At present, the genetic basis determining the different phenotypes observed in our twins is unknown. [ncbi.nlm.nih.gov]

Clinical description Craniorachischisis totalis, the most complete form of craniorachischisis, presents anencephaly and total spina bifida together and is lethal. [orpha.net]

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  general pathologists, neurologists, and geneticists in deciphering the pathology and pathogenesis of these complex disorders affecting the nervous system of the embryo, fetus, and child. [books.google.es]

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Practical, clinically relevant material facilitates the diagnosis and treatment of musculoskeletal, pain, and chronic disabling conditions. [books.google.com]

The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment. [orpha.net]

However, a variety of treatments can sometimes prevent further damage and help with complications. NIH: National Institute of Child Health and Human Development Anencephaly (Medical Encyclopedia) [ Read More ] [icdlist.com]

Remarkably intracardiac defects do not seem to affect prognosis much. [alliedacademies.org]

(Outcomes/Resolutions) The prognosis of Craniorachischisis is extremely poor, since the condition almost always results in fatalities. [dovemed.com]

Treatment and prognosis Prognosis is poor and death often occurs in utero however live births are possible 1,2. neural tube defects anencephaly References Promoted articles (advertising) [radiopaedia.org]

The prognosis of Cantrell pentalogy is related to the severity of defects identified. [ijcasereportsandimages.com]

We suggest that other PCP genes should be considered as candidates for a role in the etiology of human NTDs. Further investigations are therefore necessary. [ncbi.nlm.nih.gov]

Etiology As with other neural tube defects, craniorachischisis is thought to be of multifactorial origin. Antenatal diagnosis Antenatal diagnosis is possible by ultrasonographic monitoring. [orpha.net]

Etiology, pathogenesis and prevention of neural tube defects. Congenit. Anom. 2006, 46, 55–67. 11. Tania M, Jean-Paul Borg. Neural Tube Defects: From a Proteomic Standpoint. Metabolites 2015, 5,164-183. 12. Copp, A.J.; Greene, N.D. [jmscr.igmpublication.org]

(Etiology) The cause of Craniorachischisis is thought to be multifactorial, which means that a combination of genetic and non-genetic factors play a role. [dovemed.com]

Summary Epidemiology The prevalence is not known. Clinical description Craniorachischisis totalis, the most complete form of craniorachischisis, presents anencephaly and total spina bifida together and is lethal. [orpha.net]

Detrait ER, George TM, Etchevers HC, Gilbert JR, Vekemans M, Speer MC: Human Neural Tube Defects: Developmental biology, epidemiology and genetics. Neurotoxicology& Teratology, 2005; 27(3): 515–524. 15. [jmscr.igmpublication.org]

Clinical and epidemiologic notes Craniorachischisis is a lethal condition and is often an isolated, non-syndromic anomaly. Eyes are normally formed; bulging is a result of absence of the frontal portion of the cranial vault. [cdc.gov]

Preventing neural tube defects Research date: 1 June 2018 - 30 September 2020 Grant amount: 189,516.00 Neural tube defects (NTDs) are severe developmental abnormalities that affect a baby’s brain, spine, or spinal column. [action.org.uk]

However, a variety of treatments can sometimes prevent further damage and help with complications. NIH: National Institute of Child Health and Human Development Anencephaly (Medical Encyclopedia) [ Read More ] [icdlist.com]

Therefore emphasis was based on prenatal diagnosis and prevention. Methods and Results: The present study includes 1000 live births with 100 stillborn foetuses and abortuses to elucidate Craniorachischisis. [jmscr.igmpublication.org]