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Cranial Neuropathy

Cranial Nerve Disorder


Presentation

  • RESULTS: Cranial neuropathy was the presenting symptom of recurrent disease in all six patients. Four presented with multiple cranial neuropathies. All exhibited neuropathy of the trigeminal nerve (cranial nerve V).[ncbi.nlm.nih.gov]
Whipple Disease
  • View/Print Table TABLE 2 Distal Symmetric Sensorimotor Polyneuropathies Endocrine diseases Diabetes mellitus Hypothyroidism Acromegaly Nutritional diseases Alcoholism Vitamin B 12 deficiency Folate deficiency Whipple's disease Postgastrectomy syndrome[aafp.org]
Splenectomy
  • The abnormal platelet count was unresponsive to multiple-drug therapy and splenectomy, but normalized 13 months after presentation.[ncbi.nlm.nih.gov]
Formication
  • All patients were multiply symptomatic, presenting with a mean of three neurologic symptoms, including facial numbness (5), facial paralysis or weakness (3), facial pain (3), diplopia (3), paresthesia (3), hearing loss (1), or formication (2).[ncbi.nlm.nih.gov]
Diplopia
  • The syndrome consists of headache, facial pain and diplopia preceding the onset of cranial nerve palsy. The cranial nerves most frequently involved were the third, fifth and seventh. All patients were treated with corticosteroid therapy.[ncbi.nlm.nih.gov]
  • 3, 4, 5) causing diplopia (disorder) Multiple cranial neuropathy Neuropathy (nerve damage), multiple cranial ICD-9-CM Volume 2 Index entries containing back-references to 352.9 :[icd9data.com]
  • -Variable diplopia and ptosis due to fatigue. -Diagnosis: Edrophonium test -Treatment: neostigmine ( acetylcholine esterase inhibitor), thymectomy. Ocular myositis -Inflammation of the extraocular muscles -Pain, diplopia and restriction of movement.[flashcardbook.com]
  • Sixth nerve palsy is a condition which is associated with damage to the sixth cranial nerve resulting in abnormal movement of the eye and diplopia.[simple-remedies.com]
Strabismus
  • […] plexus disorders G52 ICD-10-CM Diagnosis Code G52 Disorders of other cranial nerves 2016 2017 2018 2019 Non-Billable/Non-Specific Code Type 2 Excludes disorders of acoustic [8th] nerve ( H93.3 ) disorders of optic [2nd] nerve ( H46, H47.0 ) paralytic strabismus[icd10data.com]
  • Strabismus in Art Images of strabismus in works of art are not rare. One may come across both forms of strabismus: eso- and exotropia.[karger.com]
  • The clinician must exclude minor degrees of incomitant strabismus (by careful alternate cover testing or by Maddox rod testing in all positions of gaze) to exclude subtle findings of a third nerve palsy before concluding that the problem is limited to[aao.org]
Cranial Nerve Involvement
  • Thus, for example, cytomegalovirus infection has been associated with anti-GM2 antibodies and Guillain-Barré syndrome variants with severe sensory loss and cranial nerve involvement.[ncbi.nlm.nih.gov]
  • In our study cranial nerve involvement was seen in 38 (62.3%) patients.[ruralneuropractice.com]

Workup

  • Beal that neoplastic processes are an important cause of multiple cranial neuropathy (Feb. 15 issue). 1 CT, magnetic resonance imaging, radionuclide scanning, and blood and spinal fluid studies are all important diagnostic tests in the workup of multiple[nejm.org]
Liver Biopsy
  • The liver biopsy was performed for hepatic lesion. MTX was discontinued, but no improvement of PHL and elevated liver enzyme was observed during the 3 weeks.[ncbi.nlm.nih.gov]

Treatment

  • Lower morbidity and higher occlusion rates obtained with the PED may suggest it as treatment of choice for some of these lesions. Time to treatment is an important consideration regardless of treatment modality.[ncbi.nlm.nih.gov]

Prognosis

  • Although prognosis for recovery was better in the nonmetastatic group, there was no significant difference in survival between the metastatic and the nonmetastatic groups.[ncbi.nlm.nih.gov]
  • The nerve palsy resolves once the underlying cause is treated There is no effective prevention of Cranial Mononeuropathy VI, since it is caused by variety of factors that may be unrelated to each other The prognosis of Cranial Mononeuropathy VI depends[dovemed.com]
  • Prognosis is good. Many people get better over 3 to 6 months. However, some people have permanent eye muscle weakness.[medlineplus.gov]
  • The prognosis is good, with significant recovery over 2 months (717), though complete resolution may take up to 18 months.[neuroophthalmology.ca]

Etiology

  • The etiology of CN was metastatic in 25 (83%) and nonmetastatic in 5 (17%). Only 6 patients improved: 3 metastatic and 3 nonmetastatic.[ncbi.nlm.nih.gov]

Epidemiology

  • Clinical and epidemiological features of Guillain-Barré syndrome. J Infect Dis 1997;176(Suppl 2):S92-8. 3. Hung PL, Chang WN, Huang LT, Huang SC, Chang YC, Chang CJ, et al.[ruralneuropractice.com]
  • Idiopathic chronic inflammatory demyelinating polyneuropathy: an epidemiological study in Italy. J Neurol Neurosurg Psychiatry 2007; 78(12):1349–53. Epub 2007 May 10. CrossRef PubMed Google Scholar 8. Busby M, Donaghy M.[link.springer.com]
  • Small infections can progress to ulceration and this may require amputation. [25] Epidemiology [ edit ] Globally diabetic neuropathy affects approximately 132 million people as of 2010 (1.9% of the population). [26] Diabetes is the leading known cause[en.wikipedia.org]
Sex distribution
Age distribution

Pathophysiology

  • The pain may manifest in any of many distinct forms that are believed to reflect differences in neural pathophysiologies, even if the details are not well known.[ichd-3.org]
  • Pinealoma Para Myokymia of the superior oblique muscle (typically with brief episodic ocular movements that cause subjective visual shimmering, ocular trembling, and/or tilted vision) Entrapment of the trochlear nerve by a vascular loop (similar to the pathophysiology[msdmanuals.com]
  • Pathophysiology Although peripheral neuropathy has multiple etiologies, the nerve has a limited number of ways to respond to injury. 4, 5 The damage can occur at the level of the axon (i.e., axonopathy).[aafp.org]
  • The pathophysiology is unclear but may be either vasculitis or inflammatory neuritis. Cases have been treated with intravenous steroids or acyclovir, but their efficacy is unknown.[neuroophthalmology.ca]

Prevention

  • Prevention of late-RAD is paramount because the functional impairment can be profound and refractory to standard therapies.[ncbi.nlm.nih.gov]
  • The nerve palsy resolves once the underlying cause is treated There is no effective prevention of Cranial Mononeuropathy VI, since it is caused by variety of factors that may be unrelated to each other The prognosis of Cranial Mononeuropathy VI depends[dovemed.com]
  • The treatment regimen usually focuses on alleviating the symptoms and preventing further damage.[simple-remedies.com]
  • Any reference to a specific product is for your information only and is not intended to diagnose, treat, cure, or prevent any disease[mcvitamins.com]
  • Can peripheral neuropathy be prevented? Lifestyle choices can play a role in preventing peripheral neuropathy.[vidanthealth.com]

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