hebdomadaire, 71 (34): 258 Language English français Collections [apps.who.int]
EPIDEMIOLOGICAL AND VIROLOGICAL STUDIES OF ECHOVIRUS TYPE 4 MENINGITIS IN JAPAN, 1964. Japanese Journal of Medical Science and Biology, Vol. 21, Issue. 1, p. 11. [cambridge.org]
However, because of the limit data of Chinese CVA9 strains available, it was very difficult to clarify the molecular epidemiology of CVA9 in China. [virologyj.biomedcentral.com]
Outbreak of aseptic meningitis caused by Coxsackie B5 virus; laboratory, clinical, and epidemiologic study. J Am Med Assoc. 1957 Aug 31; 164 (18):2015–2019. [ PubMed ] [ Google Scholar ] RHODES AJ, BEALE A. [ncbi.nlm.nih.gov]
Pathophysiology
This book puts major emphasis on treatment, with diagnosis, epidemiology, and pathophysiology discussed only when they affect treatment strategies and decisions. Inclusive coverage allows you to treat the gamut of neurologic diseases effectively. [books.google.de]
Occurs in both outbreak and sporadic forms Etiology and Pathophysiology In immunocompetent hosts, VM is generally caused by a systemic viral infection with neurotropic predilection. [unboundmedicine.com]
Pleurodynia is most common amongst adults.[10] Out of the 21 viruses that can cause cardiovascular disease, the coxsackie B virus is the major cause of viral myocarditis, especially in neonates and younger children.[15][16] Pathophysiology The pathogenesis [ncbi.nlm.nih.gov]
Pathophysiological Characteristics In most of case epidemic hand-foot-and-mouth disease (HFMD) viral infections are caused by coxsackievirus A16, A6, or enterovirus 71. [juniperpublishers.com]
J Med Virol 87:1471–1479 View Article Google Scholar Jain S, Patel B, Bhatt GC (2014) Enteroviral encephalitis in children: clinical features, pathophysiology, and treatment advances. [springerplus.springeropen.com]
Prevention
This article reviews the pathogenesis, clinical manifestations, and differential diagnoses of enteroviral infections, specifically focusing on the prevention, treatment, and prognosis of the disease and the implications for clinical practice. [nursingcenter.com]
Special attention is given to the prevention and treatment of these diseases found in developing countries as well as the latest findings about new antimicrobial agents, gram-negative infections and their management, and recommendations for immunization [books.google.com]
Vaccines can help prevent you from getting many viral diseases. [icdlist.com]
Centers for Disease Control and Prevention. "Hand, Foot, and Mouth Disease." Dec. 22, 2017.. United States. Centers for Disease Control and Prevention. [medicinenet.com]