In the present study, eight candidate miRNAs, the functions of which are associated with myocarditis, were selected and their expression levels were evaluated by reverse transcription-quantitative polymerase chain reaction. miR-146b and miR-214 were found [ncbi.nlm.nih.gov]

• Fatigue

  We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition. Last updated: March 8, 2020 [patientslikeme.com]

  The common symptoms of Coxsackie virus are fever, sore throat, fatigue and loss of appetite. It would be only for two or three days. Then it appears as sores and blisters on the mouth, throat and hands. [diseasespictures.com]

  Symptoms include shortness of breath, chest pain, fatigue, and leg swelling. The injury to the heart may be transient or permanent. Severe Infection of the Newborn Newborns may acquire the virus from infected adults or children. [emedicinehealth.com]

  There are also possible associations of Coxsackieviruses with post-viral fatigue syndromes, Reye's syndrome and pancreatitis. [patient.info]

• Sore Throat

  Coxsackie viruses are a common cause of sore throats, especially for children, often in spring and summer. Typical symptoms are a fever, and sore throat and tongue in some cases. [familydoctor.co.nz]

  HFMD usually causes a sore throat, fever, and the characteristic blister rash described above. It is mild and resolves on its own. [emedicinehealth.com]

• Rales

  Fine rales and wheezing were audible at both lung bases. His liver and spleen were not palpable. [journals.lww.com]

• Chest Pain

  When to Call Your Pediatrician Call your pediatrician if your child complains of neck pain, chest pain, difficulty breathing, listlessness, or lethargy. [healthychildren.org]

  Fever, headache or nonspecific abdominal pain - either as prodromal symptoms or with the onset of chest pain. May be myalgia elsewhere. Duration is normally a few days, but may be 3 weeks; it can recur/relapse. [patient.info]

  It causes a sudden onset of sharp chest pain which gets worse when taking a deep breath. Pain may also be present in the abdomen. The pain comes and goes in waves or spasms. [emedicinehealth.com]

• Left Ventricular Dysfunction

  Myocarditis Coxsackievirus B is one of the more common causes of myocarditis, with potential to progress to dilated cardiomyopathy.[6] Viral myocarditis may be asymptomatic, or may present with symptoms of heart failure and left ventricular dysfunction [patient.info]

• Lip Cyanosis

  On admission weak pulses and lip cyanosis were observed. He was intubated and transferred to our pediatric intensive care unit for further care. On admission his pulse rate was 187 beats/min and his blood pressure was 64/32 mm Hg. [journals.lww.com]

• Weak Pulse

  On admission weak pulses and lip cyanosis were observed. He was intubated and transferred to our pediatric intensive care unit for further care. On admission his pulse rate was 187 beats/min and his blood pressure was 64/32 mm Hg. [journals.lww.com]

• Headache

  Stiff neck, headache, and pain related to bright lights (photophobia) are signs of meningitis. [healthychildren.org]

  Others suddenly get a high fever, headache, and muscle aches, and some also develop a sore throat, abdominal discomfort, or nausea. A child with a coxsackievirus infection may simply feel hot but have no other symptoms. [kidshealth.org]

  Mild pyrexia, headache, sore throat, dysphagia, loss of appetite and sometimes vomiting and abdominal pain occur. [patient.info]

  Patients with aseptic meningitis complain of a headache and fever with mild neck stiffness. A rash may be present. In children, symptoms may be less specific, including change in personality or becoming lethargic. [emedicinehealth.com]

• Seizure

  Febrile seizures may occur in children. Seizures are less common in adults, although adults may complain of fatigue that lasts for weeks after the meningitis resolves. [emedicinehealth.com]

Laboratory workup revealed segmented neutrophil predominant leukocytosis, elevated levels of troponin (2.45 ng/ml), BNP (457.2 pg/ml), and d-dimer (6.72 µg/ml). [hindawi.com]

HIV infection with AIDS-defining opportunistic infections These 3 categories are further subdivided on the basis of the CD4 T-cell count, as follows: 500/µL: Categories A1, B1, C1 200-400/µL: Categories A2, B2, C2 200/µL: Categories A3, B3, C3 See Workup [emedicine.medscape.com]

However, this treatment strategy has to be evaluated in vivo to develop a new treatment strategy for patients suffering with viral myocarditis. [ncbi.nlm.nih.gov]

The viral infection is usually self-limited and no treatment is necessary. However, it is highly contagious and preventing transmission is hard. [patientslikeme.com]

Diagnostic procedures and treatment should be tailored to the specific disease manifestation. [amboss.com]

Thus, the effects of a relatively common infection during the neonatal period may be long lasting, and the prognosis for newborn infants recovering from acute infection should be reexplored. [ncbi.nlm.nih.gov]

The prognosis of HFMD is excellent, with the vast majority resolving spontaneously in 5-10 days. [patient.info]

[…] mouth disease Characteristics: highly contagious Clinical presentation General symptoms: fever, reduced general condition Skin/mucosa Maculopapular and partially vesicular rash on the hands and feet Oral ulcers Diagnosis: clinical Treatment: symptomatic Prognosis [amboss.com]

What Is the Prognosis? In most cases, children recover from these infections within 7 to 10 days without problems. [healthychildren.org]

Prognosis : There is excellent recovery from Coxsackie infection with prompt medical intervention and treatment. But things get uncontrolled if there is severe outbreak of infection wherein many children are infected and hospitalized. [diseasespictures.com]

Abstract Recently, it has been suggested that coxsackievirus plays an etiologic role in juvenile dermatomyositis (DM). [ncbi.nlm.nih.gov]

References:[2][3][4] Coxsackie virus infections Summary Epidemiology Etiology Disease manifestations [amboss.com]

The incidence of pancreatitis of unknown etiology may even be higher since the diagnosis of acute pancreatitis can be difficult and may go undetected. [pancreas.imedpub.com]

Epidemiology Worldwide distribution Occur in all age groups Highest incidence in infants and young children ( 10 years) References:[1] Epidemiological data refers to the US, unless otherwise specified. [amboss.com]

The epidemiology and pathogenicity of SAFV remain unclear. METHODS: Between July 2009 and October 2010, nasopharyngeal specimens were collected from children with acute respiratory infections. [ncbi.nlm.nih.gov]

Epidemiology[1, 2] Infection with this group of enteroviruses is very common. In temperate climates, it is most frequent in summer and autumn and, in the tropics, all year round. [patient.info]

Abstract Full Text The report is an overview of enterovirus epidemiology in Piemonte during a 5-year period from 2000 to 2004 with an investigative protocol recording epidemiologic, clinical, and laboratory data. [doaj.org]

We have recently reported the possible role of the cysteine‐rich secretory protein 3 gene (a member of the latter group of differentially expressed genes) (5) in the pathophysiology of primary SS. [onlinelibrary.wiley.com]

Pathophysiology of Coxsackie's virus Coxsackieviruses are transmitted primarily via the fecal -oral route and respiratory aerosols, although transmission via fomites is possible. [slideshare.net]

Pathophysiology Coxsackieviruses are transmitted primarily via the fecal-oral route and respiratory aerosols, although transmission via fomites is possible. The viruses initially replicate in the upper respiratory tract and the distal small bowel. [emedicine.medscape.com]

Centers for Disease Control and Prevention. "Hand, Foot, and Mouth Disease." Dec. 22, 2017. . United States. Centers for Disease Control and Prevention. [medicinenet.com]

Two weeks before the outbreak of the lesions, the patient had suffered from a viral pharyngitis, subsequently diagnosed as herpangina, and had been taking an oral cephalosporin (cefixime) for 1 week to prevent possible bacterial complications. [ncbi.nlm.nih.gov]

Tips For Prevention : Children should be instructed to wash their hands properly before eating and after using the toilet. Parents should not send the infected child to school or day care center to prevent spreading of infection to many others. [diseasespictures.com]

There is no vaccine to prevent coxsackievirus infection. Hand washing is the best protection. [kidshealth.org]