Presentation
Interestingly, erythrocytes from neither mice nor rhesus macaques present CAR. [ncbi.nlm.nih.gov]
Immune System
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Cervical Lymphadenopathy
Initial observations included a prominent cervical lymphadenopathy, exudative pharyngitis and leucocytosis with atypical lymphocytosis. At the end of the 2nd week of illness the patient developed meningoencephalomyelitis and haemolytic anaemia. [ncbi.nlm.nih.gov]
Entire Body System
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Unconsciousness
Although he was immediately resuscitated, he remained unconscious with a modified Glasgow coma score of 4 or 3. He developed neurogenic diabetes insipidus 169 hours after the convulsion and died the next day. [ncbi.nlm.nih.gov]
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Lymphadenopathy
Initial observations included a prominent cervical lymphadenopathy, exudative pharyngitis and leucocytosis with atypical lymphocytosis. At the end of the 2nd week of illness the patient developed meningoencephalomyelitis and haemolytic anaemia. [ncbi.nlm.nih.gov]
Jaw & Teeth
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Exudative Pharyngitis
Initial observations included a prominent cervical lymphadenopathy, exudative pharyngitis and leucocytosis with atypical lymphocytosis. At the end of the 2nd week of illness the patient developed meningoencephalomyelitis and haemolytic anaemia. [ncbi.nlm.nih.gov]
Eyes
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Retinal Pigmentation
A bull's eye pattern of macular retinal pigment epithelial disturbance persisted on color and near infrared reflectance images, despite good visual acuity. [ncbi.nlm.nih.gov]
Fetus
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Spontaneous Rupture of Membranes
Delivery occurred vaginally approximately 24 hours later, following spontaneous rupture of membranes. At birth, both twins showed signs of sepsis. [ncbi.nlm.nih.gov]
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Placental Disorder
Massive perivillous fibrin deposition (MPFD) is an uncommon placental disorder, associated with significant fetal morbidity, mortality, and recurrence; its etiology is unknown. [ncbi.nlm.nih.gov]
Urogenital
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Polyuria
A 65-year-old Japanese man presented to our hospital in June 2013 with a 6-day history of fever and fatigue, a 24-h history of thirst, and polyuria. His temperature was 37.8 C and he was alert. [ncbi.nlm.nih.gov]
Neurologic
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Cerebellar Ataxia
Neurological involvement associated with enterovirus 71 infection may include: Aseptic meningitis Encephalitis Encephalomyelitis Acute cerebellar ataxia Acute transverse myelitis Guillain-Barré syndrome Opsomyoclonus syndrome Benign intracranial hypertension [dermnetnz.org]
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Dizziness
A 7 year old boy had 2 episodes of mental dizziness and consciousness disturbance. Because of he presented a visus of 70 %, headaches and vomiting he was admitted to our hospital. [ncbi.nlm.nih.gov]
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Encephalopathy
The autopsy showed mild, acute pericarditis and hypoxic-ischemic encephalopathy. Placenta examination showed MPFD involving 80% of the parenchyma. Molecular viral analysis and serotyping showed Coxsackie A16 virus. [ncbi.nlm.nih.gov]
Treatment
Due to its crucial role for viral entry, CAR-downregulation may lead to novel approaches for treatment for viral myocarditis. [doi.org]
All four infants recovered, and no adverse effects of the treatment were noted. pleconaril needs to be comprehensively evaluated in this population. [ncbi.nlm.nih.gov]
Diagnostic procedures and treatment should be tailored to the specific disease manifestation. [amboss.com]
It does not provide medical advice, diagnosis or treatment. This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. [immuno-oncologynews.com]
At the end of the treatment period, mean S.D. [academic.oup.com]
Prognosis
We concluded that coxsackie virus B 4 caused acute encephalitis with ophthalmological and mental symptoms and good prognosis. Coxsackie virus B 4 should be considered in patients with encephalitis. [ncbi.nlm.nih.gov]
almost always self‑limiting Coxsackie B Myocarditis Pleurodynia Characteristics : highly contagious Clinical presentation Flu‑like symptoms Sudden thoracic and upper abdominal pain caused by irritation of the pleura and muscles Prognosis : self‑limiting [amboss.com]
The prognosis of HFMD is excellent, with the vast majority resolving spontaneously in 5-10 days. [patient.info]
Etiology
Our patient is the first reported case of FT1D associated with Coxsackie virus A2 infection and supports the etiological role of common viral infections in FT1D. [ncbi.nlm.nih.gov]
Epidemiology
The differentiation between EV70 and the CA24 variant as the agent causing AHC is very important in epidemiology, especially as there is a high possibility in Japan of outbreaks caused by these two agents. [ncbi.nlm.nih.gov]
Epidemiology Worldwide distribution Occur in all age groups Highest incidence in infants and young children ( 10 years ) References: [1] Epidemiological data refers to the US, unless otherwise specified. [amboss.com]
Epidemiology and control of hand, foot and mouth disease in Singapore, 2001-2007. Ann Acad Med Singapore. 2009 Feb. 38(2):106-12. [Medline]. Bergman I, Painter MJ, Wald ER, et al. [emedicine.medscape.com]
Pathophysiology
A Halapas, N Pissimissis, P Lembessis, I Rizos, AG Rigopoulos, DT Kremastinos and M Koutsilieris, Molecular diagnosis of the viral component in cardiomyopathies: pathophysiological, clinical and therapeutic implications, Expert Opinion on Therapeutic [doi.org]
Pathophysiology Coxsackieviruses are transmitted primarily via the fecal-oral route and respiratory aerosols, although transmission via fomites is possible. The viruses initially replicate in the upper respiratory tract and the distal small bowel. [emedicine.medscape.com]
Prevention
Centers for Disease Control and Prevention. "Hand, Foot, and Mouth Disease." Dec. 22, 2017.. United States. Centers for Disease Control and Prevention. [medicinenet.com]
Is it possible to prevent coxsackievirus infections? Prevention of coxsackievirus infections is difficult but possible. [rxlist.com]
[…] contagious, and can be prevented. [microbewiki.kenyon.edu]