Presentation
Patients present with flulike symptoms; higher fever than present in typical HFMD; and a longer duration of disease, typically lasting 2 weeks. [mdedge.com]
They are present all over the world, and spread by fecal-oral route. About 90% of infections don't cause symptoms or present with a fever only. Infants and young kids are particularly susceptible to symptomatic coxsackie. [webmd.com]
The present significance of this case is discussed. [ncbi.nlm.nih.gov]
Entire Body System
- Rigor
[bsid1269201] Cell surface interactions at the vascular wall Cell surface interactions at the vascular wall Leukocyte extravasation is a rigorously controlled process that guides white cell movement from the vascular lumen to sites of tissue inflammation [ncbi.nlm.nih.gov]
- Painter
Bergman I, Painter MJ, Wald ER, et al. Outcome in children with enteroviral meningitis during the first year of life. J Pediatr. 1987 May. 110(5):705-9. [Medline]. Berlin LE, Rorabaugh ML, Heldrich F, et al. [emedicine.medscape.com]
Immune System
- Cervical Lymphadenopathy
Initial observations included a prominent cervical lymphadenopathy, exudative pharyngitis and leucocytosis with atypical lymphocytosis. At the end of the 2nd week of illness the patient developed meningoencephalomyelitis and haemolytic anaemia. [ncbi.nlm.nih.gov]
Jaw & Teeth
- Exudative Pharyngitis
Initial observations included a prominent cervical lymphadenopathy, exudative pharyngitis and leucocytosis with atypical lymphocytosis. At the end of the 2nd week of illness the patient developed meningoencephalomyelitis and haemolytic anaemia. [ncbi.nlm.nih.gov]
Fetus
- Spontaneous Rupture of Membranes
Delivery occurred vaginally approximately 24 hours later, following spontaneous rupture of membranes. At birth, both twins showed signs of sepsis. [ncbi.nlm.nih.gov]
Urogenital
- Polyuria
A 65-year-old Japanese man presented to our hospital in June 2013 with a 6-day history of fever and fatigue, a 24-h history of thirst, and polyuria. His temperature was 37.8°C and he was alert. [ncbi.nlm.nih.gov]
Neurologic
- Cerebellar Ataxia
Neurological involvement associated with enterovirus 71 infection may include: Aseptic meningitis Encephalitis Encephalomyelitis Acute cerebellar ataxia Acute transverse myelitis Guillain-Barré syndrome Opsomyoclonus syndrome Benign intracranial hypertension [dermnetnz.org]
- Dizziness
A 7 year old boy had 2 episodes of mental dizziness and consciousness disturbance. Because of he presented a visus of 70 %, headaches and vomiting he was admitted to our hospital. [ncbi.nlm.nih.gov]
Workup
Serum
- Hypertriglyceridemia
To our knowledge, pancreatitis, in the absence of hypertriglyceridemia in a CAPD patient, has not been previously reported. [ncbi.nlm.nih.gov]
DISCUSSION Acute pancreatitis may have diverse etiologies such as alcohol ingestion (acute or chronic), gallstones, drugs and toxins, metabolic disorders (hypertriglyceridemia, hypercalcaemia, and others), connective tissue diseases, infections, and others [pancreas.imedpub.com]
Microbiology
- Vibrio Vulnificus
[…] perfringens [C. perfringens] as the cause of diseases classified elsewhere B96.8 Other specified bacterial agents as the cause of diseases classified elsewhere B96.81 Helicobacter pylori [H. pylori] as the cause of diseases classified elsewhere B96.82 Vibrio [icd10data.com]
- Clostridium Perfringens
perfringens [C. perfringens] as the cause of diseases classified elsewhere B96.8 Other specified bacterial agents as the cause of diseases classified elsewhere B96.81 Helicobacter pylori [H. pylori] as the cause of diseases classified elsewhere B96.82 [icd10data.com]
- Helicobacter Pylori
pylori [H. pylori] as the cause of diseases classified elsewhere B96.82 Vibrio vulnificus as the cause of diseases classified elsewhere B96.89 Other specified bacterial agents as the cause of diseases classified elsewhere B97 Viral agents as the cause [icd10data.com]
Treatment
Due to its crucial role for viral entry, CAR-downregulation may lead to novel approaches for treatment for viral myocarditis. [doi.org]
Diagnostic procedures and treatment should be tailored to the specific disease manifestation. [amboss.com]
It does not provide medical advice, diagnosis or treatment. This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. [immuno-oncologynews.com]
At the end of the treatment period, mean ± S.D. [academic.oup.com]
Is there any treatment for coxsackievirus infection? There is no specific treatment for this typically self-limited disease (the symptoms resolve without specific antiviral treatment in about two to 10 days). [rxlist.com]
Prognosis
almost always self‑limiting Coxsackie B Myocarditis Pleurodynia Characteristics : highly contagious Clinical presentation Flu‑like symptoms Sudden thoracic and upper abdominal pain caused by irritation of the pleura and muscles Prognosis : self‑limiting [amboss.com]
We concluded that coxsackie virus B 4 caused acute encephalitis with ophthalmological and mental symptoms and good prognosis. Coxsackie virus B 4 should be considered in patients with encephalitis. [ncbi.nlm.nih.gov]
The prognosis of HFMD is excellent, with the vast majority resolving spontaneously in 5-10 days. [patient.info]
Etiology
The incidence of pancreatitis of unknown etiology may even be higher since the diagnosis of acute pancreatitis can be difficult and may go undetected. [pancreas.imedpub.com]
Vesicular exsanthema on palms suggested enterovirus as a possible etiologic agent. [jcm.asm.org]
Our patient is the first reported case of FT1D associated with Coxsackie virus A2 infection and supports the etiological role of common viral infections in FT1D. [ncbi.nlm.nih.gov]
Epidemiology
Weekly Epidemiological Record = Relevé épidémiologique hebdomadaire, 46 (25), 248 - 249. https://apps.who.int/iris/handle/10665/218374 Journal Weekly Epidemiological Record = Relevé épidémiologique hebdomadaire, 46 (25): 248 - 249 [apps.who.int]
Epidemiology Worldwide distribution Occur in all age groups Highest incidence in infants and young children ( < 10 years ) References: [1] Epidemiological data refers to the US, unless otherwise specified. [amboss.com]
Epidemiology and control of hand, foot and mouth disease in Singapore, 2001-2007. Ann Acad Med Singapore. 2009 Feb. 38(2):106-12. [Medline]. Bergman I, Painter MJ, Wald ER, et al. [emedicine.medscape.com]
The differentiation between EV70 and the CA24 variant as the agent causing AHC is very important in epidemiology, especially as there is a high possibility in Japan of outbreaks caused by these two agents. [ncbi.nlm.nih.gov]
Pathophysiology
Pathophysiology Coxsackieviruses are transmitted primarily via the fecal-oral route and respiratory aerosols, although transmission via fomites is possible. The viruses initially replicate in the upper respiratory tract and the distal small bowel. [emedicine.medscape.com]
Prevention
Centers for Disease Control and Prevention. "Hand, Foot, and Mouth Disease." Dec. 22, 2017.. United States. Centers for Disease Control and Prevention. [medicinenet.com]
Is it possible to prevent coxsackievirus infections? Prevention of coxsackievirus infections is difficult but possible. [rxlist.com]
[…] contagious, and can be prevented. [microbewiki.kenyon.edu]