Presentation
Case Presentation: A 19-year-old female with mild persistent asthma, borderline personality disorder, and substance abuse presented with three days of a non-productive cough and dyspnea. [shmabstracts.com]
[…] disorder, and substance abuse presented with three days of a non-productive cough and dyspnea. [shmabstracts.org]
Keywords Abstract We present a case-report of a 15-year-old girl who developed severe respiratory failure following illicit drug use in the context of an unusual social background. [morressier.com]
She had a past medical history of cocaine abuse and agreed that she used cocaine 2 days prior to presentation. On admission, her vitals included Blood Pressure of 160/70, Heart Rate—110, Respiratory Rate—36 with oxygen saturation of 78%. [semanticscholar.org]
Abstract In this report, we review the hospital course of four patients who presented with an acute pulmonary syndrome after inhaling freebase cocaine and compare them with previously described case reports. [wwww.unboundmedicine.com]
Entire Body System
- Fever
Two patients had prolonged inflammatory pulmonary injury associated with fever, hypoxemia, hemoptysis, respiratory failure, and diffuse alveolar infiltrates. [wwww.unboundmedicine.com]
The illness typically causes fever, coughing, phlegm, intense pain, and bleeding from the lungs. Crack lung sometimes shows up as lung abnormalities on X-rays, though this is not always the case. [radiopaedia.org]
From WikEM Background Due to hemorrhagic alveolitis from inhalational cocaine use [1] Clinical Features Most common symptoms are cough and shortness of breath Others include: acute lung injury hypoxia chest pain hemoptysis fever focal infiltrates bronchospasm [medbox.iiab.me]
- Weakness
If this muscle is weak it can cause the knee cap to track incorrectly and that is when you hear a cracking sound as you squat down or lung. [nicksivrichptanswersnow.wordpress.com]
Damaging the lung’s cilia, the respiratory system’s first line of defence, can have severe consequences for people with weak immune systems. Taking crack or cocaine can cause many lung problems. [lovedonesunite.com]
Anyway these horrid diseases lead to a frozen diaphragm and since my heart valves are made up of weak collagen it taxes my heart immensely; 20 minutes on this thing and my dislocated shoulders are starting to drop after 9 months of agony. [amazon.com]
Damaging the lung's cilia,the respiratory system's first line of defense, can have severe consequences for people with weak immune systems, the studies note. [archives.drugabuse.gov]
- Intravenous Drugs
Bullous pulmonary damage in users of intravenous drugs. Chest 1986 ; 89: 266–269. Crossref, Medline, Google Scholar 65 O’Donnell AE, Pappas LS. Pulmonary complications of intravenous drug abuse: experience at an inner-city hospital. [pubs.rsna.org]
Persons with a history of intravenous drug abuse also are more likely to have tuberculosis of the lungs. The drug heroin can produce a nephropathy in the kidney that resembles focal segmental glomerulosclerosis. [lovedonesunite.com]
[…] cocaine users than in any other intravenous drug users.[6,10] It is caused when bacteria enters the bloodstream via unsterile needles and attaches itself to the heart valve. [methoide.fcm.arizona.edu]
These occur as a result of impaired judgment while high on crack that can cause an individual to engage in promiscuous sexual relations or intravenous drug use. [mentalhelp.net]
In general, some drug users grind medicine tablets down, dissolve them with water and inject such a solution intravenously (40-42). [rb.org.br]
- Congestive Heart Failure
Dyspnoea, fatigue, orthopnoea, paroxysmal nocturnal dyspnoea, frothy pink sputum - suggestive of congestive heart failure. Dyspnoea and pleuritic chest pain - consider a PE. Signs Record vital signs, including oxygen saturation levels. [patient.info]
This can lead to an increased risk of heart arrhythmias, heart attack and congestive heart failure. Coronary atherosclerosis may also develop from long-term crack use. [luxury.rehabs.com]
A positive gallium scan result is seen in almost all patients with amiodarone pneumonitis and can help differentiate it from pulmonary embolism and congestive heart failure. [emedicine.medscape.com]
Other cardiovascular complications resulting from cocaine abuse are ventricular arrhythmias, congestive heart failure, aortic dissection, intramural hematoma of the aorta, dilated cardiomyopathy, and sudden death (, 5,, 19 –, 21 ). [pubs.rsna.org]
Respiratoric
- Cough
[…] alot of that coughing comes from the butane, the coating on whatever you used for screens plus whatever nasty cut was put in the stuff. after i stopped smoking it, i eventually finished coughing hopefully all that stuff out. my voice got back or closer [medhelp.org]
This leads to shortness of breath, coughing and lack of endurance during exercise. Emphysema is one type of chronic obstructive pulmonary disease (COPD), and is often seen in combination with chronic bronchitis. [abcnews.go.com]
(with pictures) wisegeek.com Get Rid Of Cough And Extra Mucus From The Lungs Carrots are extremely beneficial for our health, rich in Vitamins A and B, important in eye function. [diaconiacrd.org]
They usually have trouble breathing, have coughing fits and will cough up blackish residue. A few of the addicts have had to be hospitalized due to difficulty breathing and were probably experiencing crack lung. [wisegeek.com]
In some cases, hemorrhaging of capillaries in the lungs leads to coughing that produces black or bloody sputum. [drugaddictiontreatment.com]
- Dyspnea
In contrast, two patients presented acutely with diffuse pulmonary alveolar infiltrates associated with dyspnea and hypoxemia, but without fever, and within 36 h of discontinuing cocaine their pulmonary infiltrates and symptoms had spontaneously resolved [wwww.unboundmedicine.com]
Chest pain and dyspnea related to crack cocaine smoking: value of chest radiography. Radiology 1989; 172(2): 459-462. [ Links ] 9. Gotway MB, Marder SR, Hanks DK, Leung JW, Dawn SK, Gean AD, et al. [scielo.br]
Patients present with sympathetic hyperactivity such as tachycardia, hypertension, dilated pupils, and chest pain, productive cough, dyspnea, and hypoxemia along with fever, hemoptysis, and respiratory failure 1,3. [radiopaedia.org]
Patients who have developed amiodarone-induced lung toxicity usually present with nonspecific symptoms such as cough, dyspnea, fever, and weight loss. [emedicine.medscape.com]
- Painful Cough
Brief Report: PDF Only Abstract ABSTRACT: We describe the bronchoalveolar lavage appearance in a patient presenting with chest pain, cough, shortness of breath, and diffuse interstitial infiltrates after the inhalation of crack cocaine. [journals.lww.com]
Symptoms may include: difficulty breathing, such as: wheezing shortness of breath even breathing failure severe chest pain coughing, including coughing up blood from the lungs low blood oxygen collapsed or inflamed lungs that fill up with fluid People [canada.ca]
Also, with crack lung, the difference in that and a respiratory infection like you had that you didnt mention above is with crack lung one almost always has severe lung pain and coughing up blood (which you didnt mention happened to you). [bluelight.org]
Chest pain is secondary, affecting 38% (pleurisy in 64% of patients with pain). [emedicine.medscape.com]
- Respiratory Distress
Adult Respiratory Distress Syndrome Definition Adult respiratory distress syndrome (ARDS), also called acute respiratory distress syndrome, is a type of lung (pulmonary) failure that may result from any disease that causes large amounts of fluid to collect [medical-dictionary.thefreedictionary.com]
Distress Syndrome Network: Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. [books.google.com]
Complications acute respiratory distress syndrome (ARDS) end-stage respiratory failure radiological manifestations of recreational drug use References Promoted articles (advertising) [radiopaedia.org]
Chronic cough, higher risk of infections like pneumonia and tuberculosis, acute respiratory distress, asthma, and pulmonary edema are all associated with freebasing cocaine. [americanaddictioncenters.org]
Conclusions Patients who present respiratory distress, unrespon-sive to antibiotics and anti-inflammatory treatment, in a high suggestive context of a lung interstitial syndrome, should be explored for PLC by extended investigations (especially endoscopies [pneumologia.eu]
- Rales
Rales can be further described as moist, dry, fine, and coarse. Rhonchi: Sounds that resemble snoring. They occur when air is blocked or air flow becomes rough through the medium-sized airways, most often with secretions. [en.wikipedia.org]
Some of the symptoms include Dyspnea at rest Exertional cyanosis Lung signs/abnormality Painful cough Pulmonary Crackles Rales Rales,dry Rhonchi/coarse rales Shortness of breath/SOB Sudden onset dyspnea Wheezing Voice Alteration Fever Fever Febrile Possible [bluelight.org]
Lung signs that may be found with haemoptysis include: Fine inspiratory rales (associated with alveolar blood). Inspiratory and expiratory rhonchi (associated with airway secretions and blood). [patient.info]
Exam findings may include rales on examination and respiratory failure. [pulmonologyadvisor.com]
Gastrointestinal
- Nausea
Other short-term effects include: higher heart rate, breathing rate, blood pressure, and body temperature decreased appetite and less need for sleep feelings of restlessness, irritability, or paranoia nausea and possibly vomiting respiratory problems [kidshealth.org]
Less blood flow to the stomach and bowels causes symptoms of abdominal pain, decreased appetite, nausea, vomiting and constipation. It also increases the risk for a condition called necrotic bowel. [livestrong.com]
[…] decrease in need for food and sleep experiencing a heightened sense of sight, sound and touch dry mouth quicker startle reflexes and muscle twitches widened (dilated) pupils of the eyes restlessness and irritability More severe effects can include: nausea [canada.ca]
Loss of appetite Increased heart rate, blood pressure, body temperature Contracted blood vessels Increased rate of breathing Dilated pupils Disturbed sleep patterns Nausea Hyperstimulation Bizarre, erratic, sometimes violent behavior Hallucinations, hyperexcitability [drugfreeworld.org]
Haemoptysis Haematemesis No nausea or vomiting Nausea and vomiting Concurrent lung disease Concurrent gastric or hepatic disease Sputum is frothy Vomitus is rarely frothy Sputum has a liquid or clotted appearance Typical coffee ground appearance Haemoptysis [patient.info]
Cardiovascular
- Thrombosis
Underlying mechanism is believed to be stasis in pulmonary circulation leading to in situ thrombosis. Figure 1. A. Cocaine-induced diffuse alveolar hemorrhage. B. Cocaine-induced in situ lung thrombosis (shown by arrow). Figure 1. A. [academic.oup.com]
CT scan of the chest was performed, which revealed diffuse ground glass opacity consistent with cocaine-induced lung injury—crack lung (Figure 1A) as well as cocaine-induced in situ thrombosis (Figure 1B). [zdoc.site]
Gene-gene and gene-environment interactions determine risk of thrombosis in families with inherited antithrombin deficiency. Blood 1999; 94:2590 –2594 De Stefano V, Chiusolo P, Paciaroni K. [kundoc.com]
[…] ischemia Increased myocardial O2 demand Due to sympathomimetic actions and increased inotropy, HR and BP Coronary artery vasospasm Primary alpha-adrenergic receptors Some cholinergic role Impairs endothelium dependent vasorelaxation Coronary artery thrombosis [radiology.vcu.edu]
Psychiatrical
- Anger
Crack is also known to cause extreme paranoia, anger, hostility, and anxiety even when a user is not high, or the drug has completely worn off. Crack use can produce many short-term physiological effects including: Restlessness. Irritability. [orlandorecovery.com]
Feelings of anger, paranoia and anxiety may also occur. The longer the person uses crack, the worse they will feel afterwards. Feelings of depression will get worse, even to the point of suicide. They may even suffer from hallucinations. [neaddictions.com]
[…] breathing Hallucinations Once the high is over, the other face of the drug appears, and the user begins to experience the negative effects:³ Nagging, obsessive cravings for the drug (even if the person doesn’t want to use it again) Anxiety, paranoia Anger [yellowstonerecovery.com]
[…] they stay irritated...Im planning on quiting next year when ill be more settle in my recovery and outta my parents house...cause i know if i do it now it be setting myself up for failure cause living with my drunk dad doesnt help with my anxiety and anger [soberrecovery.com]
The person who abuses cocaine may exhibit excessive anger, particularly when confronted about their drug use or associated behaviors. Their personality may seem to change as well. [emedicinehealth.com]
- Addictive Behavior
These behaviors are all signs of cocaine addiction or at least cocaine abuse and dependency that is on its way to becoming a full-blown addiction. [delphihealthgroup.com]
Inpatient treatment can provide a stable and supportive environment where individuals are more likely to break their addictive behaviors towards crack cocaine. [addictioncampuses.com]
It is also referred to as chemical dependency and addictive behavior. Drug-use disorders spare no one and are spread throughout society. They are not limited by age, profession, race, religion, or physical attributes. [emedicinehealth.com]
Neurologic
- Irritability
Infectious diseases and abscesses if injected Malnutrition, weight loss Severe tooth decay Auditory and tactile hallucinations Sexual problems, reproductive damage and infertility (for both men and women) Disorientation, apathy, confused exhaustion Irritability [drugfreeworld.org]
Smoking large doses of crack or doing crack in binges can make people edgy and irritable. They may have panic attacks and full-blown psychosis where they hear voices and have trouble staying in touch with reality. [kidshealth.org]
Psychologically, the drug reduces concentration, ambition, drive, and increases confusion and irritability, wreaking havoc on users' professional and personal lives. [drugrehab.co.uk]
Irritability. Anxiety. Panic. Nausea. Depression. Dilated pupils. Increased body temperature. Increased heart rate. Muscle spasms or twitching. Convulsions. Hallucinations. Vertigo. Panic and psychosis. [orlandorecovery.com]
- Agitated Delirium
Withdrawal from alcohol or sedative-hypnotics may cause the triad of hyperthermia, agitated delirium, and seizures. Phases of acute cocaine toxicity Three phases are reported. [emedicine.medscape.com]
Workup
Frankel Medicine 2011 Clinical features, general diagnostic workup, and management of the eosinophilic lung diseases, a heterogeneous group of disorders characterized by an increased numbers of eos in 1 or more compartments of the lung, radiographic abnormalities [semanticscholar.org]
In this case, a crack cocaine user presented with significant hypoxia, nonspecific chest X-ray abnormalities, with workup revealing AEP that responded well to steroids and avoidance of the offending agent. [shmabstracts.com]
The greatest progress in the management of CTEPH is the clinical awareness of the disease and the diagnostic workup of surgical thrombus accessibility.1,5–7 The present case is unique in that it demonstrates a rare combined thrombophilic defect underlying [kundoc.com]
X-Ray
- Pulmonary Infiltrate
Inspection of the hands for burns consistent with handling cocaine pipes should prompt a consideration of crack lung in patients with pulmonary infiltrates. [ncbi.nlm.nih.gov]
In contrast, two patients presented acutely with diffuse pulmonary alveolar infiltrates associated with dyspnea and hypoxemia, but without fever, and within 36 h of discontinuing cocaine their pulmonary infiltrates and symptoms had spontaneously resolved [wwww.unboundmedicine.com]
[…] lung disease (4) heavy use of crack cocaine (5) smoking other drugs of abuse (6) cigarette smoking Clinical features of "crack lung" syndrome: (1) cough (2) absent or low grade fever (3) dyspnea (4) hypoxemia (5) pulmonary infiltrate on chest X-ray [meducator3.net]
[…] toxic effect on capillary endothelium Intense vasoconstrictor effect leads to anoxic cell damage Bronchiolitis obliterans with organizing pneumonia (BOOP) Pulmonary infiltrates with eosinophilia Adulterants have been implicated in producing hypersensitivity [learningradiology.com]
- X-Ray Abnormal
In this case, a crack cocaine user presented with significant hypoxia, nonspecific chest X-ray abnormalities, with workup revealing AEP that responded well to steroids and avoidance of the offending agent. [shmabstracts.com]
- Chest X-Ray Abnormal
A chest X-ray showed a streaky opacity in the left lingula and possible trace bilateral pleural effusions. [shmabstracts.com]
- Bilateral Pulmonary Infiltrates
Several pulmonary complications are associated with the inhalation of crack cocaine (e.g., intensive cough, hemoptysis, shortness of breath, chest pain, acute bilateral pulmonary infiltrates, thermal airway injury, pneumothorax and noncardiogenic pulmonary [wwwnc.cdc.gov]
Microbiology
- Staphylococcus Aureus
NIDA-funded studies show that alveolar macrophages from crack cocaine smokers are less active than are alveolar macrophages from nonsmokers in destroying Staphylococcus aureus, a common cause of bacterial lung infection. [archives.drugabuse.gov]
Further complicating matters is the higher association of illicit drug use with antibiotic resistant organisms including methicillin-resistant Staphylococcus aureus. [posterng.netkey.at]
Pulmonary Function Test
- Decreased Lung Compliance
hypoxemia, and decreased lung compliance. [medical-dictionary.thefreedictionary.com]
Treatment
Let our treatment experts call you today. Talk to a treatment care expert today. Our treatment experts are equipped to answer your questions about our facility, insurance and how to live a life free from addiction. [pathwaytohope.net]
Quora Crack Lung Drug Addiction Treatment Crack Lung Drug Addiction Treatment How To Get Rid Of Crack Lung 3/06/2018 · Also, with crack lung, the difference in that and a respiratory infection like you had that you didnt mention above is with crack lung [diaconiacrd.org]
Anxiety Treatment Our inpatient anxiety treatment centers help people overcome the effects of anxiety disorders. Trauma & PTSD Treatment Residential PTSD programs offer a private, secluded place where the emphasis is on treatment. [promises.com]
Can be associated with diffuse alveolar hemorrhage or eosinophilia on bronchoscopy Treatment is supportive with O2, bronchodilator therapy, and ventilation when indicated. [ucsfmed.wordpress.com]
Outpatient treatment may also be used as a direct follow-up to residential treatment. [yellowstonerecovery.com]
Prognosis
[…] and include 2-4: pulmonary alveolar and interstitial edema, predominantly perihilar pulmonary hemorrhage barotrauma: pneumothorax; pneumomediastinum; pneumopericardium localized atelectasis or consolidation empyema rich in eosinophils Treatment and prognosis [radiopaedia.org]
Prognosis Haemoptysis may be a mild, self-limiting symptom or may herald serious underlying disease. Massive haemoptysis can directly cause death and has a bad prognosis, worse in some groups such as those with an underlying cancer. [patient.info]
Massive haemoptysis can directly cause death and has a bad prognosis, worse in some groups such as those with an underlying cancer. To learn more about how Sober Nation operates, please. [ideafit.com]
The prognosis of PLC is particularly grim, with approximately 50% to 85% of patients dying within 3-6 months of diagnosis(1,2,8,9). [pneumologia.eu]
The prognosis is good. Most patients improve after discontinuation of the gold therapy. Penicillamine Penicillamine is an anti-inflammatory agent mostly used in the treatment of rheumatoid arthritis. [emedicine.medscape.com]
Etiology
Drawing on the latest work in medicine, psychiatry, neuroscience, pharmacology, epidemiology, social work, and sociology, the volume is a highly accessible reference on the history and use of cocaine, its physical and psychological effects, and the etiology [books.google.com]
Treatment is directed at the underlying etiology and typically includes corticosteroids, total plasma exchange, and immunosuppressant therapy. [pulmonologyadvisor.com]
We speculate about the etiology and mechanism for recurrent hemorrhage. [kundoc.com]
Gastric biopsy confirmed the etiology of PLC: undifferentiated adenocarcinoma of the stomach. [pneumologia.eu]
Epidemiology
[…] and epidemiology of cocaine addiction. [books.google.com]
Bothamley) ; University College London Centre for Infectious Disease Epidemiology, London (A. [wwwnc.cdc.gov]
Epidemiology Haemoptysis is common. In most cases, it is mild, self-limiting and related to transitory infection but it should be considered a serious sign due to the risk of underlying pathology. [patient.info]
Pathophysiology
NIDA conference report on cardiopulmonary complications of "crack" cocaine use: Clinical manifestations and pathophysiology. Chest 110:1072-1076, 1996. [archives.drugabuse.gov]
Cocaine: pathophysiology and clinical toxicology. Heart Lung, 26 (6), 466. Brust, J. C. (1998). Acute neurologic complications of drug and alcohol abuse. Neurol Clin., 16 (2), 503. Neiman, J., Haapaniemi, H. M., Hillbom, M. (2000). [luxury.rehabs.com]
Pharmacology: Local anesthetic Stabilizes cell membranes and blocks neuronal sodium channels Also a sympathomimetic and CNS stimulant Interferes with reuptake of catecholamines and serotonin Methods of abuse Snorted Smoked Pathophysiology Methods of pulmonary [radiology.vcu.edu]
In this article, we describe cocaine and its abuse, after which we discuss and illustrate the pathophysiologic and imaging features of the aforementioned complications. [pubs.rsna.org]
Prevention
Each ligament prevents the knee from going in a certain direction. ACL prevents the shin bone from going forwards, the PCL prevents the shin from going backwards and the MCL/LCL prevents the knee from going side to side. [nicksivrichptanswersnow.wordpress.com]
Prevention of bacterial endocarditis. الصفحة 303 - American Thoracic Society. Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthma. [books.google.com]
The two best ways to beat lung cancer is to: Prevent lung cancer by minimizing or eliminating risk factors, and Detect lung cancer at its earliest and most treatable stage. [roswellpark.org]
Primary, secondary and terciary prevention of addiction with evidence based pharmacological treatment of alcohol, cocaine and other stimulants and opiates addiction is discussed. [books.google.ro]
Crack Cocaine Overdose Prevention The best prevention plan against crack cocaine overdose is abstinence. The addictive nature of crack cocaine makes any use of the drug dangerous. [addictioncampuses.com]