Interestingly, erythrocytes from neither mice nor rhesus macaques present CAR. [ncbi.nlm.nih.gov]

Patients present with flulike symptoms; higher fever than present in typical HFMD; and a longer duration of disease, typically lasting 2 weeks. [mdedge.com]

• Inflammation

  Pathways for the CXADR gene Viral myocarditis Viral myocarditis Myocarditis is a cardiac disease associated with inflammation and injury of the myocardium. [ncbi.nlm.nih.gov]

• Congestive Heart Failure

  Etiologies of cardiomyopathy and heart failure. Nat Med. 1999; 5 : 266–267. Crossref Medline Google Scholar 23 Braunwald E, Bristow M. Congestive heart failure. Circulation. 2000; 102 : IV-14–IV-23. Link Google Scholar 24 Horwitz M. [doi.org]

  Effects of enalapril on mortality in severe congestive heart failure: results of the Cooperative North Scandanavian Enalapril Survival Study (CONSENSUS). N Engl J Med. 1987 ; 316 : 1429 –35. 4 Kearney MT, Cotton JM, Richardson PJ et al. [academic.oup.com]

• Common Cold

  The symptoms are much like a common cold with a rash The rash appears as blisters or ulcers in the mouth, on the inner cheeks, gums, sides of the tongue, and as bumps or blisters on the hands, feet, and sometimes other parts of the skin. [phpa.health.maryland.gov]

  Those with a common cold or rash usually don’t require any complex testing and can be diagnosed based on symptoms, though a throat swab may be taken to rule out strep throat. [belmarrahealth.com]

  Cavatak consists of a live common cold virus, called coxsackievirus A21, which has the ability to attack and kill a wide range of cancer cells. [immuno-oncologynews.com]

  The virus is one cause of the common cold or a generalized mildly erythematous (red) rash, especially seen in the summer months. It may also cause diarrhea or a sore throat that is similar to strep throat. [emedicinehealth.com]

• Pleuritic Pain

  Pain on inspiration is similar to pleuritic pain and pulmonary embolism may be suspected. The muscles are locally tender. Fever, headache or nonspecific abdominal pain - either as prodromal symptoms or with the onset of chest pain. [patient.info]

• Abdominal Pain

  The children can have a wide array of symptoms with this virus, they can have fever with no symptoms, they could have sore throat, abdominal pain, nausea. The most widely known version of this infection is Hand, Foot and Mouth Disease. [kidsinthehouse.com]

  Coxsackie virus es cause sore throat or fever with chest or abdominal pains. [britannica.com]

  […] hands and feet Oral ulcers Diagnosis : clinical Treatment : symptomatic Prognosis : almost always self‑limiting Coxsackie B Myocarditis Pleurodynia Characteristics : highly contagious Clinical presentation Flu‑like symptoms Sudden thoracic and upper abdominal [amboss.com]

  Pain on inspiration is similar to pleuritic pain and pulmonary embolism may be suspected. The muscles are locally tender. Fever, headache or nonspecific abdominal pain - either as prodromal symptoms or with the onset of chest pain. [patient.info]

• Loss of Appetite

  Most children will complain of a sore throat or sore mouth and loss of appetite. Fever of 101-102 lasts 1-2 days and is usually accompanied by sores in the mouth. Sores can also occur on the hands and feet and occasionally on the buttocks. [portal.ct.gov]

  The initial symptoms include fever, loss of appetite, and sore throat, followed by small blisters in the mouth and a red skin rash commonly found on the palms and soles. [uspharmacist.com]

  Symptoms include: Fever Headache Loss of appetite Rash with very small blisters on the hands, feet, and diaper area that may be tender or painful when pressed Sore throat Ulcers in the throat (including tonsils), mouth, and tongue The health care provider [medlineplus.gov]

  The common symptoms of Coxsackie virus are fever, sore throat, fatigue and loss of appetite. It would be only for two or three days. Then it appears as sores and blisters on the mouth, throat and hands. [diseasespictures.com]

• Dysphagia

  with 74% of those cases testing PCR positive for coxsackievirus A6; about 25% of reported cases were in adults. [5] Herpangina is a vesicular enanthem of the posterior oropharynx with fever, sore throat, occasional throat exudate, odynophagia, and dysphagia [emedicine.medscape.com]

  Mild pyrexia, headache, sore throat, dysphagia, loss of appetite and sometimes vomiting and abdominal pain occur. [patient.info]

• Heart Failure

  Five patients had died, two of them had had heart failure. Thirteen patients and 23 healthy control subjects underwent exercise testing with gas exchange analysis. [ncbi.nlm.nih.gov]

  (such as heart failure in myocarditis) Conservative supportive care indication all patients modalities antipyretics analgesics hydration Complications Aseptic meningitis Guillain-Barre syndrome Please rate topic. [medbullets.com]

  […] pattern generally seen in severe heart failure. [doi.org]

  In general, patients with dilated cardiomyopathy will benefit from agents commonly used in heart failure, since their symptoms and presentation are similar. Conclusion. [academic.oup.com]

• Vesicular Rash

  rash on the hands and feet Oral ulcers Diagnosis : clinical Treatment : symptomatic Prognosis : almost always self‑limiting Coxsackie B Myocarditis Pleurodynia Characteristics : highly contagious Clinical presentation Flu‑like symptoms Sudden thoracic [amboss.com]

  […] on palms and soles but is often not macular and not vesicular in nature Chickenpox distinguishing factor itchy vesicular rash that typically does not occur on the palms, soles, and oral mucosa Treatment Management approach mainstay of treatment is supportive [medbullets.com]

  On admission, the patient gave a history of previous febrile illness with vesicular rash on palms and soles, and his sister had same symptoms, which suggested a contagious disease as an etiology. [jcm.asm.org]

  Serious enteroviral infection can lead to: Widespread vesicular rash Enteritis (gut infection ) Myocarditis (heart muscle infection ) Meningoencephalitis (brain infection ) Acute flaccid paralysis (spinal cord infection ) Pulmonary oedema and pneumonia [dermnetnz.org]

• Rash of the Hands and Feet

  foot, and mouth disease Characteristics : highly contagious Clinical presentation General symptoms: fever, reduced general condition Skin/mucosa Maculopapular and partially vesicular rash on the hands and feet Oral ulcers Diagnosis : clinical Treatment [amboss.com]

  The rash on the hands and feet is typically seen later in the illness, and can last up to 10 days. The hands and feet may peel as the rash is resolving. Dehydration is the main concern, as many children refuse liquids due to mouth and throat pain. [childrenshealthpartners.com]

  Usually, a diagnosis can be made from asking about the symptoms and the rash on the hands and feet. There is no specific treatment for the infection other than symptom relief. Antibiotics do not work because the infection is caused by a virus. [medlineplus.gov]

• Hydrops Fetalis

  Intrauterine adenoviral myocarditis presenting as non-immune hydrops fetalis: diagnosis by polymerase chain reaction. Pediatr Infect Dis J. 1994 ; 13 :144–150. [doi.org]

• Redness of Eye

  Herpangina : Causes a throat infection, including red-ringed blisters and ulcers on the tonsils and soft parts of throat and mouth. Hemorrhagic conjunctivitis : Causes eye pain, red, watery eyes, swelling, light sensitivity and blurred vision. [sheknows.com]

  Hemorrhagic conjunctivitis usually begins as eye pain, followed quickly by red, watery eyes with swelling, light sensitivity, and blurred vision. [rchsd.org]

  Hemorrhagic conjunctivitis, an infection that affects the whites of the eyes, usually begins as eye pain, followed quickly by red, watery eyes with swelling, light sensitivity, and blurred vision. [kidshealth.org]

• Cerebellar Ataxia

  Neurological involvement associated with enterovirus 71 infection may include: Aseptic meningitis Encephalitis Encephalomyelitis Acute cerebellar ataxia Acute transverse myelitis Guillain-Barré syndrome Opsomyoclonus syndrome Benign intracranial hypertension [dermnetnz.org]

• Hyperactivity

  There was marked increase in tone with cogwheel rigidity in upper extremities and hyperactive deep tendon reflexes; bilateral ankle clonus was noted but with equivocal Babinski signs. [jamanetwork.com]

It does not provide medical advice, diagnosis or treatment. This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. [immuno-oncologynews.com]

Due to its crucial role for viral entry, CAR-downregulation may lead to novel approaches for treatment for viral myocarditis. [doi.org]

At the end of the treatment period, mean ± S.D. [academic.oup.com]

It most commonly causes sore throats, and symptoms will go away without treatment. However, in some cases Coxsackie virus may be more serious, and treatment with herbal remedies may be helpful in relieving symptoms and speeding recovery. [livestrong.com]

Diagnostic procedures and treatment should be tailored to the specific disease manifestation. [amboss.com]

We concluded that coxsackie virus B 4 caused acute encephalitis with ophthalmological and mental symptoms and good prognosis. Coxsackie virus B 4 should be considered in patients with encephalitis. [ncbi.nlm.nih.gov]

almost always self‑limiting Coxsackie B Myocarditis Pleurodynia Characteristics : highly contagious Clinical presentation Flu‑like symptoms Sudden thoracic and upper abdominal pain caused by irritation of the pleura and muscles Prognosis : self‑limiting [amboss.com]

The prognosis of HFMD is excellent, with the vast majority resolving spontaneously in 5-10 days. [patient.info]

The incidence of pancreatitis of unknown etiology may even be higher since the diagnosis of acute pancreatitis can be difficult and may go undetected. [pancreas.imedpub.com]

Our patient is the first reported case of FT1D associated with Coxsackie virus A2 infection and supports the etiological role of common viral infections in FT1D. [ncbi.nlm.nih.gov]

Vesicular exsanthema on palms suggested enterovirus as a possible etiologic agent. [jcm.asm.org]

Weekly Epidemiological Record = Relevé épidémiologique hebdomadaire, 46 (‎25)‎, 248 - 249. https://apps.who.int/iris/handle/10665/218374 Journal Weekly Epidemiological Record = Relevé épidémiologique hebdomadaire, 46 (‎25)‎: 248 - 249 [apps.who.int]

Epidemiology Worldwide distribution Occur in all age groups Highest incidence in infants and young children ( < 10 years ) References: [1] Epidemiological data refers to the US, unless otherwise specified. [amboss.com]

Jackson, Mississippi i Department of Epidemiology and Biostatistics, Institute for Human Genetics, University of California, San Francisco, California, USA Correspondence to Xiaofeng Zhu, Department of Epidemiology and Biostatistics, Case Western Reserve [journals.lww.com]

The differentiation between EV70 and the CA24 variant as the agent causing AHC is very important in epidemiology, especially as there is a high possibility in Japan of outbreaks caused by these two agents. [ncbi.nlm.nih.gov]

A Halapas, N Pissimissis, P Lembessis, I Rizos, AG Rigopoulos, DT Kremastinos and M Koutsilieris, Molecular diagnosis of the viral component in cardiomyopathies: pathophysiological, clinical and therapeutic implications, Expert Opinion on Therapeutic [doi.org]

Pathophysiology Coxsackieviruses are transmitted primarily via the fecal-oral route and respiratory aerosols, although transmission via fomites is possible. The viruses initially replicate in the upper respiratory tract and the distal small bowel. [emedicine.medscape.com]

Centers for Disease Control and Prevention. "Hand, Foot, and Mouth Disease." Dec. 22, 2017.. United States. Centers for Disease Control and Prevention. [medicinenet.com]

[…] contagious, and can be prevented. [microbewiki.kenyon.edu]

Is it possible to prevent coxsackievirus infections? Prevention of coxsackievirus infections is difficult but possible. [rxlist.com]